Skip to main content
Erschienen in: Social Psychiatry and Psychiatric Epidemiology 11/2018

29.06.2018 | Original Paper

Which mental disorders are associated with the greatest impairment in functioning?

verfasst von: Mark J. Edlund, Jiantong Wang, Kristen Gulledge Brown, Valerie L. Forman-Hoffman, Sara L. Calvin, Sarra L. Hedden, Jonaki Bose

Erschienen in: Social Psychiatry and Psychiatric Epidemiology | Ausgabe 11/2018

Einloggen, um Zugang zu erhalten

Abstract

Objective

The objective of this study is to estimate the comparative associations of mental disorders with three measures of functional impairment: the Global Assessment of Functioning (GAF); the number of days in the past 12 months of total inability to work or carry out normal activities because of emotions, nerves, or mental health (i.e., days out of role); and a modified version of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0).

Methods

Secondary data analysis of the linked Mental Health Surveillance Study and the National Survey on Drug Use and Health (n = 5653), nationally representative population surveys conducted in the United States. Generalized linear models assessed the independent effects of mental disorders on each measure of functional impairment, controlling for mental disorder comorbidity, physical health disorders, and sociodemographic factors.

Results

The results varied across measures of functional impairment. However, mood disorders generally tended to be associated with the greatest functional impairment, anxiety disorders with intermediate impairment, and substance use disorders with the least impairment. All 15 disorders were significantly associated with the GAF score in multiple regression models, eight disorders were significantly associated with the WHODAS score, and three disorders were significantly associated with days out of role.

