Erschienen in:
25.05.2018 | Male Sexual Dysfunction and Disorders (AW Pastuszak and NK Gupta, Section Editors)
What Is the Future of Erectile Dysfunction Therapy?
verfasst von:
Jeffrey D. Campbell, Uros Milenkovic, Maarten Albersen, Trinity J. Bivalacqua
Erschienen in:
Current Sexual Health Reports
|
Ausgabe 3/2018
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Abstract
Purpose of Review
Erectile dysfunction (ED) is a burden for the majority of men during their lifetime. Phosphodiesterase type-5 inhibitors are first-line treatment for men with ED; however, they are limited by on-demand dosing, short-term benefits, and reduced efficacy in difficult to treat populations such as men with diabetes mellitus or ED after radical prostatectomy.
Recent Findings
Novel treatment options that offer a durable, tissue restorative approaches are being explored and potentially offer a long-term solution to this medical affliction. Medical therapies such as nanoparticles and botulinum neurotoxin, new technology including vibratory devices and low-intensity extracorporeal shockwave treatment, and regenerative medicine approaches that are undergoing human clinical trials.
Summary
Although preclinical data surrounding novel ED therapies are intriguing, these studies are not yet robust enough to support these endeavors outside of clinical trials and further work is ongoing.