Zum Inhalt

Virchows Archiv

Ausgabe 3/2025

Inhalt (26 Artikel)

Claudin-18.2 immunohistochemical evaluation in pancreatic cancer specimens: review and recommendations for routine testing and scoring

  • Open Access
  • REVIEW

Claudio Luchini, Kristina A. Matkowskyj, Takeshi Kuwata, Teri A. Longacre, Peter Schirmacher, Manabu Takamatsu, Josef Rüschoff, Matteo Fassan

EPM2 AIP1 immunohistochemistry as a surrogate of promoter methylation analysis in endometrial carcinoma

  • Open Access
  • ORIGINAL ARTICLE

Sonia Gatius, Marta Vaquero, Oliver Scheiber, Ana Velasco, Dolors Cuevas, Karl Kashofer, Maria Santacana, Núria Eritja, Sigurd Lax, Xavier Matias-Guiu

Small cell carcinoma with rhabdomyosarcomatous differentiation of the urinary bladder: an integrated clinicopathological and molecular characterization of five cases

  • ORIGINAL ARTICLE

Ming Zhao, Ping Zhang, Jiayun Xu, Suying Wang, Yinzhou Shi, Lin Ye, Xiaomin Xu, Xiaodong Teng

Perforin-2 is overexpressed in Kikuchi-Fujimoto disease

  • ORIGINAL ARTICLE

Kirill A. Lyapichev, L. Jeffrey Medeiros, Narittee Sukswai, Siok Bian Ng, Salwa S. Sheikh, Samir Amr, Noula D. Shembade, Joseph D. Khoury

Atypical and worrisome histological features in pleomorphic adenoma: challenging and potentially significant diagnostic pitfall

  • ORIGINAL ARTICLE

Reydson Alcides de Lima-Souza, Klára Bělohlávková, Michal Michal, Albina Altemani, Fernanda Viviane Mariano, Alena Skálová

Correlation between p53 immunoexpression and TP53 mutation status in extrapulmonary small cell neuroendocrine carcinomas and its association with patient survival

  • Open Access
  • ORIGINAL ARTICLE

Klára Pavlíčková, Jan Hojný, Petr Waldauf, Pavel Dundr, Nikola Hájková, Marián Švajdler, Pavel Fabian, Iva Staniczková Zambo, Miroslava Flídrová, Jan Laco, Helena Hornychová, Patricie Delongová, Jozef Škarda, Jan Hrudka, Radoslav Matěj

Indirect clinical validation for predictive biomarkers in oncology: International Quality Network for Pathology (IQN Path) Position Paper

  • Open Access
  • ORIGINAL ARTICLE

Emina E. Torlakovic, Raed Al Dieri, Tony Badrick, Zongming Eric Chen, Carol C. Cheung, Zandra Deans, Andrew Dodson, Francesca Fenizia, Hiroshi Kijima, Joerg Maas, Antonio Martinez, Søren Nielsen, Simon Patton, Etienne Rouleau, Peter Schirmacher, Tanuja Shet, Tracy Stockley, Nicola Normanno

Pulmonary plasma cell disorders: histopathology, diagnosis, and clinical perspectives

  • Open Access
  • ORIGINAL ARTICLE

Federica Pezzuto, Giordano Fiorentù, Gioele Castelli, Simone Zanella, Chiara Giraudo, Marianerica Tinè, Fiorella Calabrese

Angiomatoid fibrous histiocytoma occurring at distal/acral extremity sites: clinicopathological and molecular study of 26 cases highlighting frequent myxoid histology and site-dependent genotypic variation

  • Open Access
  • ORIGINAL ARTICLE

Abbas Agaimy, Jeremy Molligan, Fatimah I. Alruwaii, Cristina R. Antonescu, Elizabeth G. Demicco, Brendan C. Dickson, John Gross, Michael Michal, Kyle Perry, Lars Tögel, Robert Stoehr, Nasir Ud Din, Andrew L. Folpe

Hybrid granular cell tumor/perineurioma: a report of two rare cases with PIK3CA mutations

  • ORIGINAL ARTICLE

Ani Toklu, Gauri Panse, George Jour, Konstantinos Linos, Jeffrey M. Cloutier, Carina A. Dehner

Evaluation of PD-L1, TERT promoter mutations, and BRAFV600E mutation in poorly differentiated, differentiated high grade thyroid carcinoma and anaplastic carcinoma of the thyroid: our institutional experience

  • ORIGINAL ARTICLE

Alessia Piermattei, Giuseppe Migliara, Angela Feraco, Carmine Bruno, Luisa Cioni, Qianqian Zhang, Belen Padial-Urtueta, Elisabetta Merenda, Guido Fadda, Marco Raffaelli, Luigi Maria Larocca, Antonino Mule, Alfredo Pontecorvi, Esther Diana Rossi

Acantholytic squamous cell carcinoma of the lung with pseudoglandular features: clinicopathologic study of 14 cases

