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25.10.2018 | Editorial

Which patients with acute stroke due to proximal occlusion should not be treated with endovascular thrombectomy?

verfasst von: Mayank Goyal, Mohammed A. Almekhlafi, Christoph Cognard, Ryan McTaggart, Kristine Blackham, Alessandra Biondi, Aad van der Lugt, Charles B. L. M. Majoie, Wim H. van Zwam, H. Bart van der Worp, Michael D. Hill

Erschienen in: Neuroradiology | Ausgabe 1/2019

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Excerpt

Endovascular thrombectomy for acute anterior circulation large vessel proximal occlusion is the standard of care [1]. Evidence from recent trials and additional meta-analyses show that thrombectomy has broad efficacy in almost all sub-groups. Overall, thrombectomy is effective irrespective of age, sex, or the stroke severity at presentation. DAWN [2], DEFUSE3 [3], and late window patients in ESCAPE [4] trials show the benefit of thrombectomy up to 24 h. Data from HERMES collaboration show benefit with thrombectomy even in patients with large ischemic core [(irrespective of whether evaluated on the Alberta Stroke Program Early CT Score (ASPECTS) or CT perfusion (CTP)] and moderate to good collaterals [5, 6]. While there remains no published data from randomized trials on more distal occlusions, evidence from quality registries on thrombectomy in sizable middle cerebral artery M2-segment occlusions suggests that thrombectomy is safe and effective [7‐11]. The further incentive can be found in the dismal natural history of acute proximal occlusion and the low complication rate of thrombectomy, in trials and registries [1]. Based on data from randomized controlled trials, the procedure is cost-effective [12‐14]. …

Goyal M, Menon BK, van Zwam WH, Dippel DW, Mitchell PJ, Demchuk AM, Davalos A, Majoie CB, van der Lugt A, de Miquel MA, Donnan GA, Roos YB, Bonafe A, Jahan R, Diener HC, van den Berg LA, Levy EI, Berkhemer OA, Pereira VM, Rempel J, Millan M, Davis SM, Roy D, Thornton J, Roman LS, Ribo M, Beumer D, Stouch B, Brown S, Campbell BC, van Oostenbrugge RJ, Saver JL, Hill MD, Jovin TG, collaborators H (2016) Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 387(10029):1723–1731. https://doi.org/10.1016/S0140-6736(16)00163-X CrossRefPubMed

Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, Sila CA, Hassan AE, Millan M, Levy EI, Mitchell P, Chen M, English JD, Shah QA, Silver FL, Pereira VM, Mehta BP, Baxter BW, Abraham MG, Cardona P, Veznedaroglu E, Hellinger FR, Feng L, Kirmani JF, Lopes DK, Jankowitz BT, Frankel MR, Costalat V, Vora NA, Yoo AJ, Malik AM, Furlan AJ, Rubiera M, Aghaebrahim A, Olivot JM, Tekle WG, Shields R, Graves T, Lewis RJ, Smith WS, Liebeskind DS, Saver JL, Jovin TG, Investigators DT (2017) Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med 378:11–21. https://doi.org/10.1056/NEJMoa1706442 CrossRefPubMed

Albers GW, Marks MP, Kemp S, Christensen S, Tsai JP, Ortega-Gutierrez S, McTaggart RA, Torbey MT, Kim-Tenser M, Leslie-Mazwi T, Sarraj A, Kasner SE, Ansari SA, Yeatts SD, Hamilton S, Mlynash M, Heit JJ, Zaharchuk G, Kim S, Carrozzella J, Palesch YY, Demchuk AM, Bammer R, Lavori PW, Broderick JP, Lansberg MG (2018) Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging. N Engl J Med 378(8):708–718. https://doi.org/10.1056/NEJMoa1713973 CrossRefPubMedPubMedCentral

