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01.12.2015

Vitamin D Status in South Africa and Tuberculosis

verfasst von: Abhimanyu, Vanessa Meyer, Tamsyn Jacki Jeffery, Liza Bornman

Erschienen in: Lung | Ausgabe 6/2015

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Abstract

According to the World Health Organisation South Africa has the third highest tuberculosis (TB) incidence in the world, with an estimated 60 % incident cases having both TB and HIV. The South African National Tuberculosis Association (SANTA) recognized the importance of nutrition in the prevention and management of TB by including feeding schemes in community outreach programs. Vitamin D enhances innate immunity against mycobacterial infection through the antimicrobial peptide, cathelicidin. We reviewed studies on vitamin D status, its link with TB, and potential use in therapy in multiethnic South Africa with sunlight as primary source of vitamin D. Ethnicity, season, disease state, latitude, and urbanization are critical factors to be considered in vitamin D supplementation for prevention and treatment of TB.

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Titel: Vitamin D Status in South Africa and Tuberculosis
verfasst von: Abhimanyu
Vanessa Meyer
Tamsyn Jacki Jeffery
Liza Bornman
Publikationsdatum: 01.12.2015
Verlag: Springer US
Erschienen in: Lung / Ausgabe 6/2015
Print ISSN: 0341-2040
Elektronische ISSN: 1432-1750
DOI: https://doi.org/10.1007/s00408-015-9789-4

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Vitamin D Status in South Africa and Tuberculosis

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