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European Journal of Clinical Microbiology & Infectious Diseases

Erschienen in:

12.11.2020 | Brief Report

Whole genome sequencing to decipher the virulence phenotype of hypervirulent Klebsiella pneumoniae responsible for liver abscess, Marseille, France

verfasst von: Sophie Alexandra Baron, Léa-Marie Pascale, Matthieu Million, Antoine Briantais, Jean-Marc Durand, Linda Hadjadj, Jean-Marc Rolain

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 5/2021

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Abstract

We described three clinical cases of pyogenic liver abscess caused by hypervirulent Klebsiella pneumoniae (hvKp) successfully treated by prolonged antibiotherapy, in which one case was complicated by endophthalmitis. Whole genome sequencing helped to confirm the diagnosis of these hvKp strains, which belong to clonal complexes CC86 and CC23 and carried hvKp-associated genes (magA and/or rmpA). This syndrome is increasingly reported in France and Europe and raises questions about the source of infection.

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Titel: Whole genome sequencing to decipher the virulence phenotype of hypervirulent Klebsiella pneumoniae responsible for liver abscess, Marseille, France
verfasst von: Sophie Alexandra Baron
Léa-Marie Pascale
Matthieu Million
Antoine Briantais
Jean-Marc Durand
Linda Hadjadj
Jean-Marc Rolain
Publikationsdatum: 12.11.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 5/2021
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-020-04080-7

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Whole genome sequencing to decipher the virulence phenotype of hypervirulent Klebsiella pneumoniae responsible for liver abscess, Marseille, France

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