Goyal M, Demchuk AM, Menon BK, Eesa M, Rempel JL, Thornton J, Roy D, Jovin TG, Willinsky RA, Sapkota BL, Dowlatshahi D, Frei DF, Kamal NR, Montanera WJ, Poppe AY, Ryckborst KJ, Silver FL, Shuaib A, Tampieri D, Williams D, Bang OY, Baxter BW, Burns PA, Choe H, Heo JH, Holmstedt CA, Jankowitz B, Kelly M, Linares G, Mandzia JL, Shankar J, Sohn SI, Swartz RH, Barber PA, Coutts SB, Smith EE, Morrish WF, Weill A, Subramaniam S, Mitha AP, Wong JH, Lowerison MW, Sajobi TT, Hill MD (2015) Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 372(11):1019–1030. https://doi.org/10.1056/NEJMoa1414905 CrossRefPubMed

San Román L, Menon BK, Blasco J, Hernández-Pérez M, Dávalos A, Majoie CB, Campbell BC, Guillemin F, Lingsma H, Anxionnat R (2018) Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data. Lancet Neurol 17(10):895–904CrossRefPubMed

Goyal M, Menon BK, van Zwam WH, Dippel DW, Mitchell PJ, Demchuk AM, Davalos A, Majoie CB, van der Lugt A, de Miquel MA, Donnan GA, Roos YB, Bonafe A, Jahan R, Diener HC, van den Berg LA, Levy EI, Berkhemer OA, Pereira VM, Rempel J, Millan M, Davis SM, Roy D, Thornton J, Roman LS, Ribo M, Beumer D, Stouch B, Brown S, Campbell BC, van Oostenbrugge RJ, Saver JL, Hill MD, Jovin TG (2016) Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 387 (10029):1723–1731. https://doi.org/10.1016/S0140-6736(16)00163-XS0140-6736(16)00163-X [pii]

Sarraj A, Sangha N, Hussain MS, Wisco D, Vora N, Elijovich L, Goyal N, Abraham M, Mittal M, Feng L, Wu A, Janardhan V, Nalluri S, Yoo AJ, George M, Edgell R, Shah RJ, Sitton C, Supsupin E, Bajgur S, Denny MC, Chen PR, Dannenbaum M, Martin-Schild S, Savitz SI, Gupta R (2016) Endovascular therapy for acute ischemic stroke with occlusion of the middle cerebral artery M2 segment. Jama Neurol 73(11):1291–1296. https://doi.org/10.1001/jamaneurol.2016.27732548269 [pii]

Coutinho JM, Liebeskind DS, Slater LA, Nogueira RG, Baxter BW, Levy EI, Siddiqui AH, Goyal M, Zaidat OO, Davalos A, Bonafe A, Jahan R, Gralla J, Saver JL, Pereira VM (2016) Mechanical thrombectomy for isolated M2 occlusions: a post hoc analysis of the STAR, SWIFT, and SWIFT PRIME Studies. AJNR Am J Neuroradiol 37(4):667–672. https://doi.org/10.3174/ajnr.A4591ajnr.A4591 [pii]

Saber H, Narayanan S, Palla M, Saver JL, Nogueira RG, Yoo AJ, Sheth SA (2018) Mechanical thrombectomy for acute ischemic stroke with occlusion of the M2 segment of the middle cerebral artery: a meta-analysis. J Neurointerv Surg 10(7):620–624. https://doi.org/10.1136/neurintsurg-2017-013515 CrossRefPubMed

10.

Menon B, Najm M, Al-Ajlan F, Almekhlafi M, Puig J, Castellanos M, Dowlatshahi D, Calleja A, Sohn S, Ahn S (2018) 7 outcomes of medically-treated patients with M2-segment middle cerebral artery occlusion. Results from the prospective multicentral international cohort study INTERRSeCT. British Medical Journal Publishing Group,

11.

Menon B, Brown S, Almekhlafi M, Dippel D, Campbell B, Mitchell P, Hill M, Demchuk A, Jovin T, Davalos A (2018) 6 efficacy of endovascular thrombectomy in patients with M2 segment middle cerebral artery occlusions: meta-analysis of data from the HERMES collaboration. British Medical Journal Publishing Group,

12.

