Background
Methods
Study design and sampling
Preference elicitation scenarios
No. | Disease | EQ-6D-5L | Course of disease over time |
---|---|---|---|
1 | Otitis media, yearly recurrent (chronic otitis media) | 112,412 | Recurrent |
2 | Migraine, monthly recurrent | 124,413 | Recurrent |
3 | Allergic rhinitis, seasonal (hay fever), yearly recurrent | 111,211 | Recurrent |
4 | Gastritis, 6 months, untreated (inflammation of the stomach lining) | 112,311 | Recurrent |
5 | Cystitis, chronic recurrent (recurrent cystitis) | 112,311 | Recurrent |
6 | Athlete’s foot, untreated (tinea pedis) | 111,211 | Chronic |
7 | Infection of the nails, chronic, untreated, onychomycosis | 111,211 | Chronic |
8 | Eczema, chronic permanent (dermatitis atopic) | 112,211 | Chronic |
9 | Back and neck pain | 322,311 | Chronic |
10 | Depression, mild | 112,131 | Chronic |
11 | CVA/stroke, moderate impairments | 333,323 | Chronic |
12 | Dementia, severe | 345,235 | Chronic |
13 | Hip fracture | 444,311 | Chronic |
14 | Spinal cord lesion, low (stable phase) | 544,321 | Chronic |
Preference elicitation techniques
Data analysis
Results
Descriptive statistics
No. of respondents | 1002 |
Mean age (year) (std. dev.) | 43.36 (15.6) |
Range (year) | 18–79 |
Male gender (%) | 408 (40.7) |
Married (%) | 731 (71.2) |
Head of household (%) | 372 (37.1) |
Household size (std. dev.) | 3.3 (1.2) |
Education | |
Elementary education ≤ 5 years | 218 (21.8) |
Secondary education ≤ 8 years | 107 (10.7) |
High school diploma ≤ 12 years | 348 (34.8) |
University education | 328 (32.7) |
Monthly household cost group (US$) | |
Less than 167 | 248 (24.7) |
167–333 | 473 (47.2) |
333–667 | 232 (23.1) |
667–1000 | 29 (2.9) |
More than 1000 | 20 (2.0) |
Hospitalization and near-death experience from a year before | |
Individual experience (%) | 109 (10.9) |
Family member experience (%) | 131 (13.0) |
Near-death experience (%) | 50 (5) |
Having a chronic disease | |
Individual experience (%) | 61 (6.1) |
Family member experience (%) | 102 (10.2) |
Concurrent | 41 (4.1) |
Health and WTP preferences of respondents
Scenario | Spinal cord lesion | Depression | Eczema | Otitis media | Cystitis | Gastritis | Back and neck pain | Allergic rhinitis | Dementia | CVA | Hip fracture | Migraine |
---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of respondents | 334 | 334 | 334 | 334 | 323 | 334 | 334 | 334 | 334 | 334 | 334 | 334 |
VAS (current health state) | 0.76 | 0.76 | 0.76 | 0.76 | 0.77 | 0.78 | 0.75 | 0.77 | 0.75 | 0.78 | 0.76 | 0.76 |
VAS (disease) | 0.2 | 0.48 | 0.6 | 0.6 | 0.52 | 0.58 | 0.43 | 0.63 | 0.3 | 0.22 | 0.51 | 0.57 |
TTO-adjusted (disease) | 0.49 | 0.86 | 0.95 | 0.96 | 0.9 | 0.92 | 0.89 | 0.97 | 0.51 | 0.52 | 0.87 | 0.93 |
Rate of traders in TTO-adjusted | 97% | 75% | 37% | 31% | 63% | 52% | 59% | 28% | 96% | 97% | 63% | 46% |
TTO-10 year (disease) | 0.47 | 0.89 | 0.96 | 0.97 | 0.91 | 0.94 | 0.89 | 0.97 | 0.51 | 0.52 | 0.88 | 0.94 |
Rate of traders in 10 year-TTO | 97% | 46% | 20% | 18% | 38% | 29% | 43% | 16% | 94% | 98% | 43% | 24% |
Positive WTP | 93% | 90% | 84% | 83% | 90% | 87% | 87% | 82% | 88% | 92% | 89% | 85% |
Zero WTP | 7% | 10% | 16% | 17% | 10% | 13% | 13% | 18% | 12% | 8% | 11% | 15% |
Min WTP-non-zero value (U$) | 15 | 10 | 10 | 10 | 15 | 10 | 13 | 10 | 10 | 33 | 17 | 300,000 |
Max WTP (US$) | 166,667 | 43,333 | 10,000 | 16,667 | 25,000 | 16,667 | 16,667 | 16,667 | 233,333 | 116,667 | 25,000 | 83,333 |
Mean WTP (US$) | 11,215 | 2013 | 675 | 560 | 2096 | 1243 | 977 | 579 | 7357 | 11,944 | 2178 | 1471 |
Mean WTP for QALY in 12 disease scenarios
Health instrument | Scenario | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Spinal cord lesion | Depression | Eczema | Otitis media | Cystitis | Gastritis | Back and neck pain | Allergic rhinitis | Dementia | CVA | Hip fracture | Migraine | |
VAS | ||||||||||||
WTP/QALY | 1450 | 539 | 373 | 329 | 802 | 541 | 305 | 367 | 1672 | 1688 | 753 | 530 |
% GDP** | 0.30 | 0.11 | 0.08 | 0.07 | 0.17 | 0.11 | 0.06 | 0.08 | 0.35 | 0.35 | 0.16 | 0.11 |
TTO-adjusted | ||||||||||||
WTP/QALY | 2102 | 1273 | 1841 | 1195 | 1921 | 1659 | 1032 | 1152 | 1667 | 2666 | 2067 | 1599 |
% GDP** | 0.44 | 0.27 | 0.39 | 0.25 | 0.40 | 0.35 | 0.22 | 0.24 | 0.35 | 0.56 | 0.43 | 0.34 |
TTO 10-year | ||||||||||||
WTP/QALY | 1827 | 1220 | 634 | 1301 | 1327 | 838 | 742 | 606 | 1855 | 2402 | 1912 | 1306 |
% GDP** | 0.38 | 0.26 | 0.13 | 0.27 | 0.28 | 0.18 | 0.16 | 0.13 | 0.39 | 0.50 | 0.40 | 0.27 |
Variable | Disease | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Spinal cord lesion | Depression | Dementia | Eczema | Gastritis | Migraine | Hip fracture | CVA | Allergic rhinitis | Back and neck pain | Cystitis | Otitis media | |
Income | 1.04* | 0.89* | –*** | 1.17** | – | – | 0.70* | 1.08* | – | – | 0.52* | 1.55** |
Education | 0.68* | 0.69* | 0.70* | 0.87** | 0.65* | 0.37** | 0.76* | 0.90* | 0.94** | 0.83* | 0.42** | 1.14** |
Marriage | 0.74** | 1.18* | – | – | 1.29* | – | – | – | – | – | 1.60* | – |
Disease/health state | – | – | 1.62** | 4.85** | 4.42* | 7.29* | – | 2.35** | − 9.5* | – | 3.32* | – |
Head of household | – | − 1.39** | – | – | – | – | – | – | – | – | – | – |
Familiarity with disease | – | – | − 1.76* | - | – | – | – | – | – | – | – | – |
Gender | – | – | – | – | – | – | – | – | – | – | 1.17* | – |
Household size | – | – | – | – | – | – | – | – | – | – | – | 0.73** |