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Erschienen in: Brain Structure and Function 4/2020

13.02.2020 | Original Article

White matter correlates of hemi-face dominance in happy and sad expression

verfasst von: Stefano Ioannucci, Nathalie George, Patrick Friedrich, Leonardo Cerliani, Michel Thiebaut de Schotten

Erschienen in: Brain Structure and Function | Ausgabe 4/2020

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Abstract

The neural underpinnings of human emotional expression are thought to be unevenly distributed among the two brain hemispheres. However, little is known on the anatomy supporting this claim, particularly in the cerebral white matter. Here, we explored the relationship between hemi-face dominance in emotional expression and cerebral white matter asymmetries in 33 healthy participants. Measures of emotional expression were derived from pictures of the participant’s faces in a ‘happy smiling’ and a ‘sad frowning’ conditions. Chimeric faces were constructed by mirroring right and left hemi-faces, as done in previous studies, resulting in a left mirrored and right mirrored chimeric face per picture. To gain measures of hemi-face dominance per participant, a jury of 20 additional participants rated which chimeric face shows the higher intensity of emotional expressivity, by marking a 155 mm line between the two versions. Measures of the asymmetry of the uncinate, the cingulum and the three branches of superior longitudinal fasciculi were derived from diffusion-weighted imaging tractography dissections. Group effect analyses indicated that the degree of asymmetry in emotional expression was not as prominent as reported in the literature and showed a large inter-individual variability. The degree of asymmetry in emotional expression was, however, significantly associated with the asymmetries in connective properties of the fronto-temporal and fronto-parietal tracts, specifically the uncinate fasciculus and the first branch of the superior longitudinal fasciculus. Therefore, this result raises novel hypotheses on the relationship of specific white matter tracts and emotional expression, especially their role in mood disorders.
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Metadaten
Titel
White matter correlates of hemi-face dominance in happy and sad expression
verfasst von
Stefano Ioannucci
Nathalie George
Patrick Friedrich
Leonardo Cerliani
Michel Thiebaut de Schotten
Publikationsdatum
13.02.2020
Verlag
Springer Berlin Heidelberg
Erschienen in
Brain Structure and Function / Ausgabe 4/2020
Print ISSN: 1863-2653
Elektronische ISSN: 1863-2661
DOI
https://doi.org/10.1007/s00429-020-02040-7

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