Erschienen in:
26.06.2020 | Sarcoma
Virtual Biobanking for Retroperitoneal Sarcoma: A Transatlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG) Initiative
verfasst von:
Eisar Al-Sukhni, MD, MSc, Winan J. van Houdt, MD, PhD, Sally M. Burtenshaw, MSc, Yael Babichev, PhD, Chandrajit P. Raut, MD, MSc, Marco Fiore, MD, Elizabeth G. Demicco, MD, PhD, Alessandro Gronchi, MD, Rebecca A. Gladdy, MD, PhD
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 10/2020
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Excerpt
Sarcomas are rare tumors comprising more than 70 distinct histologic types. The broad spectrum of behavior of these tumors, in addition to the lack of effective standard therapeutic agents for most, are factors underlying the need for translational research in this field. Biobanking—the collection of biomaterials as well as associated clinical, pathologic, and molecular data—facilitates translational research by providing the material not only to investigate the molecular contributors of tumor pathogenesis but also to develop new treatments and investigate their effectiveness on an individual level (i.e., personalized medicine).
1 Pooling resources from multiple biobanks can further this goal by providing a larger foundation of specimens on which to build translational research.
2 For diseases, such as sarcoma, that consist of numerous rare distinct types, collaboration is critical to achieve sufficient numbers to define molecular mechanisms and to develop prognostic biomarkers. …
