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05.01.2022 | Original Contributions

Why Size Matters: an Evaluation of Gastric Pouch Size in Roux-en-Y Gastric Bypass Using CT Volumetric Analysis and its Effect on Marginal Ulceration

Erschienen in: Obesity Surgery | Ausgabe 3/2022

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Abstract

Purpose

Marginal ulceration (MU) is a common long-term complication following Roux-en-Y gastric bypass (RYGB). The causes of MU after RYGB are multifactorial and include surgical technique of constructing the gastrojejunal anastomosis (GJA). The purpose of this study is to evaluate the relationship between gastric pouch size in RYGB and MU using CT volumetrics.

Material and Methods

Patients were retrospectively identified who underwent esophagogastroduodenoscopy (EGD) following RYGB at a tertiary care teaching hospital. Measurement of gastric pouch size was performed using 3-D CT software. Standard statistical methods were used, a univariate comparison was performed between MU and non-MU patients followed by a propensity-matched comparison to control for factors known to affect MU, and a propensity-matched subgroup analysis was also performed.

Results

In total, 122 patients met criteria, 57 of which had MU on EGD and 65 who did not. The MU group had more smokers and patients with PPI use than the non-MU group, and the mean time from operation to CT scan was 26.6 months (range: 0–108 months). The MU group had a larger gastric pouch size than the non-MU group (34.1 ± 11.8 versus 20.1 ± 6.8 cm3). When analyzed for matched patient cohorts, this difference remained for the MU group that included smokers and PPI use. When stratified for pouch size, for each 5 cm3 increase in pouch size, patients had 2.4 times odds increase of MU formation.

Conclusions

CT volumetric analysis demonstrated that a larger gastric pouch size was associated with MU following RYGB.

