Virchows Archiv

In this issue

Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?

Danny Jonigk, Christopher Werlein, Till Acker, Martin Aepfelbacher, Kerstin U. Amann, Gustavo Baretton, Peter Barth, Rainer M. Bohle, Andreas Büttner, Reinhard Büttner, Reinhard Dettmeyer, Philip Eichhorn, Sefer Elezkurtaj, Irene Esposito, Katja Evert, Matthias Evert, Falko Fend, Nikolaus Gaßler, Stefan Gattenlöhner, Markus Glatzel, Heike Göbel, Elise Gradhand, Torsten Hansen, Arndt Hartmann, Axel Heinemann, Frank L. Heppner, Julia Hilsenbeck, David Horst, Jan C. Kamp, Gita Mall, Bruno Märkl, Benjamin Ondruschka, Jessica Pablik, Susanne Pfefferle, Alexander Quaas, Helena Radbruch, Christoph Röcken, Andreas Rosenwald, Wilfried Roth, Martina Rudelius, Peter Schirmacher, Julia Slotta-Huspenina, Kevin Smith, Linna Sommer, Konrad Stock, Philipp Ströbel, Stephanie Strobl, Ulf Titze, Gregor Weirich, Joachim Weis, Martin Werner, Claudia Wickenhauser, Thorsten Wiech, Peter Wild, Tobias Welte, Saskia von Stillfried, Peter Boor

Tumor budding and fibrotic focus—proposed grading system for tumor budding in invasive carcinoma no special type of the breast

Miyuki Hiratsuka, Takahiro Hasebe, Yuki Ichinose, Ayaka Sakakibara, Akihiro Fujimoto, Noriko Wakui, Satomi Shibasaki, Masataka Hirasaki, Masanori Yasuda, Akemi Nukui, Hiroko Shimada, Hideki Yokogawa, Kazuo Matsuura, Takashi Hojo, Akihiko Osaki, Toshiaki Saeki

Immunohistochemistry subtyping of urothelial carcinoma is feasible in the daily practice

Francisco Javier Queipo, Gorka Muñiz Unamunzaga, Begoña Fuertes Negro, Sandra Gracia Fuertes, Marina Álvarez Cortés, Elena Carceller Tejedor, Carmen María Bernal Mañas, Arceli Bono Ariño, Gottfrid Sjödahl, Carmen Beorlegui

The cytokeratin 17 expression in primary ovarian tumors has diagnostic but not prognostic significance

Pavel Dundr, Barbora Bazalová, Michaela Bártů, Tjalling Bosse, Jana Drozenová, Pavel Fabian, Oluwole Fadare, Jitka Hausnerová, Radek Jakša, Jan Laco, Sigurd F. Lax, Radoslav Matěj, W. Glenn McCluggage, Gábor Méhes, Romana Michálková, Kristýna Němejcová, Naveena Singh, Simona Stolnicu, Petr Škapa, Marián Švajdler, Ivana Stružinská

Germ cell tumors with neuroglial differentiation do not show molecular features akin to their central nervous system counterpart: experience from extra-gynecological sites

Debajyoti Chatterjee, Geethanjali Gude, Ram Samujh, Uttam Kumar Mete, Bishan Radotra

Assessing the prognostic value of tumor-infiltrating CD57+ cells in advanced stage head and neck cancer using QuPath digital image analysis

Emma J. de Ruiter, Sangeeta K. Bisheshar, Reinout H. de Roest, Frederik W. R. Wesseling, Frank J. P. Hoebers, Mari F. C. M. van den Hout, C. René Leemans, Ruud H. Brakenhoff, Remco de Bree, Chris H. J. Terhaard, Stefan M. Willems

Micro-RNA-215 and -375 regulate thymidylate synthase protein expression in pleural mesothelioma and mediate epithelial to mesenchymal transition

Francesca Napoli, Ida Rapa, Stefania Izzo, Angelica Rigutto, Roberta Libener, Chiara Riganti, Paolo Bironzo, Riccardo Taulli, Mauro Papotti, Marco Volante, Giorgio Scagliotti, Luisella Righi

Diagnostic accuracy of calretinin and acetylcholinesterase staining of rectal suction biopsies in Hirschsprung disease examined by unexperienced pathologists

