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Virchows Archiv

Ausgabe 5/2024

Inhalt (21 Artikel)

Familial syndromes associated with testicular and paratesticular neoplasms: a comprehensive review

  • REVIEW AND PERSPECTIVES

Andrea Strakova-Peterikova, Maryna Slisarenko, Josef Skopal, Kristyna Pivovarcikova, Tomas Pitra, Mihaela Farcas, Michael Michal, Michal Michal, Kvetoslava Michalova

Poorly differentiated thyroid carcinomas: conceptual controversy and clinical impact

  • Review and Perspectives

Andrés Coca-Pelaz, Juan P. Rodrigo, Abbas Agaimy, Michelle D. Williams, Nabil F. Saba, Sandra Nuyts, Gregory W. Randolph, Fernando López, Vincent Vander Poorten, Luiz P. Kowalski, Francisco J. Civantos, Mark E. Zafereo, Antti A. Mäkitie, Oded Cohen, Iain J. Nixon, Alessandra Rinaldo, Alfio Ferlito

Redefining and capturing pre-analytic deficiencies in an anatomical pathology laboratory: a quality improvement initiative

  • Original Article

Tra Truong, Preeya Roopchard, Ekaterina Olkhov-Mitsel, Armin Farahvash, Gail Sanders, Tanya Jordan, Zeina Ghorab, Elzbieta Slodkowska, Michelle R. Downes

Three-dimensional analysis of ductular reactions and their correlation with liver regeneration and fibrosis

  • ORIGINAL ARTICLE

Tadashi Yoshizawa, Jae W. Lee, Seung-Mo Hong, DongJun Jung, Michaël Noë, Wojciech Zbijewski, Ashley Kiemen, Pei-Hsun Wu, Denis Wirtz, Ralph H. Hruban, Laura D. Wood, Kiyoko Oshima

The value of GLI1 and p16 immunohistochemistry in the premolecular screening for GLI1-altered mesenchymal neoplasms

  • Original Article

Isidro Machado, Abbas Agaimy, Francisco Giner, Samuel Navarro, Michael Michal, Julia Bridge, Reyes Claramunt, José Antonio López-Guerrero, Javier Alcacer, Konstantinos Linos, Antonio Llombart-Bosch

Characterization of two transcriptomic subtypes of marker-null large cell carcinoma of the lung suggests different origin and potential new therapeutic perspectives

  • Open Access
  • ORIGINAL ARTICLE

Michele Simbolo, Giovanni Centonze, Anastasios Gkountakos, Valentina Monti, Patrick Maisonneuve, Stela Golovco, Giovanna Sabella, Alessandro Del Gobbo, Stefano Gobbo, Stefano Ferrero, Alessandra Fabbri, Carlotta Pardo, Giovanna Garzone, Natalie Prinzi, Sara Pusceddu, Adele Testi, Luigi Rolli, Alessandro Mangogna, Luisa Bercich, Mauro Roberto Benvenuti, Emilio Bria, Sara Pilotto, Alfredo Berruti, Ugo Pastorino, Carlo Capella, Maurizio Infante, Michele Milella, Aldo Scarpa, Massimo Milione

Syndromic MEN1 parathyroid adenomas consist of both subclonal nodules and clonally independent tumors

  • Open Access
  • ORIGINAL ARTICLE

Konstantin Bräutigam, Cédric Nesti, Philipp Riss, Christian Scheuba, Bruno Niederle, Tobias Grob, Annunziata Di Domenico, Maja Neuenschwander, Peter Mazal, Nastassja Köhn, Roman Trepp, Aurel Perren, Reto M. Kaderli

Utility of LEF1 to differentiate desmoid fibromatosis from its histologic mimics

  • Original Article

Soma Jobbagy, Santiago Lozano-Calderon, John T. Mullen, G. Petur Nielsen, Yin P. Hung, Ivan Chebib

Perinatal arterial ischemic stroke: how informative is the placenta?

