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Erschienen in: Der Nervenarzt 3/2017

01.06.2016 | Morbus Alzheimer | Übersichten

Wie Schlaf und Alzheimer-Krankheit zusammenhängen

Insomnie, Amnesie und Amyloid

verfasst von: Dr. Dr. M. A. Busche, M. Kekuš, H. Förstl

Erschienen in: Der Nervenarzt | Ausgabe 3/2017

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Zusammenfassung

Schlaf spielt eine essenzielle Rolle bei der Gedächtniskonsolidierung. Störungen des Schlafs sind im Verlauf der Alzheimer-Krankheit zwar häufig, gelten bislang aber eher als „Nebenschauplatz“ und nicht als wesentliches Merkmal der Krankheit. Neueste Erkenntnisse der experimentellen Forschung zeigen jedoch, dass Schlafstörungen nicht nur den typischen kognitiven Defiziten vorangehen, sondern sogar im Zusammenhang mit der Pathogenese der Alzheimer-Krankheit stehen sowie Symptome und Verlauf entscheidend beeinflussen können. Schlafstörungen verdienen daher als potenziell modifizierbare Risikofaktoren der Alzheimer-Krankheit mehr Aufmerksamkeit in Forschung, Diagnostik und Therapie.
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Metadaten
Titel
Wie Schlaf und Alzheimer-Krankheit zusammenhängen
Insomnie, Amnesie und Amyloid
verfasst von
Dr. Dr. M. A. Busche
M. Kekuš
H. Förstl
Publikationsdatum
01.06.2016
Verlag
Springer Medizin
Erschienen in
Der Nervenarzt / Ausgabe 3/2017
Print ISSN: 0028-2804
Elektronische ISSN: 1433-0407
DOI
https://doi.org/10.1007/s00115-016-0122-0

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