  • ORIGINAL ARTICLE

David I. Suster, A. Craig Mackinnon, Haider A. Mejbel, Saul Suster

Prostatic amyloidosis: pathological features of an underdiagnosed condition

  • ORIGINAL ARTICLE

José A. Ortiz-Rey, Jorge Sánchez-Ramos, Samer Abdulkader-Sande, David Muñoz-Raya, José Aguayo-Arjona, Alfonso Fernández-Costas, Carolina Gómez-de María, Lourdes Liste-Tizón, Edgar J. Escalona-Canal, Sergio Raposeiras-Roubín, Rafael J. Cobas-Paz, Pilar San Miguel-Fraile, Enrique Cespón-Outeda, María Cespón-Fernández

FOXA1 expression and its association with mucin expression and KRAS mutation in ovarian mucinous tumors: implications for tumor progression and differentiation

  • ORIGINAL ARTICLE

Men Yuan, Harumi Saeki, Takuo Hayashi, Yoshiya Horimoto, Kazunari Fujino, Yasuhisa Terao, Takashi Yao

Correlation between TP53 mutational status and digital quantification of p53 immunohistochemistry in mantle cell lymphoma

  • ORIGINAL ARTICLE

Mingfei Yan, Shenon Sethi, Zachary Epstein-Peterson, Anita Kumar, Ahmet Dogan, Pallavi Galera

A practical approach to better identify NTRK 1–3 fusion-positive mesenchymal neoplasms by pan-Trk immunohistochemistry

  • Open Access
  • ORIGINAL ARTICLE

Martina Haberecker, Pauline Kuerten, Viola Katharina Vetter, Francesca Malega, Holger Moch, Chantal Pauli

Coccoid Helicobacter pylori in patients with obesity: an immunohistochemical study

  • Open Access
  • ORIGINAL ARTICLE

Chen Mayer, Daniel Hillel, Iris Barshack, Michael Schvimer

Tumor-infiltrating plasma cells are a prognostic factor in penile squamous cell carcinoma

  • Open Access
  • ORIGINAL ARTICLE

P. J. Stenzel, A. Thomas, M. Schindeldecker, S. Macher-Goeppinger, S. Porubsky, A. Haferkamp, I. Tsaur, W. Roth, K. E. Tagscherer

Prognostic impact of fibrosclerotic changes in non-papillary, non-anaplastic, follicular cell-derived thyroid carcinomas

  • Open Access
  • ORIGINAL ARTICLE

Giulia Orlando, Giulia Capella, Giulia Vocino Trucco, Elena Vissio, Jasna Metovic, Francesca Maletta, Marco Volante, Mauro Papotti

Correspondence—answer to letter VIAR-D-25–00371

  • Open Access
  • LETTER TO THE EDITOR

Marit Bernhardt, Benjamin Aretz, Glen Kristiansen

Correction to: Succinate dehydrogenase defcient renal cell carcinoma frequently expresses GATA3 and L1CAM

  • Correction

Ankur R. Sangoi, Sean R. Williamson, Murat Oktay, Anthony J. Gill, Kiril Trpkov, Farshid Siadat, Fiona MacLean, Laurence A. Galea, Dilek Ertoy Baydar, Caglar Cakir, Yasemin Yuyucu Karabulut, Deniz Baycelebi, Ganime Coban, Banu Sarsik, Busra Yaprak Bayrak, Levente Kuthi, Boglarka Posfai, Aysha Mobeen, Sambit K. Mohanty, Xulang Zhang, Mohammed A. Alghamdi, Liang Cheng, Michelle S. Hirsch, Mahmut Akgul

Neu im Fachgebiet Pathologie

Fabrizierte und/oder Induzierte Krankheit und medizinische Kindesmisshandlung

Fabrizierte und/oder Induzierte Krankheit (FII, ehemals Münchhausen-by-Proxy-Syndrom)/medizinische Kindesmisshandlung (MKM) ist eine Form der Kindesmisshandlung, bei der ein Kind oder Jugendliche*r unter 18 Jahren durch Handlungen einer …

Forensisch-medizinische körperliche Untersuchung von Mädchen und Jungen bei Verdacht auf Misshandlung und Missbrauch

1 Einleitung 2 Zielsetzung der Empfehlung 3 Grundsätze zum Umgang mit unterschiedlichen Settings/Auftraggebern und Zuweisern 3.1 Konsiliarische Mitbeurteilungen 3.2 Verletzungseinschätzungen für Jugendämter 3.3 Ermittlungsbehörden 3.4 Sonderfall …

Leibzeichen in Norddeutschland – ein (fast) vergessener Rechtsbrauch

In nordeuropäischen Kirchen werden – meistens im Rahmen von Baumaßnahmen – immer wieder menschliche Überreste entdeckt; diese befinden sich oft in mumifiziertem Zustand, und ihr Ursprung ist weitgehend unbekannt. Zu der Herkunft dieser Relikte – …

Präneoplasien des hepatozellulären Karzinoms

Das hepatozelluläre Karzinom (HCC) entsteht meist auf dem Boden einer Leberzirrhose. Häufige Risikofaktoren sind virale Hepatitiden B/C, Alkoholabusus, „metabolic dysfunction associated steatotic liver disease“ (MASLD) und genetische Erkrankungen.