Conclusions

Our results highlight the value of complementary measures of functional impairment.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Ustun TB, Kostanjsek S, Chatterji S, Rehm J (eds) (2010) Measuring health and disability: manual for WHO disability assessment schedule (WHODAS 2.0). World Health Organization, Geneva Ustun TB, Kostanjsek S, Chatterji S, Rehm J (eds) (2010) Measuring health and disability: manual for WHO disability assessment schedule (WHODAS 2.0). World Health Organization, Geneva
2.
Zurück zum Zitat Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJL (2006) Global burden of disease and risk factors. Oxford University Press and the World Bank, Washington, DCCrossRef Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJL (2006) Global burden of disease and risk factors. Oxford University Press and the World Bank, Washington, DCCrossRef
3.
Zurück zum Zitat Stouthard MEA, Essink-Bot ML, Bonsel GJ, Barendregt JJM, Kramers PGN, van de Water HPA, Gunning-Schepers LJ, van der Maas PJ (1997) Disability weights for diseases in the Netherlands. Erasmus University Rotterdam, Rotterdam Stouthard MEA, Essink-Bot ML, Bonsel GJ, Barendregt JJM, Kramers PGN, van de Water HPA, Gunning-Schepers LJ, van der Maas PJ (1997) Disability weights for diseases in the Netherlands. Erasmus University Rotterdam, Rotterdam
7.
Zurück zum Zitat Alonso J, Petukhova M, Vilagut G, Chatterji S, Heeringa S, Ustun TB, Alhamzawi AO, Viana MC, Angermeyer M, Bromet E, Bruffaerts R, de Girolamo G, Florescu S, Gureje O, Haro JM, Hinkov H, Hu CY, Karam EG, Kovess V, Levinson D, Medina-Mora ME, Nakamura Y, Ormel J, Posada-Villa J, Sagar R, Scott KM, Tsang A, Williams DR, Kessler RC (2011) Days out of role due to common physical and mental conditions: results from the WHO world mental health surveys. Mol Psychiatry 16(12):1234–1246. https://doi.org/10.1038/mp.2010.101 CrossRef Alonso J, Petukhova M, Vilagut G, Chatterji S, Heeringa S, Ustun TB, Alhamzawi AO, Viana MC, Angermeyer M, Bromet E, Bruffaerts R, de Girolamo G, Florescu S, Gureje O, Haro JM, Hinkov H, Hu CY, Karam EG, Kovess V, Levinson D, Medina-Mora ME, Nakamura Y, Ormel J, Posada-Villa J, Sagar R, Scott KM, Tsang A, Williams DR, Kessler RC (2011) Days out of role due to common physical and mental conditions: results from the WHO world mental health surveys. Mol Psychiatry 16(12):1234–1246. https://​doi.​org/​10.​1038/​mp.​2010.​101 CrossRef
11.
Zurück zum Zitat Scott KM, Von Korff M, Alonso J, Angermeyer MC, Fayyad J, de Girolamo G, Demyttenaere K, Gasquet I, Gureje O, Haro JM, He Y, Kessler RC, Levinson D, Medina Mora ME, Oakley Browne M, Ormel J, Posada-Villa J, Watanabe M, Williams D (2009) Mental-physical co-morbidity and its relationship with disability: results from the World Mental Health Survey. Psychol Med 39:33–43CrossRef Scott KM, Von Korff M, Alonso J, Angermeyer MC, Fayyad J, de Girolamo G, Demyttenaere K, Gasquet I, Gureje O, Haro JM, He Y, Kessler RC, Levinson D, Medina Mora ME, Oakley Browne M, Ormel J, Posada-Villa J, Watanabe M, Williams D (2009) Mental-physical co-morbidity and its relationship with disability: results from the World Mental Health Survey. Psychol Med 39:33–43CrossRef
12.
Zurück zum Zitat Andrade LH, Baptista MC, Alonso J, Petukhova M, Bruffaerts R, Kessler RC, Silveira CM, Siu ER, Wang YP, Viana MC (2013) Days out-of-role due to common physical and mental health problems: results from the Sao Paulo Megacity Mental Health Survey, Brazil. Clinics (Sao Paulo) 68:1392–1399CrossRef Andrade LH, Baptista MC, Alonso J, Petukhova M, Bruffaerts R, Kessler RC, Silveira CM, Siu ER, Wang YP, Viana MC (2013) Days out-of-role due to common physical and mental health problems: results from the Sao Paulo Megacity Mental Health Survey, Brazil. Clinics (Sao Paulo) 68:1392–1399CrossRef
16.
Zurück zum Zitat Kessler RC, Ustun TB (2004) The World Mental Health (WMH) survey initiative version of the World Health Organization (WHO) composite international diagnostic interview (CIDI). Int J Methods Psychiatr Res 13(2):93–121CrossRef Kessler RC, Ustun TB (2004) The World Mental Health (WMH) survey initiative version of the World Health Organization (WHO) composite international diagnostic interview (CIDI). Int J Methods Psychiatr Res 13(2):93–121CrossRef
17.
Zurück zum Zitat First MB, Spitzer RL, Gibbon M, Williams JBW (2002) Structured clinical interview for DSM-IV-TR Axis I disorders, research version, patient edition. SCID-I/P) Biometrics Research, New York State Psychiatric Institute, New York First MB, Spitzer RL, Gibbon M, Williams JBW (2002) Structured clinical interview for DSM-IV-TR Axis I disorders, research version, patient edition. SCID-I/P) Biometrics Research, New York State Psychiatric Institute, New York
18.
