Skip to main content
Erschienen in: Osteoporosis International 3/2017

26.11.2016 | Original Article

Vitamin D status in Bosnia and Herzegovina: the cross-sectional epidemiological analysis

verfasst von: S. Sokolovic, R. Alimanovic-Alagic, L. Dzananovic, S. Cavaljuga, N. Beslic, E. Ferhatbegovic-Opankovic

Erschienen in: Osteoporosis International | Ausgabe 3/2017

Einloggen, um Zugang zu erhalten

Abstract

Summary

Rationale: Vitamin D deficiency/insufficiency/ is a worldwide epidemic in general population. The investigation of vitamin D concentrations in Bosnia and Herzegovina has never been conducted. Main results: A total of 82% from 2483 examined patients have deficient/insufficient/ Vitamin D level. Significance: These results encourage future studies to be focused on more specific details.

Introduction

The goal of this paper was to evaluate the vitamin D concentrations in different cohort patients. Vitamin D deficiency is a global health problem. In Europe, hypovitaminosis D is even more prevalent. Vitamin D deficiency plays a significant role in a dozens of numerous disorders.

Methods

The cross-sectional epidemiological analysis was performed, and data were statistically analyzed. A total of 2483 screened individuals were examined for the serum 25(OH)D concentrations. The cutoff points that we used was <20 ng/mL.

Results

Among 2483 examined patients for vitamin D level, females were in majority with 76% and males with 24% in total. Deficient vitamin D level was found in 60.6% of patients, and insufficient vitamin D level was detected in 21.4%. The highest rate of severe deficiency was found among elderly people (32.9%). In total, the decreased level of vitamin D concentration in Bosnia and Herzegovina is 82%.

