Skip to main content
Erschienen in: MMW - Fortschritte der Medizin 22/2012

20.12.2012 | FORTBILDUNG

Wenn möglich: organerhaltend operieren

Behandlungsoptionen beim Nierenzellkarzinom

verfasst von: Jozefina Casucelli, Prof. Dr. med. Michael Fischereder, Priv.-Doz. Dr. med. Christian Gratzke, Priv.-Doz. Dr. med. Michael Staehler, Prof. Dr. med. Christian G. Stief

Erschienen in: MMW - Fortschritte der Medizin | Ausgabe 22/2012

Einloggen, um Zugang zu erhalten

Zusammenfassung

Die einzig kurative Therapie des Nierenzellkarzinoms ist die Operation. Allerdings werden nach radikaler Nephrektomie häufig erhöhte Retentionswerte als Zeichen einer chronischen Niereninsuffizienz und in der Folge ein erhöhtes Sterberisiko beobachtet. Deshalb sollte – wenn möglich – nur ein Teil der Niere entfernt werden. Dafür stehen verschiedene Methoden zur Verfügung.

Literatur
  1. Agodoa Ly, Appel L, Bakris Gl et al. (2001) Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: a randomized controlled trial. JAMA 285:2719–2728PubMedView Article
  2. Aron M, Kamoi K, Remer E et al. (2010) Laparoscopic renal cryoablation: 8-year, single surgeon outcomes. J Urol 183:889–895PubMedView Article
  3. Benway Bm, Bhayani Sb, Rogers Cg et al. (2009) Robot assisted partial nephrectomy versus laparoscopic partial nephrectomy for renal tumors: a multi-institutional analysis of perioperative outcomes. J Urol. 182:866–872PubMedView Article
  4. Campbell Sc, Novick Ac, Belldegrun A et al. (2009) Guideline for management of the clinical T1 renal mass. J Urol. 182:1271–1279PubMedView Article
  5. Clark Wf, Macnab Jj, Sontrop Jm et al. (2011) Dipstick proteinuria as a screening strategy to identify rapid renal decline. J Am Soc Nephrol. 22:1729–1736PubMedView Article
  6. Frank I, Blute Ml, Cheville Jc et al. (2003) Solid renal tumors: an analysis of pathological features related to tumor size. J Urol. 170:2217–2220PubMedView Article
  7. Gill Is, Kavoussi Lr, Lane Br et al. (2007) Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors. J Urol. 178:41–46PubMedView Article
  8. Go As, Bansal N, Chandra M et al. (2011) Chronic kidney disease and risk for presenting with acute myocardial infarction versus stable exertional angina in adults with coronary heart disease. J Am Coll Cardiol. 58:1600–1607PubMedView Article
  9. Hollingsworth Jm, Miller Dc, Daignault S et al. (2006) Rising incidence of small renal masses: a need to reassess treatment effect. J Natl Cancer Inst. 98:1331–1334PubMedView Article
  10. Huang Wc, Elkin Eb, Levey As et al. (2009) Partial nephrectomy versus radical nephrectomy in patients with small renal tumors—is there a difference in mortality and cardiovascular outcomes?. J Urol. 181:55–61; discussion 61-52PubMedView Article
  11. Huang Wc, Levey As, Serio Am et al. (2006) Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study. Lancet Oncol. 7:735–740PubMedView Article
  12. Klingler Hc, Marberger M, Mauermann J et al. (2007) ’skipping’ is still a problem with radiofrequency ablation of small renal tumours. BJU Int. 99:998–1001PubMedView Article
  13. Kunkle Da, Uzzo Rg (2008) Cryoablation or radiofrequency ablation of the small renal mass: a meta-analysis. Cancer. 113:2671–2680PubMedView Article
  14. Lane Br, Russo P, Uzzo Rg et al. (2011) Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function. J Urol. 185:421–427PubMedView Article