L. Beltman, J. D. Windster, J. J. T. H. Roelofs, J. P. van der Voorn, J. P. M. Derikx, R. Bakx

Decreased ARG1 expression as an adverse prognostic phenotype in non-alcoholic non-virus-related hepatocellular carcinoma

Yasuyuki Shigematsu, Gulanbar Amori, Hiroaki Kanda, Yu Takahashi, Yutaka Takazawa, Kengo Takeuchi, Kentaro Inamura

MCL1 as putative target in pancreatoblastoma

Timm M. Reissig, Sebastian Uhrig, Philipp J. Jost, Claudio Luchini, Caterina Vicentini, Sven-Thorsten Liffers, Michael Allgäuer, Volkan Adsay, Aldo Scarpa, Rita Teresa Lawlor, Stefan Fröhling, Albrecht Stenzinger, Günter Klöppel, Hans-Ulrich Schildhaus, Jens T. Siveke

Cancerization of ducts in hilar cholangiocarcinoma

Jae W. Lee, Yang Zhang, Tadashi Yoshizawa, Pedram Argani, Laura D. Wood, Kiyoko Oshima

Plasmablastic myeloma in Taiwan frequently presents with extramedullary and extranodal mass mimicking plasmablastic lymphoma

Bo-Jung Chen, Chang-Tsu Yuan, Ching-Fen Yang, Chung-Han Ho, Yen-Kuang Lin, Ying-Zhen Su, Hsiu-Chu Chou, Shih-Sung Chuang

Substantial improvement of histopathological diagnosis by whole-slide image-based remote consultation

Shizu Shinohara, Andrey Bychkov, Jijgee Munkhdelger, Kishio Kuroda, Han-Seung Yoon, Shota Fujimura, Kazuhiro Tabata, Bungo Furusato, Daisuke Niino, Shinpei Morimoto, Takashi Yao, Tomoo Itoh, Hajime Aoyama, Naoko Tsuyama, Yoshiki Mikami, Toshitaka Nagao, Tohru Ikeda, Noriyoshi Fukushima, Oi Harada, Takako Kiyokawa, Naoki Yoshimi, Shinichi Aishima, Ichiro Maeda, Ichiro Mori, Koji Yamanegi, Koichi Tsuneyama, Ryohei Katoh, Miki Izumi, Yoshinao Oda, Junya Fukuoka

Sarcomatoid mesothelioma originating from mesothelioma in situ: are methylthioadenosine phosphorylase loss and CDKN2A homozygous deletion poor prognostic factors for preinvasive mesothelioma?

Megumi Nishikubo, Naoe Jimbo, Yugo Tanaka, Motoko Tachihara, Tomoo Itoh, Yoshimasa Maniwa

Coamplification of 12q15 and 12p13 and homozygous CDKN2A/2B deletion: synergistic role of fibrosarcomatous transformation in dermatofibrosarcoma protuberans with a cryptic COL1A1-PDGFB fusion

Yang Lu, Tao Li, Min Chen, Heng Peng, Tianhai Du, Yan Qiu, Hongying Zhang

Endometrial giant cell carcinoma: new insights from a morphological, immunohistochemical, and molecular analysis of three cases

Damiano Arciuolo, Antonio Travaglino, Antonio Raffone, Angela Santoro, Gianluca Russo, Angelo Minucci, Frediano Inzani, Antonio Mollo, Luigi Pedone Anchora, Francesco Fanfani, Luigi Insabato, Gian Franco Zannoni

The frequency of HER2 amplification and the percentage of membrane staining in HER2 2 + invasive carcinomas of the breast

Andrew H. S. Lee, Ian O. Ellis

Reply to letter to the editor by Lee et al.

António Polónia, Carolina Canelas, Ana Caramelo

Correction to: Micro-RNA-215 and -375 regulate thymidylate synthase protein expression in pleural mesothelioma and mediate epithelial to mesenchymal transition

Francesca Napoli, Ida Rapa, Stefania Izzo, Angelica Rigutto, Roberta Libener, Chiara Riganti, Paolo Bironzo, Riccardo Taulli, Mauro Papotti, Marco Volante, Giorgio Scagliotti, Luisella Righi