World Journal of Pediatrics

Newborn screening (NBS) is a prerequisite for early diagnosis and successful treatment of many severe conditions presenting in the neonatal period or infancy. The German NBS panel currently includes 15 target disorders, including 12 metabolic …

Mycoplasma pneumoniae (MP) is the common pathogens leading to community-acquired pneumonia (CAP) in children [ 1 , 2 ]. M. pneumoniae pneumonia (MPP) is generally recognized as a self-limiting illness, but sometimes it will develop into refractory …

S100 proteins, found only in vertebrates [ 1 ], are low molecular weight proteins with two Ca 2+ binding sites of EF-hand type [ 2 ]. Another ion, which is bound by these proteins and is intensively studied, is Zn 2+ ; thanks to this, S100 proteins …

Viral bronchiolitis is the most common reason that infants in the developed world are admitted to the hospital [ 1 ]. Variations in innate immunity, which regulate inflammatory reactions and development of adaptive immunity, may be the reason why …