  15. Ljungberg B, Cowan Nc, Hanbury Dc et al. (2010) EAU guidelines on renal cell carcinoma: the 2010 update. Eur Urol. 58:398–406PubMedView Article
  16. Mathew A, Devesa Ss, Fraumeni Jf, Jr. et al. (2002) Global increases in kidney cancer incidence, 1973-1992. Eur J Cancer Prev. 11:171–178PubMedView Article
  17. Mues Ac, Okhunov Z, Haramis G et al. (2010) Comparison of percutaneous and laparoscopic renal cryoablation for small (<3.0 cm) renal masses. J Endourol. 24:1097–1100PubMedView Article
  18. Ponsky Le, Crownover Rl, Rosen Mj et al. (2003) Initial evaluation of Cyberknife technology for extracorporeal renal tissue ablation. Urology. 61:498–501PubMedView Article
  19. Ritchie Rw, Leslie Ta, Turner Gd et al. (2011) Laparoscopic high-intensity focused ultrasound for renal tumours: a proof of concept study. BJU Int. 107:1290–1296PubMedView Article
  20. Santos Arrontes D, Fernandez Acenero Mj, Garcia Gonzalez Ji et al. (2008) Survival analysis of clear cell renal carcinoma according to the Charlson comorbidity index. J Urol. 179:857–861PubMedView Article
  21. Stief Cg (2011) If a partial nephrectomy could be done safely for a renal tumor, would radical nephrectomy be considered malpractice?. Eur Urol. 60:465–466; discussion 466-467PubMedView Article
  22. Thompson Rh, Lane Br, Lohse Cm et al. (2010) Every minute counts when the renal hilum is clamped during partial nephrectomy. Eur Urol. 58:340–345PubMedView Article
  23. Van Poppel H, Da Pozzo L, Albrecht W et al. (2011) A prospective, randomised EORTC intergroup phase 3 study comparing the oncologic outcome of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma. Eur Urol. 59:543–552PubMedView Article
  24. Van Poppel H, Da Pozzo L, Albrecht W et al. (2007) A prospective randomized EORTC intergroup phase 3 study comparing the complications of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma. Eur Urol. 51:1606–1615PubMedView Article
  25. Volpe A, Jewett Ma (2007) The role of surveillance for small renal masses. Nat Clin Pract Urol. 4:2–3PubMedView Article
  26. Weight Cj, Larson Bt, Fergany Af et al. (2010) Nephrectomy induced chronic renal insufficiency is associated with increased risk of cardiovascular death and death from any cause in patients with localized cT1b renal masses. J Urol. 183:1317–1323PubMedView Article
  27. Zagoria Rj, Pettus Ja, Rogers M et al. (2011) Long-term outcomes after percutaneous radiofrequency ablation for renal cell carcinoma. Urology. 77:1393–1397PubMedView Article
Metadaten
Titel
Wenn möglich: organerhaltend operieren
Behandlungsoptionen beim Nierenzellkarzinom
verfasst von
Jozefina Casucelli
Prof. Dr. med. Michael Fischereder
Priv.-Doz. Dr. med. Christian Gratzke
Priv.-Doz. Dr. med. Michael Staehler
Prof. Dr. med. Christian G. Stief
Publikationsdatum
20.12.2012
Verlag
Urban and Vogel
Erschienen in
MMW - Fortschritte der Medizin / Ausgabe 22/2012
Print ISSN: 1438-3276
Elektronische ISSN: 1613-3560
DOI
https://doi.org/10.1007/s15006-012-1689-4

Weitere Artikel der Ausgabe 22/2012

MMW - Fortschritte der Medizin 22/2012 Zur Ausgabe

AKTUELLE MEDIZIN

Tierisch gute Mediziner

Leitlinien kompakt für die Allgemeinmedizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Facharzt-Training Allgemeinmedizin

Die ideale Vorbereitung zur anstehenden Prüfung mit den ersten 24 von 100 klinischen Fallbeispielen verschiedener Themenfelder

Mehr erfahren

Update Allgemeinmedizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.