Shireman TI, Wang K, Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, Albers GW, Cognard C, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Devlin TG, Lopes DK, Reddy VK, du Mesnil de Rochemont R, Jahan R, Vilain KA, House J, Lee JM, Cohen DJ, Investigators S-P (2017) Cost-effectiveness of solitaire stent retriever thrombectomy for acute ischemic stroke: results from the SWIFT-PRIME trial (solitaire with the intention for thrombectomy as primary endovascular treatment for acute ischemic stroke). Stroke 48(2):379–387. https://doi.org/10.1161/STROKEAHA.116.014735 CrossRefPubMed

13.

Boudour S, Barral M, Gory B, Giroudon C, Aulagner G, Schott AM, Turjman F, Viprey M, Armoiry X (2018) A systematic review of economic evaluations on stent-retriever thrombectomy for acute ischemic stroke. J Neurol 265(7):1511–1520. https://doi.org/10.1007/s00415-018-8760-810.1007/s00415-018-8760-8 [pii]

14.

Sevick LK, Ghali S, Hill MD, Danthurebandara V, Lorenzetti DL, Noseworthy T, Spackman E, Clement F (2017) Systematic review of the cost and cost-effectiveness of rapid endovascular therapy for acute ischemic stroke. Stroke 48 (9):2519–2526. https://doi.org/10.1161/STROKEAHA.117.017199

15.

Saver JL, Goyal M, van der Lugt A, Menon BK, Majoie CB, Dippel DW, Campbell BC, Nogueira RG, Demchuk AM, Tomasello A, Cardona P, Devlin TG, Frei DF, du Mesnil de Rochemont R, Berkhemer OA, Jovin TG, Siddiqui AH, van Zwam WH, Davis SM, Castano C, Sapkota BL, Fransen PS, Molina C, van Oostenbrugge RJ, Chamorro A, Lingsma H, Silver FL, Donnan GA, Shuaib A, Brown S, Stouch B, Mitchell PJ, Davalos A, Roos YB, Hill MD, Collaborators H (2016) Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke: a meta-analysis. JAMA 316(12):1279–1288. https://doi.org/10.1001/jama.2016.13647 CrossRefPubMed

16.

d'Esterre CD, Boesen ME, Ahn SH, Pordeli P, Najm M, Minhas P, Davari P, Fainardi E, Rubiera M, Khaw AV, Zini A, Frayne R, Hill MD, Demchuk AM, Sajobi TT, Forkert ND, Goyal M, Lee TY, Menon BK (2015) Time-dependent computed tomographic perfusion thresholds for patients with acute ischemic stroke. Stroke 46(12):3390–3397. https://doi.org/10.1161/STROKEAHA.115.009250 CrossRefPubMed

17.

Hill MD, Goyal M, Demchuk AM, Fisher M (2015) Ischemic stroke tissue-window in the new era of endovascular treatment. Stroke 46(8):2332–2334. https://doi.org/10.1161/STROKEAHA.115.009688 CrossRefPubMed

18.

Goyal M, Demchuk AM, Menon BK, Eesa M, Rempel JL, Thornton J, Roy D, Jovin TG, Willinsky RA, Sapkota BL, Dowlatshahi D, Frei DF, Kamal NR, Montanera WJ, Poppe AY, Ryckborst KJ, Silver FL, Shuaib A, Tampieri D, Williams D, Bang OY, Baxter BW, Burns PA, Choe H, Heo JH, Holmstedt CA, Jankowitz B, Kelly M, Linares G, Mandzia JL, Shankar J, Sohn SI, Swartz RH, Barber PA, Coutts SB, Smith EE, Morrish WF, Weill A, Subramaniam S, Mitha AP, Wong JH, Lowerison MW, Sajobi TT, Hill MD, Investigators ET (2015) Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 372(11):1019–1030. https://doi.org/10.1056/NEJMoa1414905 CrossRefPubMed

19.

Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, Albers GW, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Baxter BW, Devlin TG, Lopes DK, Reddy VK, du Mesnil de Rochemont R, Singer OC, Jahan R, Investigators SP (2015) Stent-retriever thrombectomy after intravenous t-PA vs t-PA alone in stroke. N Engl J Med 372(24):2285–2295. https://doi.org/10.1056/NEJMoa1415061 CrossRefPubMed

20.

Albers GW, Goyal M, Jahan R, Bonafe A, Diener HC, Levy EI, Pereira VM, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Baxter BW, Devlin TG, Lopes DK, Reddy VK, de Rochemont Rdu M, Singer OC, Bammer R, Saver JL (2016) Ischemic core and hypoperfusion volumes predict infarct size in SWIFT PRIME. Ann Neurol 79(1):76–89. https://doi.org/10.1002/ana.24543 CrossRefPubMed

21.

Goyal M, Jadhav AP, Bonafe A, Diener H, Mendes Pereira V, Levy E, Baxter B, Jovin T, Jahan R, Menon BK, Saver JL, investigators SP (2016) Analysis of workflow and time to treatment and the effects on outcome in endovascular treatment of acute ischemic stroke: results from the SWIFT PRIME randomized controlled trial. Radiology 279(3):888–897. https://doi.org/10.1148/radiol.2016160204 CrossRefPubMed

22.

Menon BK, Sajobi TT, Zhang Y, Rempel JL, Shuaib A, Thornton J, Williams D, Roy D, Poppe AY, Jovin TG, Sapkota B, Baxter BW, Krings T, Silver FL, Frei DF, Fanale C, Tampieri D, Teitelbaum J, Lum C, Dowlatshahi D, Eesa M, Lowerison MW, Kamal NR, Demchuk AM, Hill MD, Goyal M (2016) Analysis of workflow and time to treatment on thrombectomy outcome in the endovascular treatment for small core and proximal occlusion ischemic stroke (ESCAPE) randomized, Controlled Trial. Circulation 133(23):2279–2286. https://doi.org/10.1161/CIRCULATIONAHA.115.019983 CrossRefPubMed

23.

Roman LS, Menon BK, Blasco J, Hernandez-Perez M, Davalos A, Majoie C, BCV C, Guillemin F, Lingsma H, Anxionnat R, Epstein J, Saver JL, Marquering H, Wong JH, Lopes D, Reimann G, Desal H, DWJ D, Coutts S, du Mesnil de Rochemont R, Yavagal D, Ferre JC, Roos Y, Liebeskind DS, Lenthall R, Molina C, Al Ajlan FS, Reddy V, Dowlatshahi D, Nader-Antoine S, Oppenheim C, Mitha AP, Davis SM, Weimar C, van Oostenbrugge RJ, Cobo E, Kleinig TJ, Donnan GA, van der Lugt A, Demchuk AM, Berkhemer OA, AMM B, Ford GA, Muir KW, Brown BS, Jovin T, van Zwam WH, Mitchell PJ, Hill MD, White P, Bracard S, Goyal M (2018) Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data. Lancet Neurol 17(10):895–904. https://doi.org/10.1016/S1474-4422(18)30242-4 CrossRefPubMed

24.

Goyal M, Menon BK, Almekhlafi MA, Demchuk A, Hill MD (2017) The need for better data on patients with acute stroke who are not treated because of unfavorable imaging. AJNR Am J Neuroradiol 38(3):424–425. https://doi.org/10.3174/ajnr.A5094 CrossRefPubMedPubMedCentral

25.

Goyal M, Jadhav AP (2017) Denominator fallacy revisited. J Neurointerv Surg 9(10):915–916CrossRefPubMed

26.

Goyal M, Menon BK, Krings T, Patil S, Qazi E, McTaggart RA, Almekhlafi MA, Jehan R, Saver J, Jayaraman MV (2016) What constitutes the M1 segment of the middle cerebral artery?. J Neurointerv Surg. https://doi.org/10.1136/neurintsurg-2015-012191

27.

