Skip to main content
main-content

04.05.2019 | Review Article | Ausgabe 6/2019

European Archives of Oto-Rhino-Laryngology 6/2019

Voice rehabilitation for laryngeal cancer after radiotherapy: a systematic review and meta-analysis

Zeitschrift:
European Archives of Oto-Rhino-Laryngology > Ausgabe 6/2019
Autoren:
Mahoko Taito, Shunsuke Taito, Masahiro Banno, Takashi Fujiwara, Hitoshi Okamura, Hiraku Tsujimoto, Yuki Kataoka, Yasushi Tsujimoto
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s00405-019-05452-2) contains supplementary material, which is available to authorized users.
A comment to this article is available online at https://​doi.​org/​10.​1007/​s00405-019-05586-3.
A comment to this article is available online at https://​doi.​org/​10.​1007/​s00405-019-05596-1.

Publisher's Note

pringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Abstract

Purpose

We aimed to determine whether voice rehabilitation after radiotherapy improves the quality of life (QOL), voice function, and self-rated voice function in patients with laryngeal cancer.

Methods

We searched CENTRAL, MEDLINE, EMBASE, PEDro, and World Health Organization International Clinical Trials Registry Platform for randomized controlled trials published between inception and October 2018. The primary outcome was QOL, adverse events and mortality. Secondary outcomes included voice function and self-rated voice function. The quality of evidence was determined using the Grading of Recommendations Assessment, Development, and Evaluation approach.

Results

Three trials (enrolling 122 patients) compared voice rehabilitation to usual care or no intervention after radiotherapy. Voice rehabilitation did not significantly improve any QOL scores. Data on adverse events and mortality were not available in any of the trials. Voice rehabilitation did not improve any voice function scores, such as jitter (mean difference: – 0.48 [– 1.27 to 0.32]), shimmer (mean difference: – 0.04 [– 0.27 to 0.19]), maximum phonation time (mean difference: 1.54 [– 1.13 to 4.22]), and the grade, roughness, breathiness, asthenia, and strain scale (mean difference: – 0.39 [– 2.59 to 1.80]). Voice rehabilitation also did not improve the voice handicap index, which was used as a self-rated voice function score (mean difference: 5.54 [– 2.07 to 13.16]). The certainty of the evidence was graded as low for primary and secondary outcomes.

Conclusion

Voice rehabilitation for patients with laryngeal cancer after radiotherapy might not improve QOL, voice function, and self-rated voice function. Pre-specified voice rehabilitation programs may not be necessary for all patients with laryngeal cancer after radiotherapy.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Weitere Produktempfehlungen anzeigen
Zusatzmaterial
Supplementary file1 (DOC 64 kb)
405_2019_5452_MOESM1_ESM.doc
Supplementary file2 (DOCX 16 kb)
405_2019_5452_MOESM2_ESM.docx
Supplementary file3 (DOCX 17 kb)
405_2019_5452_MOESM3_ESM.docx
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 6/2019

European Archives of Oto-Rhino-Laryngology 6/2019 Zur Ausgabe
  1. Sie können e.Med HNO 14 Tage kostenlos testen (keine Print-Zeitschrift enthalten). Der Test läuft automatisch und formlos aus. Es kann nur einmal getestet werden.

Neu im Fachgebiet HNO

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update HNO und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise