Skip to main content
Erschienen in: Techniques in Coloproctology 8/2015

01.08.2015 | Original Article

When is the best time for temporary stoma closure in laparoscopic sphincter-saving surgery for rectal cancer? A study of 259 consecutive patients

verfasst von: M. N. Figueiredo, D. Mège, L. Maggiori, M. Ferron, Y. Panis

Erschienen in: Techniques in Coloproctology | Ausgabe 8/2015

Einloggen, um Zugang zu erhalten

Abstract

Background

There is no consensus regarding the best timing for temporary stoma closure after proctectomy for rectal cancer, especially if the patient requires adjuvant chemotherapy. This study aimed to assess whether the timing of stoma closure could influence postoperative morbidity.

Methods

Patients with rectal cancer undergoing laparoscopic proctectomy with temporary stoma were included and divided into three groups according to the delay of stoma closure after proctectomy: ≤60 days (Group A), 61–90 days (Group B), and >90 days (Group C).

Results

From 2008 to 2013, 259 patients (146 men, median age 61 years) were divided into Groups A (n = 65), B (n = 115), and C (n = 79). At the time of stoma closure, seven (11 %) patients received adjuvant chemotherapy in Group A versus 42 (37 %) in Group B (p = 0.0002) and 24 (30 %) in Group C (p = 0.004), and peristomal hernia was noted in four patients (6 %) in Group A versus 14 (12 %) in Group B and 21 (27 %) in Group C (p < 0.0001). Although overall postoperative morbidity was similar between groups, anastomotic leakage (at the stoma closure site) was noted in one patient in Group A versus zero in Group B versus four in Group C (p = 0.03). Median hospital stay was 5 days in Group A versus 6 in Group B versus 6 in Group C (p = 0.004).

Conclusions

Our results suggested that timing of temporary stoma closure can influence postoperative morbidity. Best results were obtained if stoma closure was performed before 90 days, even during adjuvant chemotherapy. There is no benefit in delaying stoma closure after completion of adjuvant chemotherapy.
Literatur
1.
Zurück zum Zitat Rullier E, Laurent C, Garrelon JL, Michel P, Saric J, Parneix M (1998) Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 85:355–358CrossRefPubMed Rullier E, Laurent C, Garrelon JL, Michel P, Saric J, Parneix M (1998) Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 85:355–358CrossRefPubMed
2.
Zurück zum Zitat Matthiessen P, Hallböök O, Rutegård J, Simert G, Sjödahl R (2007) Defunctioning stoma reduces symptomatic anastomotic leakage after low anterior resection of the rectum for cancer: a randomized multicenter trial. Ann Surg 246:207–214PubMedCentralCrossRefPubMed Matthiessen P, Hallböök O, Rutegård J, Simert G, Sjödahl R (2007) Defunctioning stoma reduces symptomatic anastomotic leakage after low anterior resection of the rectum for cancer: a randomized multicenter trial. Ann Surg 246:207–214PubMedCentralCrossRefPubMed
3.
Zurück zum Zitat Hüser N, Michalski CW, Erkan M et al (2008) Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery. Ann Surg 248:52–60CrossRefPubMed Hüser N, Michalski CW, Erkan M et al (2008) Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery. Ann Surg 248:52–60CrossRefPubMed
4.
Zurück zum Zitat Tan WS, Tang CL, Shi L, Eu KW (2009) Meta-analysis of defunctioning stomas in low anterior resection for rectal cancer. Br J Surg 96:462–472CrossRefPubMed Tan WS, Tang CL, Shi L, Eu KW (2009) Meta-analysis of defunctioning stomas in low anterior resection for rectal cancer. Br J Surg 96:462–472CrossRefPubMed
5.
Zurück zum Zitat Alves A, Panis Y, Lelong B, Dousset B, Benoist S, Vicaut E (2008) Randomized clinical trial of early versus delayed temporary stoma closure after proctectomy. Br J Surg 95:693–698CrossRefPubMed Alves A, Panis Y, Lelong B, Dousset B, Benoist S, Vicaut E (2008) Randomized clinical trial of early versus delayed temporary stoma closure after proctectomy. Br J Surg 95:693–698CrossRefPubMed
6.
Zurück zum Zitat Shabbir J, Britton DC (2010) Stoma complications: a literature overview. Colorectal Dis 12:958–964CrossRefPubMed Shabbir J, Britton DC (2010) Stoma complications: a literature overview. Colorectal Dis 12:958–964CrossRefPubMed
7.
Zurück zum Zitat Biagi JJ, Raphael MJ, Mackillop WJ, Kong W, King WD, Booth CM (2011) Association between time to initiation of adjuvant chemotherapy and survival in colorectal cancer: a systematic review and meta-analysis. JAMA 305:2335–2342CrossRefPubMed Biagi JJ, Raphael MJ, Mackillop WJ, Kong W, King WD, Booth CM (2011) Association between time to initiation of adjuvant chemotherapy and survival in colorectal cancer: a systematic review and meta-analysis. JAMA 305:2335–2342CrossRefPubMed
8.
Zurück zum Zitat Reid K, Pockney P, Pollitt T, Draganic B, Smith SR (2010) Randomized clinical trial of short-term outcomes following purse-string versus conventional closure of ileostomy wounds. Br J Surg 97:1511–1517CrossRefPubMed Reid K, Pockney P, Pollitt T, Draganic B, Smith SR (2010) Randomized clinical trial of short-term outcomes following purse-string versus conventional closure of ileostomy wounds. Br J Surg 97:1511–1517CrossRefPubMed
9.
Zurück zum Zitat Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213PubMedCentralCrossRefPubMed Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213PubMedCentralCrossRefPubMed
10.
Zurück zum Zitat Montedori A, Cirocchi R, Farinella E, Sciannameo F, Abraha I (2010) Covering ileo- or colostomy in anterior resection for rectal carcinoma. Cochrane Database Syst Rev 12:CD006878 Montedori A, Cirocchi R, Farinella E, Sciannameo F, Abraha I (2010) Covering ileo- or colostomy in anterior resection for rectal carcinoma. Cochrane Database Syst Rev 12:CD006878
11.
Zurück zum Zitat Perez RO, Habr-Gama A, Seid VE et al (2006) Loop ileostomy morbidity: timing of closure matters. Dis Colon Rectum 49:1539–1545CrossRefPubMed Perez RO, Habr-Gama A, Seid VE et al (2006) Loop ileostomy morbidity: timing of closure matters. Dis Colon Rectum 49:1539–1545CrossRefPubMed
12.
Zurück zum Zitat Robertson I, Leung E, Hughes D et al (2005) Prospective analysis of stoma-related complications. Colorectal Dis 7:279–285CrossRefPubMed Robertson I, Leung E, Hughes D et al (2005) Prospective analysis of stoma-related complications. Colorectal Dis 7:279–285CrossRefPubMed
13.
Zurück zum Zitat Jordi-Galais P, Turrin N, Tresallet C, Nguyen-Thanh Q, Chigot JP, Menegaux F (2003) Early closure of temporary stoma of the small bowel. Gastroenterol Clin Biol 27:697–699PubMed Jordi-Galais P, Turrin N, Tresallet C, Nguyen-Thanh Q, Chigot JP, Menegaux F (2003) Early closure of temporary stoma of the small bowel. Gastroenterol Clin Biol 27:697–699PubMed
14.
Zurück zum Zitat Omundsen M, Hayes J, Collinson R, Merrie A, Parry B, Bissett I (2012) Early ileostomy closure: is there a downside? Anz J Surg 82:352–354CrossRefPubMed Omundsen M, Hayes J, Collinson R, Merrie A, Parry B, Bissett I (2012) Early ileostomy closure: is there a downside? Anz J Surg 82:352–354CrossRefPubMed
15.
Zurück zum Zitat Perdawid SK, Andersen OB (2011) Acceptable results of early closure of loop ileostomy to protect low rectal anastomosis. Dan Med Bull 58:a4280PubMed Perdawid SK, Andersen OB (2011) Acceptable results of early closure of loop ileostomy to protect low rectal anastomosis. Dan Med Bull 58:a4280PubMed
16.
Zurück zum Zitat Bakx R, Busch O, Van Geldere D, Bemelman WA, Slors JFM, Van Lanschot JJB (2003) Feasibility of early closure of loop ileostomies: a pilot study. Dis Colon Rectum 46:1680–1684CrossRefPubMed Bakx R, Busch O, Van Geldere D, Bemelman WA, Slors JFM, Van Lanschot JJB (2003) Feasibility of early closure of loop ileostomies: a pilot study. Dis Colon Rectum 46:1680–1684CrossRefPubMed
17.
Zurück zum Zitat Wong KS, Remzi FH, Gorgun E et al (2005) Loop ileostomy closure after restorative proctocolectomy: outcome in 1504 patients. Dis Colon Rectum 48:243–250CrossRefPubMed Wong KS, Remzi FH, Gorgun E et al (2005) Loop ileostomy closure after restorative proctocolectomy: outcome in 1504 patients. Dis Colon Rectum 48:243–250CrossRefPubMed
18.
Zurück zum Zitat Cipe G, Erkek B, Kuzu A, Gecim E (2012) Morbidity and mortality after the closure of a protective loop ileostomy: analysis of possible predictors. Hepatogastroenterology 59:2168–2172PubMed Cipe G, Erkek B, Kuzu A, Gecim E (2012) Morbidity and mortality after the closure of a protective loop ileostomy: analysis of possible predictors. Hepatogastroenterology 59:2168–2172PubMed
19.
Zurück zum Zitat Tulchinsky H, Shacham-shmueli E, Klausner JM, Inbar M, Geva R (2014) Should a loop ileostomy closure in rectal cancer patients be done during or after adjuvant chemotherapy? J Surg Oncol 109:266–269CrossRefPubMed Tulchinsky H, Shacham-shmueli E, Klausner JM, Inbar M, Geva R (2014) Should a loop ileostomy closure in rectal cancer patients be done during or after adjuvant chemotherapy? J Surg Oncol 109:266–269CrossRefPubMed
Metadaten
Titel
When is the best time for temporary stoma closure in laparoscopic sphincter-saving surgery for rectal cancer? A study of 259 consecutive patients
verfasst von
M. N. Figueiredo
D. Mège
L. Maggiori
M. Ferron
Y. Panis
Publikationsdatum
01.08.2015
Verlag
Springer Milan
Erschienen in
Techniques in Coloproctology / Ausgabe 8/2015
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-015-1328-z

Weitere Artikel der Ausgabe 8/2015

Techniques in Coloproctology 8/2015 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.