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Erschienen in: Uro-News 12/2014

09.12.2014 | Zertifizierte Fortbildung

PET/CT in der Tumornachsorge

Vielversprechendes Diagnostikum für urologische Tumoren

verfasst von: Dr. med. Julius van Essen, David Pfister, Axel Heidenreich

Erschienen in: Uro-News | Ausgabe 12/2014

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Zusammenfassung

Die Kombination der Positronen-Emmissions-Tomografie (PET) mit der Computertomografie (CT) zählt zu den modernsten bildgebenden Verfahren zur frühzeitigen Entdeckung und Kontrolle des Behandlungserfolgs bei einer Vielzahl von Tumoren. Auch in der urologischen Onkologie hat die PET/CT in den vergangenen Jahren an Bedeutung gewonnen und das Verfahren zu einem vielversprechenden Diagnostikum für urologische Tumoren gemacht. Die Indikation zur Anwendung der PET/CT unterscheidet sich jedoch im klinischen Alltag bei den verschiedenen Tumorentitäten im Urogenitaltrakt.
Literatur
1.
Zurück zum Zitat Powles T et al. Molecular positron emission tomography and PET/CT imaging in urological malignancies. Eur Urol. 2007;51(6):1511–20.PubMedCrossRef Powles T et al. Molecular positron emission tomography and PET/CT imaging in urological malignancies. Eur Urol. 2007;51(6):1511–20.PubMedCrossRef
2.
Zurück zum Zitat Phelps ME. Inaugural article: positron emission tomography provides molecular imaging of biological processes. Proc Natl Acad Sci USA. 2000;97(16):9226–33.PubMedCentralPubMedCrossRef Phelps ME. Inaugural article: positron emission tomography provides molecular imaging of biological processes. Proc Natl Acad Sci USA. 2000;97(16):9226–33.PubMedCentralPubMedCrossRef
3.
4.
Zurück zum Zitat Kosuda S et al. Preliminary assessment of fluorine-18 fluorodeoxyglucose positron emission tomography in patients with bladder cancer. Eur J Nucl Med. 1997;24(6):615–20.PubMed Kosuda S et al. Preliminary assessment of fluorine-18 fluorodeoxyglucose positron emission tomography in patients with bladder cancer. Eur J Nucl Med. 1997;24(6):615–20.PubMed
5.
Zurück zum Zitat Drieskens O et al. FDG-PET for preoperative staging of bladder cancer. Eur J Nucl Med Mol Imaging. 2005;32(12):1412–7.PubMedCrossRef Drieskens O et al. FDG-PET for preoperative staging of bladder cancer. Eur J Nucl Med Mol Imaging. 2005;32(12):1412–7.PubMedCrossRef
6.
Zurück zum Zitat Bachor R et al. Lymph node staging of bladder neck carcinoma with positron emission tomography. Urologe A. 1999;38(1):46–50.PubMedCrossRef Bachor R et al. Lymph node staging of bladder neck carcinoma with positron emission tomography. Urologe A. 1999;38(1):46–50.PubMedCrossRef
7.
Zurück zum Zitat Heicapell R et al. Staging of pelvic lymph nodes in neoplasms of the bladder and prostate by positron emission tomography with 2-[(18)F]-2-deoxy-D-glucose. Eur Urol. 1999;36(6):582–7.CrossRef Heicapell R et al. Staging of pelvic lymph nodes in neoplasms of the bladder and prostate by positron emission tomography with 2-[(18)F]-2-deoxy-D-glucose. Eur Urol. 1999;36(6):582–7.CrossRef
8.
Zurück zum Zitat Swinnen G et al. FDG-PET/CT for the preoperative lymph node staging of invasive bladder cancer. Eur Urol. 2009;57(4):641–7.PubMedCrossRef Swinnen G et al. FDG-PET/CT for the preoperative lymph node staging of invasive bladder cancer. Eur Urol. 2009;57(4):641–7.PubMedCrossRef
9.
Zurück zum Zitat Kibel AS et al. Prospective study of [18F]fluorodeoxyglucose positron emission tomography/computed tomography for staging of muscle invasive bladder carcinoma. J Clin Oncol. 2009;27(26):4314–20.PubMedCentralPubMedCrossRef Kibel AS et al. Prospective study of [18F]fluorodeoxyglucose positron emission tomography/computed tomography for staging of muscle invasive bladder carcinoma. J Clin Oncol. 2009;27(26):4314–20.PubMedCentralPubMedCrossRef
