Skip to main content
main-content

01.02.2014 | Original Research Article | Ausgabe 1/2014

Documenta Ophthalmologica 1/2014

Waveform variance and latency jitter of the visual evoked potential in childhood

Zeitschrift:
Documenta Ophthalmologica > Ausgabe 1/2014
Autoren:
John P. Kelly, Felix Darvas, Avery H. Weiss

Abstract

Purpose

Recording the visual evoked potential (VEP) in young children is challenging due to movement artifacts with variable fixation or attention. This study examined the effects of latency jitter, noise, and waveform consistency on the averaging of the VEP across childhood age.

Methods

Stimuli were contrast-reversing (1.4 Hz) checkerboards of 163 arc minutes and pattern-onset-offset of 0.5 cycle/degree horizontal sine-wave gratings. Subjects were 79 normal children (0.3–16 years age; mean 6.9). Results were compared to recordings of EEG noise only (noise controls). Epochs underwent four averaging methods: (1) latency jitter correction using cross-correlation, (2) correction of phase shifts across a limited bandwidth in the Fourier domain, (3) selection of epochs based on consistency in the time domain, and (4) selection of epochs based on phase consistency in the Fourier domain. Signal-to-noise ratios (SNR) were estimated in both the time and Fourier domains.

Results

Compared to standard averaging, all methods improved the amplitude of the primary peak (P100) while generating mild changes in latency. All methods also increased amplitudes of residual peaks in noise controls. In VEPs with an adequate SNR, selective averaging in the Fourier domain provided the greatest improvement in amplitude (61 % increase; p < 0.0001) without prolongation in latency. Correction of latency jitter did not consistently improve amplitude but caused latency prolongation in 24 % of subjects. There was no age-related effect of any averaging method for either stimulus.

Conclusions

Since latency jitter correction does not improve VEP amplitude more than selective averaging, recording artifacts in children are dominated by random phase components rather than inducing latency jitter.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2014

Documenta Ophthalmologica 1/2014 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

06.08.2019 | Leitthema | Ausgabe 9/2019

Forschungs- und Entwicklungsbedarf in der Augenheilkunde („Unmet needs“)

Ein konsensbasierter Fahrplan des European Vision Institute (EVI) für die Jahre 2019 bis 2025

01.08.2019 | Erkrankungen der Hornhaut | CME | Ausgabe 8/2019

Neurotrophe Keratopathie

Grundlagen, Diagnostik und Therapie

22.07.2019 | DFP-Fortbildung | Ausgabe 4/2019 Open Access

Aktuelle Möglichkeiten der visuellen Rehabilitation