Zurück zum Zitat Jackson JS, Torres M, Caldwell CH, Neighbors HW, Nesse RM, Taylor RJ, Trierweiler SJ, Williams DR (2004) The National Survey of American Life: a study of racial, ethnic and cultural influences on mental disorders and mental health. Int J Methods Psychiatr Res 13(4):196–207CrossRef Jackson JS, Torres M, Caldwell CH, Neighbors HW, Nesse RM, Taylor RJ, Trierweiler SJ, Williams DR (2004) The National Survey of American Life: a study of racial, ethnic and cultural influences on mental disorders and mental health. Int J Methods Psychiatr Res 13(4):196–207CrossRef
19.
Zurück zum Zitat Haro JM, Arbabzadeh-Bouchez S, Brugha TS, de Girolamo G, Guyer ME, Jin R, Lepine JP, Mazzi F, Reneses B, Vilagut G, Sampson NA, Kessler RC (2006) Concordance of the composite international diagnostic interview version 3.0 (CIDI 3.0) with standardized clinical assessments in the WHO World Mental Health surveys. Int J Methods Psychiatr Res 15(4):167–180CrossRef Haro JM, Arbabzadeh-Bouchez S, Brugha TS, de Girolamo G, Guyer ME, Jin R, Lepine JP, Mazzi F, Reneses B, Vilagut G, Sampson NA, Kessler RC (2006) Concordance of the composite international diagnostic interview version 3.0 (CIDI 3.0) with standardized clinical assessments in the WHO World Mental Health surveys. Int J Methods Psychiatr Res 15(4):167–180CrossRef
20.
Zurück zum Zitat Kessler RC, Santiago PN, Colpe LJ, Dempsey CL, First MB, Heeringa SG, Stein MB, Fullerton CS, Gruber MJ, Naifeh JA, Nock MK, Sampson NA, Schoenbaum M, Zaslavsky AM, Ursano RJ (2013) Clinical reappraisal of the Composite International Diagnostic Interview screening scales (CIDI-SC) in the army study to assess risk and resilience in servicemembers (Army STARRS). Int J Methods Psychiatr Res 22(4):303–321. https://doi.org/10.1002/mpr.1398 CrossRefPubMedPubMedCentral Kessler RC, Santiago PN, Colpe LJ, Dempsey CL, First MB, Heeringa SG, Stein MB, Fullerton CS, Gruber MJ, Naifeh JA, Nock MK, Sampson NA, Schoenbaum M, Zaslavsky AM, Ursano RJ (2013) Clinical reappraisal of the Composite International Diagnostic Interview screening scales (CIDI-SC) in the army study to assess risk and resilience in servicemembers (Army STARRS). Int J Methods Psychiatr Res 22(4):303–321. https://​doi.​org/​10.​1002/​mpr.​1398 CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Segal DL, Kabacoff RI, Hersen M, Van Hasselt VB, Ryan C (1995) Update on the reliability of diagnosis in older psychiatric outpatients using the structured clinical interview of DSM III-R. J Clin Geropsychol 1(4):313–321 Segal DL, Kabacoff RI, Hersen M, Van Hasselt VB, Ryan C (1995) Update on the reliability of diagnosis in older psychiatric outpatients using the structured clinical interview of DSM III-R. J Clin Geropsychol 1(4):313–321
23.
Zurück zum Zitat Zanarini MC, Skodol AE, Bender D, Dolan R, Sanislow C, Schaefer E, Morey LC, Grilo CM, Shea MT, McGlashan TH, Gunderson JG (2000) The collaborative longitudinal personality disorders study: reliability of axis I and II diagnoses. J Pers Disord 14(4):291–299CrossRef Zanarini MC, Skodol AE, Bender D, Dolan R, Sanislow C, Schaefer E, Morey LC, Grilo CM, Shea MT, McGlashan TH, Gunderson JG (2000) The collaborative longitudinal personality disorders study: reliability of axis I and II diagnoses. J Pers Disord 14(4):291–299CrossRef
24.
Zurück zum Zitat Fennig S, Craig T, Lavelle J, Kovasznay B, Bromet EJ (1994) Best-estimate versus structured interview-based diagnosis in first-admission psychosis. Compr Psychiatry 35(5):341–348CrossRef Fennig S, Craig T, Lavelle J, Kovasznay B, Bromet EJ (1994) Best-estimate versus structured interview-based diagnosis in first-admission psychosis. Compr Psychiatry 35(5):341–348CrossRef
25.
Zurück zum Zitat Kranzler HR, Kadden RM, Babor TF, Tennen H, Rounsaville BJ (1996) Validity of the SCID in substance abuse patients. Addiction 91(6):859–868CrossRef Kranzler HR, Kadden RM, Babor TF, Tennen H, Rounsaville BJ (1996) Validity of the SCID in substance abuse patients. Addiction 91(6):859–868CrossRef
26.
Zurück zum Zitat Kranzler HR, Kadden RM, Burleson JA, Babor TF, Apter A, Rounsaville BJ (1995) Validity of psychiatric diagnoses in patients with substance use disorders: Is the interview more important than the interviewer? Compr Psychiatry 36:278–288CrossRef Kranzler HR, Kadden RM, Burleson JA, Babor TF, Apter A, Rounsaville BJ (1995) Validity of psychiatric diagnoses in patients with substance use disorders: Is the interview more important than the interviewer? Compr Psychiatry 36:278–288CrossRef
29.
Zurück zum Zitat Steiner JL, Tebes JK, Sledge WH, Walker ML (1995) A comparison of the structured clinical interview for DSM-III-R and clinical diagnoses. J Nerv Ment Dis 183(6):365–369CrossRef Steiner JL, Tebes JK, Sledge WH, Walker ML (1995) A comparison of the structured clinical interview for DSM-III-R and clinical diagnoses. J Nerv Ment Dis 183(6):365–369CrossRef
31.
32.
Zurück zum Zitat Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ (1992) A population-based twin study of major depression in women. The impact of varying definitions of illness. Arch Gen Psychiatry 49(4):257–266CrossRef Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ (1992) A population-based twin study of major depression in women. The impact of varying definitions of illness. Arch Gen Psychiatry 49(4):257–266CrossRef
33.
Zurück zum Zitat Kessler RC, Abelson J, Demler O, Escobar JI, Gibbon M, Guyer ME, Howes MJ, Jin R, Vega WA, Walters EE, Wang P, Zaslavsky A, Zheng H (2004) Clinical calibration of DSM-IV diagnoses in the World Mental Health (WMH) version of the World Health Organization (WHO) Composite International Diagnostic Interview (WMH-CIDI). Int J Methods Psychiatr Res 13(2):122–139. https://doi.org/10.1002/mpr.169 CrossRef Kessler RC, Abelson J, Demler O, Escobar JI, Gibbon M, Guyer ME, Howes MJ, Jin R, Vega WA, Walters EE, Wang P, Zaslavsky A, Zheng H (2004) Clinical calibration of DSM-IV diagnoses in the World Mental Health (WMH) version of the World Health Organization (WHO) Composite International Diagnostic Interview (WMH-CIDI). Int J Methods Psychiatr Res 13(2):122–139. https://​doi.​org/​10.​1002/​mpr.​169 CrossRef
36.
Zurück zum Zitat Sobin C, Weissman MM, Goldstein RB, Adams P, Wickramaratne P, Warner V, Lish JD (1993) Diagnostic interviewing for family studies: comparing telephone and face-to-face methods for the diagnosis of lifetime psychiatric disorders. Psychiatr Genet 3:227–233CrossRef Sobin C, Weissman MM, Goldstein RB, Adams P, Wickramaratne P, Warner V, Lish JD (1993) Diagnostic interviewing for family studies: comparing telephone and face-to-face methods for the diagnosis of lifetime psychiatric disorders. Psychiatr Genet 3:227–233CrossRef
37.
Zurück zum Zitat American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders. Text revision (DSM-IV-TR), 4th edn. American Psychiatric Association, Washington, DC American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders. Text revision (DSM-IV-TR), 4th edn. American Psychiatric Association, Washington, DC
39.
Zurück zum Zitat Center for Behavioral Health Statistics and Quality (CBHSQ) (2014) Sample weighting. In: 2012 national survey on drug use and health: methodological resource book (section 16a, 2012 mental health surveillanc study: design and estimation report). Substance Abuse and Mental Health Services Administration, Rockville Center for Behavioral Health Statistics and Quality (CBHSQ) (2014) Sample weighting. In: 2012 national survey on drug use and health: methodological resource book (section 16a, 2012 mental health surveillanc study: design and estimation report). Substance Abuse and Mental Health Services Administration, Rockville
40.
Zurück zum Zitat American Psychiatric Association (1987) Diagnostic and statistical manual of mental disorders (3rd edition, revised) (DSM-III-R). American Psychiatric Association, Washington, DC American Psychiatric Association (1987) Diagnostic and statistical manual of mental disorders (3rd edition, revised) (DSM-III-R). American Psychiatric Association, Washington, DC
41.
Zurück zum Zitat American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders fifth edition (DSM-5). American Psychiatric Association, Washington, DCCrossRef American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders fifth edition (DSM-5). American Psychiatric Association, Washington, DCCrossRef
42.
Zurück zum Zitat Gold LH (2014) DSM-5 and the assessment of functioning: the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). J Am Acad Psychiatry Law 42(2):173–181PubMed Gold LH (2014) DSM-5 and the assessment of functioning: the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0). J Am Acad Psychiatry Law 42(2):173–181PubMed
43.
Zurück zum Zitat Veterans Health Administration (2016) Intensive community mental health recovery services VHA Handbook 1163.06. Department of Veterans Affairs, Washington, DC Veterans Health Administration (2016) Intensive community mental health recovery services VHA Handbook 1163.06. Department of Veterans Affairs, Washington, DC
Metadaten
Titel
Which mental disorders are associated with the greatest impairment in functioning?
verfasst von
Mark J. Edlund
Jiantong Wang
Kristen Gulledge Brown
Valerie L. Forman-Hoffman
Sara L. Calvin
Sarra L. Hedden
Jonaki Bose
Publikationsdatum
29.06.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Social Psychiatry and Psychiatric Epidemiology / Ausgabe 11/2018
Print ISSN: 0933-7954
Elektronische ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-018-1554-6

Weitere Artikel der Ausgabe 11/2018

Social Psychiatry and Psychiatric Epidemiology 11/2018 Zur Ausgabe

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.