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Erschienen in:
16.04.2021 | Original Article
Well differentiated carcinoma with a poor prognosis: a retrospective analysis of papillary gastric adenocarcinoma
Erschienen in: Surgery Today | Ausgabe 8/2021
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Purpose
To explore the clinicopathological features and prognosis of papillary gastric adenocarcinoma (PGC).
Methods
The subjects of this retrospective analysis were 1525 patients with gastric cancer in a single center in China.
Results
The patients with PGC were generally of advanced age and the tumor was located in the upper 1/3 of the stomach. PGC was well or moderately differentiated, with serosal infiltration, early lymph node metastasis, TNM stages I/II, liver metastasis, and a short postoperative overall survival time. Patients with the secondary pathological type of papillary adenocarcinoma presented with clinicopathological similarities to those with primary PGC. PGC was a risk factor for poor survival in both univariate and multivariate analyses.
Conclusion
Papillary gastric adenocarcinoma (PGC) showed different clinicopathological characteristics and prognosis to other types of gastric cancer (GC), even if it was not the primary pathological type. The higher the proportion of papillary adenocarcinoma in gastric cancer samples, the shorter the postoperative survival time of patients. PGC needs further multicenter studies.