Goyal M, Jadhav AP, Bonafe A, Diener H, Mendes Pereira V, Levy E, Baxter B, Jovin T, Jahan R, Menon BK, Saver JL (2016) Analysis of workflow and time to treatment and the effects on outcome in endovascular treatment of acute ischemic stroke: results from the SWIFT PRIME randomized controlled trial. Radiology 279(3):888–897. https://doi.org/10.1148/radiol.2016160204 CrossRefPubMed

28.

McTaggart RA, Yaghi S, Baird G, Haas RA, Jayaraman MV (2017) Decreasing procedure times with a standardized approach to ELVO cases. J Neurointerv Surg 9(1):2–5. https://doi.org/10.1136/neurintsurg-2016-012518 CrossRefPubMed

29.

Lapergue B, Blanc R, Gory B, Labreuche J, Duhamel A, Marnat G, Saleme S, Costalat V, Bracard S, Desal H, Mazighi M, Consoli A, Piotin M, Investigators AT (2017) Effect of endovascular contact aspiration vs stent retriever on revascularization in patients with acute ischemic stroke and large vessel occlusion: the ASTER randomized clinical trial. JAMA 318(5):443–452. https://doi.org/10.1001/jama.2017.9644 CrossRefPubMedPubMedCentral

30.

Mitha AP, Almekhlafi MA, Janjua MJ, Albuquerque FC, McDougall CG (2013) Simulation and augmented reality in endovascular neurosurgery: lessons from aviation. Neurosurgery 72(Suppl 1):107–114. https://doi.org/10.1227/NEU.0b013e31827981fd CrossRefPubMed

31.

Venema E, Mulder M, Roozenbeek B, Broderick JP, Yeatts SD, Khatri P, Berkhemer OA, Emmer BJ, Roos Y, Majoie C, van Oostenbrugge RJ, van Zwam WH, van der Lugt A, Steyerberg EW, Dippel DWJ, Lingsma HF (2017) Selection of patients for intra-arterial treatment for acute ischaemic stroke: development and validation of a clinical decision tool in two randomised trials. BMJ 357:j1710. https://doi.org/10.1136/bmj.j1710

32.

Nam HS, Lee KY, Han SW, Kim SH, Lee JY, Ahn SH, Kim DJ, Kim DI, Nam CM, Heo JH (2009) Prediction of long-term outcome by percent improvement after the first day of thrombolytic treatment in stroke patients. J Neurol Sci 281(1–2):69–73. https://doi.org/10.1016/j.jns.2009.02.365 CrossRefPubMed

33.

Heidenreich PA, Trogdon JG, Khavjou OA, Butler J, Dracup K, Ezekowitz MD, Finkelstein EA, Hong Y, Johnston SC, Khera A, Lloyd-Jones DM, Nelson SA, Nichol G, Orenstein D, Wilson PW, Woo YJ (2011) Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation 123(8):933–944. https://doi.org/10.1161/CIR.0b013e31820a55f5 CrossRefPubMed

34.

Aronsson M, Persson J, Blomstrand C, Wester P, Levin LA (2016) Cost-effectiveness of endovascular thrombectomy in patients with acute ischemic stroke. Neurology 86(11):1053–1059. https://doi.org/10.1212/WNL.0000000000002439 CrossRefPubMed

Titel: Which patients with acute stroke due to proximal occlusion should not be treated with endovascular thrombectomy?
verfasst von: Mayank Goyal
Mohammed A. Almekhlafi
Christoph Cognard
Ryan McTaggart
Kristine Blackham
Alessandra Biondi
Aad van der Lugt
Charles B. L. M. Majoie
Wim H. van Zwam
H. Bart van der Worp
Michael D. Hill
Publikationsdatum: 25.10.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Neuroradiology / Ausgabe 1/2019
Print ISSN: 0028-3940
Elektronische ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-018-2117-y

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Which patients with acute stroke due to proximal occlusion should not be treated with endovascular thrombectomy?

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