10.
Zurück zum Zitat Roehl KA et al. Cancer progression and survival rates following anatomical radical retropubic prostatectomy in 3,478 consecutive patients: long-term results. J Urol. 2004;172(3):910–4.PubMedCrossRef Roehl KA et al. Cancer progression and survival rates following anatomical radical retropubic prostatectomy in 3,478 consecutive patients: long-term results. J Urol. 2004;172(3):910–4.PubMedCrossRef
11.
Zurück zum Zitat Mitchell CR et al. 20-year survival after radical prostatectomy as initial treatment for cT3 prostate cancer. BJU Int. 2012;110(11):1709–13.PubMedCrossRef Mitchell CR et al. 20-year survival after radical prostatectomy as initial treatment for cT3 prostate cancer. BJU Int. 2012;110(11):1709–13.PubMedCrossRef
12.
Zurück zum Zitat Nguyen QN et al. Long-term outcomes for men with high-risk prostate cancer treated definitively with external beam radiotherapy with or without androgen deprivation. Cancer 2013;119(18):3265–71.PubMedCrossRef Nguyen QN et al. Long-term outcomes for men with high-risk prostate cancer treated definitively with external beam radiotherapy with or without androgen deprivation. Cancer 2013;119(18):3265–71.PubMedCrossRef
13.
Zurück zum Zitat Scher HI, Heller G. Clinical states in prostate cancer: toward a dynamic model of disease progression. Urology. 2000;55:323–7.PubMedCrossRef Scher HI, Heller G. Clinical states in prostate cancer: toward a dynamic model of disease progression. Urology. 2000;55:323–7.PubMedCrossRef
14.
Zurück zum Zitat Ward JF et al. The long-term clinical impact of biochemical recurrence of prostate cancer 5 or more years after radical prostatectomy. J Urol. 2003;170(5):1872–6.PubMedCrossRef Ward JF et al. The long-term clinical impact of biochemical recurrence of prostate cancer 5 or more years after radical prostatectomy. J Urol. 2003;170(5):1872–6.PubMedCrossRef
15.
Zurück zum Zitat U.S. Food and Drug Administration. FDA approves 11C-choline for PET in prostate cancer. J Nucl Med. 2012;53(12):11N. U.S. Food and Drug Administration. FDA approves 11C-choline for PET in prostate cancer. J Nucl Med. 2012;53(12):11N.
16.
Zurück zum Zitat Bouchelouche K et al. Prostate specific membrane antigen — a target for imaging and therapy with radionuclides. Discov Med. 2010;9(44):55–61.PubMedCentralPubMed Bouchelouche K et al. Prostate specific membrane antigen — a target for imaging and therapy with radionuclides. Discov Med. 2010;9(44):55–61.PubMedCentralPubMed
17.
Zurück zum Zitat Afshar-Oromieh A et al. Comparison of PET imaging with a (68)Ga-labelled PSMA ligand and (18)F-choline-based PET/CT for the diagnosis of recurrent prostate cancer. Eur J Nucl Med Mol Imaging. 2014;41(1):11–20.PubMedCentralPubMedCrossRef Afshar-Oromieh A et al. Comparison of PET imaging with a (68)Ga-labelled PSMA ligand and (18)F-choline-based PET/CT for the diagnosis of recurrent prostate cancer. Eur J Nucl Med Mol Imaging. 2014;41(1):11–20.PubMedCentralPubMedCrossRef
18.
Zurück zum Zitat Yu CY et al. Comparative performance of PET tracers in biochemical recurrence of prostate cancer: a critical analysis of literature. Am J Nucl Med Mol Imaging. 2014;4(6):580–601.PubMedCentralPubMed Yu CY et al. Comparative performance of PET tracers in biochemical recurrence of prostate cancer: a critical analysis of literature. Am J Nucl Med Mol Imaging. 2014;4(6):580–601.PubMedCentralPubMed
19.
Zurück zum Zitat Giovacchini G et al. Prostate-specific antigen velocity versus prostate-specific antigen doubling time for prediction of 11C choline PET/CT in prostate cancer patients with biochemical failure after radical prostatectomy. Clin Nucl Med. 2012;37(4):325–31.PubMedCrossRef Giovacchini G et al. Prostate-specific antigen velocity versus prostate-specific antigen doubling time for prediction of 11C choline PET/CT in prostate cancer patients with biochemical failure after radical prostatectomy. Clin Nucl Med. 2012;37(4):325–31.PubMedCrossRef