Graphical abstract

Literatur
2.
Zurück zum Zitat Schauer PR, Bhatt DL, Kirwan JP, et al. Bariatric surgery versus intensive medical therapy for diabetes — 5-year outcomes. N Engl J Med [Internet]. New England Journal of Medicine (NEJM/MMS); 2017 [cited 2021 Apr 25];376:641–51. Available from: https://pubmed.ncbi.nlm.nih.gov/28199805/. Schauer PR, Bhatt DL, Kirwan JP, et al. Bariatric surgery versus intensive medical therapy for diabetes — 5-year outcomes. N Engl J Med [Internet]. New England Journal of Medicine (NEJM/MMS); 2017 [cited 2021 Apr 25];376:641–51. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​28199805/​.
3.
Zurück zum Zitat Olbers T, Lönroth H, Fagevik-Olsén M, et al. Laparoscopic gastric bypass: development of technique, respiratory function, and long-term outcome. Obes Surg. 2003;13:364–70.CrossRef Olbers T, Lönroth H, Fagevik-Olsén M, et al. Laparoscopic gastric bypass: development of technique, respiratory function, and long-term outcome. Obes Surg. 2003;13:364–70.CrossRef
7.
8.
Zurück zum Zitat Byrne TK. Complications of surgery for obesity. Surg Clin North Am. W.B. Saunders; 2001;81:1181–93. Byrne TK. Complications of surgery for obesity. Surg Clin North Am. W.B. Saunders; 2001;81:1181–93.
11.
Zurück zum Zitat Almby K, Edholm D. Anastomotic strictures after Roux-en-Y gastric bypass: a cohort study from the Scandinavian obesity surgery registry. Obes Surg. 2019;29:172–7.CrossRef Almby K, Edholm D. Anastomotic strictures after Roux-en-Y gastric bypass: a cohort study from the Scandinavian obesity surgery registry. Obes Surg. 2019;29:172–7.CrossRef
14.
Zurück zum Zitat Siilin H, Wanders A, Gustavsson S, et al. The proximal gastric pouch invariably contains acid-producing parietal cells in Roux-en-Y gastric bypass. Obes Surg [Internet]. FD Communications Inc.; 2005 [cited 2021 Apr 21];15:771–7. Available from: https://pubmed.ncbi.nlm.nih.gov/15978145/. Siilin H, Wanders A, Gustavsson S, et al. The proximal gastric pouch invariably contains acid-producing parietal cells in Roux-en-Y gastric bypass. Obes Surg [Internet]. FD Communications Inc.; 2005 [cited 2021 Apr 21];15:771–7. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​15978145/​.
15.
Zurück zum Zitat Edholm D, Ottosson J, Sundbom M. Importance of pouch size in laparoscopic Roux-en-Y gastric bypass: a cohort study of 14,168 patients. Surg Endosc. Springer US; 2016;30:2011–5. Edholm D, Ottosson J, Sundbom M. Importance of pouch size in laparoscopic Roux-en-Y gastric bypass: a cohort study of 14,168 patients. Surg Endosc. Springer US; 2016;30:2011–5.
16.
Zurück zum Zitat Coblijn UK, Lagarde SM, de Castro SMM, et al. Symptomatic marginal ulcer disease after Roux-en-Y gastric bypass: incidence, risk factors and management. Obes Surg. 2015;25:805–11.CrossRef Coblijn UK, Lagarde SM, de Castro SMM, et al. Symptomatic marginal ulcer disease after Roux-en-Y gastric bypass: incidence, risk factors and management. Obes Surg. 2015;25:805–11.CrossRef
17.
Zurück zum Zitat Coblijn UK, Goucham AB, Lagarde SM, et al. Development of ulcer disease after Roux-en-Y gastric bypass, incidence, risk factors, and patient presentation: a systematic review [Internet]. Obes. Surg. Obes Surg; 2014 [cited 2021 Apr 21]. p. 299–309. Available from: https://pubmed.ncbi.nlm.nih.gov/24234733/. Coblijn UK, Goucham AB, Lagarde SM, et al. Development of ulcer disease after Roux-en-Y gastric bypass, incidence, risk factors, and patient presentation: a systematic review [Internet]. Obes. Surg. Obes Surg; 2014 [cited 2021 Apr 21]. p. 299–309. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​24234733/​.
18.
Zurück zum Zitat Wennerlund J, Gunnarsson U, Strigård K, et al. Acid-related complications after laparoscopic Roux-en-Y gastric bypass: risk factors and impact of proton pump inhibitors. Surg Obes Relat Dis. 2020;16:620–5.CrossRef Wennerlund J, Gunnarsson U, Strigård K, et al. Acid-related complications after laparoscopic Roux-en-Y gastric bypass: risk factors and impact of proton pump inhibitors. Surg Obes Relat Dis. 2020;16:620–5.CrossRef
19.
Zurück zum Zitat Suggs WJ, Kouli W, Lupovici M, et al. Complications at gastrojejunostomy after laparoscopic Roux-en-Y gastric bypass: comparison between 21- and 25-mm circular staplers. Surg Obes Relat Dis. Elsevier; 2007;3:508–14. Suggs WJ, Kouli W, Lupovici M, et al. Complications at gastrojejunostomy after laparoscopic Roux-en-Y gastric bypass: comparison between 21- and 25-mm circular staplers. Surg Obes Relat Dis. Elsevier; 2007;3:508–14.
20.
Zurück zum Zitat Sundaresan N, Sullivan M, Hiticas BA, et al. Impacts of gastrojejunal anastomotic technique on rates of marginal ulcer formation and anastomotic bleeding following Roux-en-Y gastric bypass. Obes Surg. 2021;31:2921–6.CrossRef Sundaresan N, Sullivan M, Hiticas BA, et al. Impacts of gastrojejunal anastomotic technique on rates of marginal ulcer formation and anastomotic bleeding following Roux-en-Y gastric bypass. Obes Surg. 2021;31:2921–6.CrossRef
22.
Zurück zum Zitat Bonanno A, Tieu B, Dewey E, et al. Thoracoscopic truncal vagotomy versus surgical revision of the gastrojejunal anastomosis for recalcitrant marginal ulcers. Surg Endosc. Springer New York LLC; 2019;33:607–11. Bonanno A, Tieu B, Dewey E, et al. Thoracoscopic truncal vagotomy versus surgical revision of the gastrojejunal anastomosis for recalcitrant marginal ulcers. Surg Endosc. Springer New York LLC; 2019;33:607–11.
23.
Zurück zum Zitat Wu Chao Ying V, Song SH, J. Khan K, et al. Prophylactic PPI help reduce marginal ulcers after gastric bypass surgery: a systematic review and meta-analysis of cohort studies. Surg Endosc [Internet]. Springer New York LLC; 2015 [cited 2021 Apr 21];29:1018–23. Available from: https://pubmed.ncbi.nlm.nih.gov/25159641/. Wu Chao Ying V, Song SH, J. Khan K, et al. Prophylactic PPI help reduce marginal ulcers after gastric bypass surgery: a systematic review and meta-analysis of cohort studies. Surg Endosc [Internet]. Springer New York LLC; 2015 [cited 2021 Apr 21];29:1018–23. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​25159641/​.
Metadaten
Titel
Why Size Matters: an Evaluation of Gastric Pouch Size in Roux-en-Y Gastric Bypass Using CT Volumetric Analysis and its Effect on Marginal Ulceration
Publikationsdatum
05.01.2022
Erschienen in
Obesity Surgery / Ausgabe 3/2022
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-021-05850-8

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