Conclusions

Vitamin D serum concentrations in Bosnia and Herzegovina are decreased in a majority of study population, and the results are within the average levels compared to other countries, particularly to findings in Central Europe.
This analysis was based on patients, who have some health issues which may affect mobility, ability to go outside, food intake etc., so the level of 25(OH)D seen in this paper may be an underestimate, and further research is required in the general and healthy population.
Literatur
1.
Zurück zum Zitat Alkerwi A, Sauvageot N, Gilson G, Stranges S (2015) Prevalence and correlates of vitamin D deficiency and insufficiency in Luxembourg adults: evidence from the observation of cardiovascular risk factors (ORISCAV-LUX) study. Nutrients 7(8):6780–6796CrossRefPubMedPubMedCentral Alkerwi A, Sauvageot N, Gilson G, Stranges S (2015) Prevalence and correlates of vitamin D deficiency and insufficiency in Luxembourg adults: evidence from the observation of cardiovascular risk factors (ORISCAV-LUX) study. Nutrients 7(8):6780–6796CrossRefPubMedPubMedCentral
2.
Zurück zum Zitat Spiro A, Buttriss JL (2014) Vitamin D: an overview of vitamin D status and intake in Europe. Nutr Bull BNF 39:322–350CrossRef Spiro A, Buttriss JL (2014) Vitamin D: an overview of vitamin D status and intake in Europe. Nutr Bull BNF 39:322–350CrossRef
3.
Zurück zum Zitat Lips P (2010) Worldwide status of vitamin D nutrition. J Steroid Biochem Mol Biol 121:297–300CrossRefPubMed Lips P (2010) Worldwide status of vitamin D nutrition. J Steroid Biochem Mol Biol 121:297–300CrossRefPubMed
5.
Zurück zum Zitat Gordon CM, de Peter KC, Feldman HA et al (2004) Prevalence of vitamin D deficiency among healthy adolescents. Arch Pediatr Adolesc Med 158:531–537CrossRefPubMed Gordon CM, de Peter KC, Feldman HA et al (2004) Prevalence of vitamin D deficiency among healthy adolescents. Arch Pediatr Adolesc Med 158:531–537CrossRefPubMed
6.
Zurück zum Zitat Vanderwielen RPJ, Lowik MRH, Vandenberg H et al (1995) Serum vitamin D concentrations among elderly people in Europe. Lancet 346:207–210CrossRef Vanderwielen RPJ, Lowik MRH, Vandenberg H et al (1995) Serum vitamin D concentrations among elderly people in Europe. Lancet 346:207–210CrossRef
7.
Zurück zum Zitat Holick MF, Shao Q, Liu W, Chen T (1992) The vitamin D content of fortified milk and infant formula. N Engl J Med 326:1178–1181CrossRefPubMed Holick MF, Shao Q, Liu W, Chen T (1992) The vitamin D content of fortified milk and infant formula. N Engl J Med 326:1178–1181CrossRefPubMed
8.
Zurück zum Zitat Holick MF (2004) Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr 79(890):362–371CrossRefPubMed Holick MF (2004) Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr 79(890):362–371CrossRefPubMed
9.
Zurück zum Zitat Holick MF (2006) High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc 81(3):353–373CrossRefPubMed Holick MF (2006) High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc 81(3):353–373CrossRefPubMed
10.
Zurück zum Zitat Lips P (2007) Vitamin D status and nutrition in Europe and Asia. J Steroid Biochem Mol Biol 103:620–625CrossRefPubMed Lips P (2007) Vitamin D status and nutrition in Europe and Asia. J Steroid Biochem Mol Biol 103:620–625CrossRefPubMed
11.
Zurück zum Zitat Snijder MB, van Dam RM, Visser M et al (2005) Adiposity in relation to vitamin D status and parathyroid hormone levels: a population-based study in older men and women. J Clin Endocrinol Metab 90:4119–4123CrossRefPubMed Snijder MB, van Dam RM, Visser M et al (2005) Adiposity in relation to vitamin D status and parathyroid hormone levels: a population-based study in older men and women. J Clin Endocrinol Metab 90:4119–4123CrossRefPubMed
12.
Zurück zum Zitat van Dam RM, Snijder MB, Dekker JM et al (2007) Potentially modifiable determinants of vitamin D status in an older population in the Netherlands: the Hoorn Study. Am J Clin Nutr 85:755–761CrossRefPubMed van Dam RM, Snijder MB, Dekker JM et al (2007) Potentially modifiable determinants of vitamin D status in an older population in the Netherlands: the Hoorn Study. Am J Clin Nutr 85:755–761CrossRefPubMed
13.
Zurück zum Zitat Burnand B, Sloutskis D, Gianoli F et al (1992) Serum 25-hydroxyvitamin D: distribution and determinants in the Swiss population. Am J Clin Nutr 56:537–542CrossRefPubMed Burnand B, Sloutskis D, Gianoli F et al (1992) Serum 25-hydroxyvitamin D: distribution and determinants in the Swiss population. Am J Clin Nutr 56:537–542CrossRefPubMed
14.