20.
Zurück zum Zitat Heidenreich A et al. EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant prostate cancer. Eur Urol. 2014;65(2):467–79.PubMedCrossRef Heidenreich A et al. EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant prostate cancer. Eur Urol. 2014;65(2):467–79.PubMedCrossRef
21.
Zurück zum Zitat Fosså SD et al. The treatment of advanced metastatic seminoma: experience in 55 cases. J Clin Oncol. 1987;5(7):1071–7.PubMed Fosså SD et al. The treatment of advanced metastatic seminoma: experience in 55 cases. J Clin Oncol. 1987;5(7):1071–7.PubMed
22.
Zurück zum Zitat Herr HW, Bosl G. Residual mass after chemotherapy for seminoma: changing concepts of management. J Urol. 1987;137(6):1234–5.PubMed Herr HW, Bosl G. Residual mass after chemotherapy for seminoma: changing concepts of management. J Urol. 1987;137(6):1234–5.PubMed
23.
Zurück zum Zitat Hofmockel G et al. Chemotherapy in advanced seminoma and the role of postcytostatic retroperitoneal lymph node dissection. Urol Int. 1996;57(1):38–42.PubMedCrossRef Hofmockel G et al. Chemotherapy in advanced seminoma and the role of postcytostatic retroperitoneal lymph node dissection. Urol Int. 1996;57(1):38–42.PubMedCrossRef
24.
Zurück zum Zitat Kamat MR et al. Value of retroperitoneal lymph node dissection in advanced testicular seminoma. J Surg Oncol. 1992;51(1):65–7.PubMedCrossRef Kamat MR et al. Value of retroperitoneal lymph node dissection in advanced testicular seminoma. J Surg Oncol. 1992;51(1):65–7.PubMedCrossRef
25.
Zurück zum Zitat Loehrer PJ et al. Chemotherapy of metastatic seminoma: The Southeastern Cancer Study Group experience. J Clin Oncol. 1987;5(8):1212–20.PubMed Loehrer PJ et al. Chemotherapy of metastatic seminoma: The Southeastern Cancer Study Group experience. J Clin Oncol. 1987;5(8):1212–20.PubMed
26.
Zurück zum Zitat Motzer R et al. Residual mass: an indication for further therapy in patients with advanced seminoma following systemic chemotherapy. J Clin Oncol. 1987;5(7):1064–70.PubMed Motzer R et al. Residual mass: an indication for further therapy in patients with advanced seminoma following systemic chemotherapy. J Clin Oncol. 1987;5(7):1064–70.PubMed
27.
Zurück zum Zitat Peckham MJ et al. Advanced seminoma: treatment with cis-platinum-based combination chemotherapy or carboplatin (JM8). Br J Cancer. 1985;52(1):7–13.PubMedCentralPubMedCrossRef Peckham MJ et al. Advanced seminoma: treatment with cis-platinum-based combination chemotherapy or carboplatin (JM8). Br J Cancer. 1985;52(1):7–13.PubMedCentralPubMedCrossRef
28.
Zurück zum Zitat De Santis M et al. 2-18fluoro-deoxy-D-glucose positron emission tomography is a reliable predictor for viable tumor in postchemotherapy seminoma: an update of the prospective multicentric SEMPET trial. J Clin Oncol. 2004;22(6):1034–9.PubMedCrossRef De Santis M et al. 2-18fluoro-deoxy-D-glucose positron emission tomography is a reliable predictor for viable tumor in postchemotherapy seminoma: an update of the prospective multicentric SEMPET trial. J Clin Oncol. 2004;22(6):1034–9.PubMedCrossRef
Metadaten
Titel
PET/CT in der Tumornachsorge
Vielversprechendes Diagnostikum für urologische Tumoren
verfasst von
Dr. med. Julius van Essen
David Pfister
Axel Heidenreich
Publikationsdatum
09.12.2014
Verlag
Urban & Vogel
Erschienen in
Uro-News / Ausgabe 12/2014
Print ISSN: 1432-9026
Elektronische ISSN: 2196-5676
DOI
https://doi.org/10.1007/s00092-014-0512-1

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