  • Open Access
  • ORIGINAL ARTICLE

Jessica Hirschel, Francisca Barcos-Munoz, François Chalard, Florence Chiodini, Manuella Epiney, Joel Fluss, Anne-Laure Rougemont

N-myc downstream–regulated gene 1 can promote vasculogenic mimicry and angiogenesis in urothelial carcinoma

  • Open Access
  • Original Article

Ereny Kamal Louis, Islam F. Abdelkawi, Abeer Refaiy, Asmaa M. Ahmed

CCN2/CTGF expression does not correlate with fibrosis in myeloproliferative neoplasms, consistent with noncanonical TGF-β signaling driving myelofibrosis

  • Open Access
  • ORIGINAL ARTICLE

Roos J. Leguit, Roel Broekhuizen, Moniek de Witte, Reinier A. P. Raymakers, Roel Goldschmeding

An unusual cytological presentation of solid pseudopapillary neoplasm of the pancreas mimicking adenoid cystic carcinoma: a case report and literature review

  • BRIEF REPORT

Yumiko Higuchi, Eishin Kurihara, Toshihiko Kato, Mei Oshima, Fuki Endo, Fuminori Sato, Tsutomu Kobatake, Masashi Ijima, Shiro Sugihara, Noriyuki Tani, Yosuke Otake, Yasuo Imai

T cell phenotype and lack of eosinophilia are not uncommon in extramedullary myeloid/lymphoid neoplasms with ETV6::FLT3 fusion: a case report and review of the literature

  • Brief Report

Jérémy Schoelinck, Julie Gervasoni, Yann Guillermin, Emmanuel Beillard, Daniel Pissaloux, Catherine Chassagne-Clement

Gastroblastoma with a novel ACTB::GLI1 gene fusion in a 19-year-old male

  • Brief Report

Junaid Shabbir, Jonathan Earle, Krzysztof Glomski, Laila Mnayer, Bret Schipper, Saverio Ligato

Inflammatory/juvenile-like polyps in neurofibromatosis type 1 associated with epithelial dysplasia

  • BRIEF REPORT

Diana Enea, Xavier Dray, Erell Guillerm, Antoine Guilloux, Matthieu Yver, Pascale Cervera, Magali Svrcek

Correction to: Tumor budding and fibrotic focus—proposed grading system for tumor budding in invasive carcinoma no special type of the breast

  • Open Access
  • Correction

Miyuki Hiratsuka, Takahiro Hasebe, Yuki Ichinose, Ayaka Sakakibara, Akihiro Fujimoto, Noriko Wakui, Satomi Shibasaki, Masataka Hirasaki, Masanori Yasuda, Akemi Nukui, Hiroko Shimada, Hideki Yokogawa, Kazuo Matsuura, Takashi Hojo, Akihiko Osaki, Toshiaki Saeki

Correction to: Claudin-10 is a new candidate prognostic marker in metastatic high-grade serous carcinoma

  • Open Access
  • Correction

Ben Davidson, Delfim Doutel, Arild Holth, Dag Andre Nymoen

Correction to: Mediastinal large B cell lymphoma and surrounding gray areas: a report of the lymphoma workshop of the 20th meeting of the European Association for Haematopathology

  • Open Access
  • Correction

Sarah E. Gibson, Stefan Dojcinov, Snjezana Dotlic, Sylvia Hartmann, Eric D. Hsi, Monika Klimkowska, Federica Melle, Stefano A. Pileri, Colleen A. Ramsower, Karen Rech, Lisa M. Rimsza, Socorro Maria Rodriguez‑Pinilla, Thomas A. Tousseyn, Daphne de Jong, Elena Sabattini

Neu im Fachgebiet Pathologie

Neuroendokrine Neoplasien

Neuroendokrine Tumoren (NET) sind eine bunte Gruppe von Neoplasien, die von neuroendokrinen Zellen im gesamten Körper ausgehen. Die NET-Diagnose stellt aufgrund ihrer vielfältigen Erscheinungsformen, Morphologie und biologischen Verhaltensweisen …

Arzneimittelreaktionen, die unter die Haut gehen

Medikamentöse Therapien können eine Vielzahl mukokutaner Nebenwirkungen hervorrufen. Dennoch geht das Spektrum exanthematischer Arzneimittelreaktionen weit über das Bild klassischer makulopapulöser Exantheme hinaus. Die Übersicht fasst häufige Präsentationen (außerhalb der allergischen Soforttypreaktionen) zusammen.

Pathologie der Milz

Nach einer Beschreibung der Milzanatomie und Darstellung der diagnostisch wichtigsten immunhistochemischen Färbungen zur Identifizierung der normalen Milzkompartimente werden am Beispiel eines nordafrikanischen Patienten mit rezentem …

Molekular definierte Nierenzellkarzinome 2025

Im Zuge der Überarbeitung der WHO-Klassifikation im Jahr 2022 konnten für mehrere Nierenzellkarzinome (NZK), die sich zuvor nicht eindeutig den bis dahin definierten Tumortypen zuordnen ließen, jedoch gemeinsame morphologische und molekulare …