Zurück zum Zitat Bettica P, Bevilacqua M, Vago T, Norbiato G (1999) High prevalence of hypovitaminosis D among free-living postmenopausal women referred to an osteoporosis outpatient clinic in northern Italy for initial screening. Osteoporos Int 9:226–229CrossRefPubMed Bettica P, Bevilacqua M, Vago T, Norbiato G (1999) High prevalence of hypovitaminosis D among free-living postmenopausal women referred to an osteoporosis outpatient clinic in northern Italy for initial screening. Osteoporos Int 9:226–229CrossRefPubMed
15.
Zurück zum Zitat Isaia G, Giorgino R, Rini GB et al (2003) Prevalence of hypovitaminosis D in elderly women in Italy: clinical consequences and risk factors. Osteoporos Int 14:577–582CrossRefPubMed Isaia G, Giorgino R, Rini GB et al (2003) Prevalence of hypovitaminosis D in elderly women in Italy: clinical consequences and risk factors. Osteoporos Int 14:577–582CrossRefPubMed
16.
Zurück zum Zitat Quesada JM, Jans I, Benito P et al (1989) Vitamin D status of elderly people in Spain. Age Ageing 18:392–397CrossRefPubMed Quesada JM, Jans I, Benito P et al (1989) Vitamin D status of elderly people in Spain. Age Ageing 18:392–397CrossRefPubMed
17.
Zurück zum Zitat Challa A, Ntourntoufi A, Cholevas V et al (2005) Breastfeeding and vitamin D status in Greece during the first 6 months of life. Eur J Pediatr 164:724–729CrossRefPubMed Challa A, Ntourntoufi A, Cholevas V et al (2005) Breastfeeding and vitamin D status in Greece during the first 6 months of life. Eur J Pediatr 164:724–729CrossRefPubMed
18.
Zurück zum Zitat Lapatsanis D, Moulas A, Cholevas V et al (2005) Vitamin D: a necessity for children and adolescents in Greece. Calcif Tissue Int 77:348–355CrossRefPubMed Lapatsanis D, Moulas A, Cholevas V et al (2005) Vitamin D: a necessity for children and adolescents in Greece. Calcif Tissue Int 77:348–355CrossRefPubMed
19.
Zurück zum Zitat Povoroznyuk VV, Balatska NI, Muts VY et al (2012) Vitamin D deficiency in Ukraine: a demographic and seasonal analysis. Gerontologija 13(4):191–198 Povoroznyuk VV, Balatska NI, Muts VY et al (2012) Vitamin D deficiency in Ukraine: a demographic and seasonal analysis. Gerontologija 13(4):191–198
20.
Zurück zum Zitat Chapuy MC, Preziosi P, Maamer M et al (1997) Prevalence of vitamin D insufficiency in an adult normal population. Osteoporos Int 7:439–443CrossRefPubMed Chapuy MC, Preziosi P, Maamer M et al (1997) Prevalence of vitamin D insufficiency in an adult normal population. Osteoporos Int 7:439–443CrossRefPubMed
21.
Zurück zum Zitat Brouwer-Brolsma EM, Vaes AM, van der Zwaluw NL, et al. (2015) Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study. J Steroid Biochem Mol Biol. (in print) Brouwer-Brolsma EM, Vaes AM, van der Zwaluw NL, et al. (2015) Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study. J Steroid Biochem Mol Biol. (in print)
22.
Zurück zum Zitat Ross AC, Manson JE, Abrams SA et al (2011) The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab 96:53–58CrossRefPubMed Ross AC, Manson JE, Abrams SA et al (2011) The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab 96:53–58CrossRefPubMed
23.
Zurück zum Zitat Hilger J, Friedel A, Herr R et al (2013) A systemic review of vitamin D status in population worldwide. Br J Nutr 1-3 Hilger J, Friedel A, Herr R et al (2013) A systemic review of vitamin D status in population worldwide. Br J Nutr 1-3
24.
25.
Zurück zum Zitat Povoroznyuk V (2012) Epidemiology of vit. D deficiency in Ukraine: oral presentation during: Vitamin D- minimum, maximum, optimum, Warsaw Povoroznyuk V (2012) Epidemiology of vit. D deficiency in Ukraine: oral presentation during: Vitamin D- minimum, maximum, optimum, Warsaw
26.
Zurück zum Zitat Al W, Cooper C, Ebeling PR et al (2012) A global representation of vitamin D health status in healthy pupulation. Arch Osteop 7:155–172CrossRef Al W, Cooper C, Ebeling PR et al (2012) A global representation of vitamin D health status in healthy pupulation. Arch Osteop 7:155–172CrossRef
27.
Zurück zum Zitat Pludowski P, Karczmarewicz E, Bayer M et al (2013) Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe—recommendation of vitamin D intakes in the general population and groups at risk for vitamin D deficiency. Endokrinologya Polska 64(3) Pludowski P, Karczmarewicz E, Bayer M et al (2013) Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe—recommendation of vitamin D intakes in the general population and groups at risk for vitamin D deficiency. Endokrinologya Polska 64(3)
Metadaten
Titel
Vitamin D status in Bosnia and Herzegovina: the cross-sectional epidemiological analysis
verfasst von
S. Sokolovic
R. Alimanovic-Alagic
L. Dzananovic
S. Cavaljuga
N. Beslic
E. Ferhatbegovic-Opankovic
Publikationsdatum
26.11.2016
Verlag
Springer London
Erschienen in
Osteoporosis International / Ausgabe 3/2017
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-016-3831-0

Weitere Artikel der Ausgabe 3/2017

Osteoporosis International 3/2017 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.