Virchows Archiv

In this issue

• NEWS

The HER2-low revolution in gynecological oncology: could it be a realistic emerging challenge?

• Open Access
• COMMENTARY

Angela Santoro, Belen-Padial Urtueta, Gian Franco Zannoni

Molecularly defined sinonasal malignancies: an overview with focus on the current WHO classification and recently described provisional entities

• Open Access
• REVIEW AND PERSPECTIVES

Alena Skálová, Abbas Agaimy, Martina Bradova, Vincent Vander Poorten, Ehab Hanna, Orlando Guntinas-Lichius, Alessandro Franchi, Henrik Hellquist, Roderick H. W. Simpson, Fernando Lopéz, Sandra Nuyts, Carlos Chiesa-Estomba, Sweet Ping Ng, Akihiro Homma, Yong Teng, Ilmo Leivo, Alfio Ferlito

Comparison of the 7th and revised 8th UICC editions (2020) for oral squamous cell carcinoma: How does the reclassification impact staging and survival?

• Open Access
• ORIGINAL ARTICLE

Ann-Kristin Struckmeier, Philip Eichhorn, Abbas Agaimy, Mayte Buchbender, Tobias Moest, Rainer Lutz, Marco Kesting

Expression of fibroblast growth factor receptor 2 (FGFR2) in combined hepatocellular-cholangiocarcinoma and intrahepatic cholangiocarcinoma: clinicopathological study

• Open Access
• ORIGINAL ARTICLE

Motoko Sasaki, Yasunori Sato, Yasuni Nakanuma

Correlation of High-Grade Osteosarcoma Response to Chemotherapy with Enhanced Tissue Immunological Response: Analysis of CD95R, IFN-γ, Catalase, Hsp70, and VEGF

• Open Access
• ORIGINAL ARTICLE

Sjahjenny Mustokoweni, Ferdiansyah Mahyudin, Rosy Setiawati, Dian Nugrahenny, Mohamad Hidayat, Handono Kalim, Karyono Mintaroem, Loeki Enggar Fitri, Pancras C. W. Hogendoorn

P53 Overexpression May Represent an Early Marker of Clinicopathologic Progression in Vasculogenic Mesenchymal Lesions of Germ Cell Tumor Origin

• ORIGINAL ARTICLE

Reem Youssef, Thomas M. Ulbright, Andres M. Acosta

Expression of CD5 in salivary gland tumors: an ancillary marker for carcinoma showing thymus-like differentiation (CASTLE) of the major salivary gland

• ORIGINAL ARTICLE

Eiichi Sasaki, Hoshino Terada, Naoki Oishi, Akari Iwakoshi, Katsuhiro Masago, Hirokazu Matsushita, Hidetaka Yamamoto, Nobuhiro Hanai, Hisashi Tateyama

Lymphovascular invasion and p16 expression are independent prognostic factors in stage I vulvar squamous cell carcinoma

• Open Access
• ORIGINAL ARTICLE

Ben Davidson, Tone Skeie-Jensen, Arild Holth, Kristina Lindemann, Anne Marie Toralba Barrameda, Agnes Kathrine Lie, Yun Wang

Deep learning model to differentiate Crohn’s disease from intestinal tuberculosis using histopathological whole slide images from intestinal specimens

• Original Article

Xinning Liu, Fei Li, Jie Xu, Jinting Ma, Xiaoyu Duan, Ren Mao, Minhu Chen, Zhihui Chen, Yan Huang, Jingyi Jiang, Bingsheng Huang, Ziyin Ye

Biphasic synovial sarcoma with myoepithelial features: a distinctive variant with a predilection for the foot

• ORIGINAL ARTICLE

Shahd S. Almohsen, Anthony M. Griffin, Brendan C. Dickson, Elizabeth G. Demicco

Prognostic value of HPV-PCR, p16 and p53 immunohistochemical status on local recurrence rate and survival in patients with vulvar squamous cell carcinoma

• Open Access
• ORIGINAL ARTICLE

A. W. Pouwer, N. C. te Grootenhuis, F. Hinten, G. H. de Bock, A. G. J. van der Zee, W. J. G. Melchers, M. H. M. Oonk, J. A. de Hullu, H. Hollema, J. Bulten

Prognosis of Gleason score 8 prostatic adenocarcinoma in needle biopsies: a nationwide population-based study

• Open Access
• Original Article

Lars Egevad, Chiara Micoli, Brett Delahunt, Hemamali Samaratunga, Andri Wilberg Orrason, Hans Garmo, Pär Stattin, Martin Eklund

Analytical and clinical validation of PATHWAY Anti-HER-2/neu (4B5) antibody to assess HER2-low status for trastuzumab deruxtecan treatment in breast cancer

• Open Access
• ORIGINAL ARTICLE

Charo Garrido, Melissa Manoogian, Dhiraj Ghambire, Shawn Lucas, Maha Karnoub, Matthew T. Olson, David G. Hicks, Gary Tozbikian, Aleix Prat, Naoto T. Ueno, Shanu Modi, Wenqin Feng, Judith Pugh, Ching Hsu, Junji Tsurutani, David Cameron, Nadia Harbeck, Qijun Fang, Shirin Khambata-Ford, Xuemin Liu, Landon J. Inge, Patrik Vitazka

Uterine leiomyoma with RAD51B::NUDT3 fusion: a report of 2 cases

• Open Access
• Original Article

Pavel Dundr, Alba Machado-Lopez, Aymara Mas, Zuzana Věcková, Michal Mára, Adéla Richtárová, Radoslav Matěj, Ivana Stružinská, Michaela Kendall Bártů, Kristýna Němejcová, Jiří Dvořák, Jan Hojný

Extraskeletal chondroma of the toe in a child with DICER1 tumor predisposition syndrome: support for a dominant negative mechanism

• BRIEF REPORT

Dylan Pelletier, Nelly Sabbaghian, Anne-Laure Chong, John R. Priest, Yomna Elsheikh Ahmed, Gabriel P. Fox, Marc R. Fabian, William D. Foulkes

Wait and see: a case of EBV + cutaneous extranodal NK/T-type lymphoma with indolent behaviour

• BRIEF REPORT

Italo Francesco Aromolo, Carlo Pescia, Domenico Simeoli, Silvia Alberti Violetti, Valeria Ferla, Francesca Gaia Rossi, Giorgio Alberto Croci

Renal histiocytic fibrillary inclusions in a patient with new-onset proteinuria and monoclonal gammopathy

• BRIEF REPORT

Sanjivani Shrestha, Silvia Malvica, Samir C. Gautam, Serena Bagnasco

Correction to: P53 Overexpression May Represent an Early Marker of Clinicopathologic Progression in Vasculogenic Mesenchymal Lesions of Germ Cell Tumor Origin

• Correction

Reem Youssef, Thomas M. Ulbright, Andres M. Acosta

Correction to: Aggressive B-cell non-Hodgkin lymphomas: a report of the lymphoma workshop of the 20th meeting of the European Association for Haematopathology

• Open Access
• Correction

Socorro Maria Rodriguez-Pinilla, Stefan Dojcinov, Snjezana Dotlic, Sarah E. Gibson, Sylvia Hartmann, Monika Klimkowska, Elena Sabattini, Thomas A. Tousseyn, Daphne de Jong, Eric. D. Hsi

Correction to: Voices from the past: results of the ESP history of pathology working group survey on pathology museums

• Open Access
• Correction

Raffaella Santi, Roberta Ballestriero, Vincenzo Canzonieri, Jacek Gulczynski, Rosa Henriques de Gouveia, Aurelio Ariza, Lina Carvalho, Gabriella Nesi