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Erschienen in: Die Unfallchirurgie 6/2022

23.05.2022 | Osteoporose | Leitthema

Zementaugmentation in der Wirbelsäulenchirurgie

verfasst von: Dr. med. Philipp Schleicher, Alexander Wengert, Jonathan Neuhoff, Frank Kandziora

Erschienen in: Die Unfallchirurgie | Ausgabe 6/2022

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Zusammenfassung

Knochenzement wird an der Wirbelsäule schon seit 50 Jahren verwendet. In der modernen Wirbelsäulenchirurgie sind die Zementaugmentation osteoporotisch frakturierter Wirbelkörper in Form der Vertebroplastie/Kyphoplastie sowie die Zementaugmentation von Pedikelschrauben bei instrumentierten Eingriffen jedweder Ätiologie als Standardverfahren etabliert. Beide Verfahren sind sehr effektiv, wobei der Nutzen der Vertebroplastie/Kyphoplastie in der Vergangenheit sehr kontrovers diskutiert wurde. Insgesamt treten selten Komplikationen auf. Die relevanteste Komplikation ist die Zementleckage, die in der Mehrzahl der Fälle asymptomatisch bleibt, im schlimmsten Fall aber auch neurologische Schäden oder embolische Ereignisse bis hin zum Kreislaufversagen nach sich ziehen kann. Der Prophylaxe der Zementextravasation kommt daher überragende Bedeutung zu. Risikofaktoren für die Zementleckage und vorbeugende Maßnahmen werden anhand der vorhandenen Literatur in einem umfassenden Review dargestellt.
Literatur
1.
Zurück zum Zitat Brattström H, Granholm L (2009) Atlanto-axial fusion in rheumatoid arthritis a new method of fixation with wire and bone cement. Acta Orthop Scand 47(6):619–628CrossRef Brattström H, Granholm L (2009) Atlanto-axial fusion in rheumatoid arthritis a new method of fixation with wire and bone cement. Acta Orthop Scand 47(6):619–628CrossRef
2.
Zurück zum Zitat Park JB, Rouse GP, Kenner GH, Gendreau CL (2009) Spinal fixation using acrylic bone cement: mechanical property measurements. Biomater Med Devices Artif Organs 6(1):77–84CrossRef Park JB, Rouse GP, Kenner GH, Gendreau CL (2009) Spinal fixation using acrylic bone cement: mechanical property measurements. Biomater Med Devices Artif Organs 6(1):77–84CrossRef
3.
Zurück zum Zitat Galibert P, Deramond H, Rosat P, Gars DL (1987) Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirurgie 33(2):166–168PubMed Galibert P, Deramond H, Rosat P, Gars DL (1987) Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirurgie 33(2):166–168PubMed
4.
Zurück zum Zitat Garfin SR, Yuan HA, Reiley MA (2001) New technologies in spine. Spine 26(14):1511–1515PubMedCrossRef Garfin SR, Yuan HA, Reiley MA (2001) New technologies in spine. Spine 26(14):1511–1515PubMedCrossRef
5.
Zurück zum Zitat Lieberman IH, Dudeney S, Reinhardt M‑K, Bell G (2001) Initial outcome and efficacy of “kyphoplasty” in the treatment of painful osteoporotic vertebral compression fractures. Spine 26(14):1631–1637PubMedCrossRef Lieberman IH, Dudeney S, Reinhardt M‑K, Bell G (2001) Initial outcome and efficacy of “kyphoplasty” in the treatment of painful osteoporotic vertebral compression fractures. Spine 26(14):1631–1637PubMedCrossRef
6.
Zurück zum Zitat Hillmeier J, Meeder PJ, Nöldge G, Kasperk C (2003) Minimal invasive Reposition und innere Stabilisierung osteoporotischer Wirbelkörperfrakturen (Ballonikyphoplastie). Orthop Traumatol 15(4):343–362CrossRef Hillmeier J, Meeder PJ, Nöldge G, Kasperk C (2003) Minimal invasive Reposition und innere Stabilisierung osteoporotischer Wirbelkörperfrakturen (Ballonikyphoplastie). Orthop Traumatol 15(4):343–362CrossRef
7.
Zurück zum Zitat Taylor RS, Fritzell P, Taylor RJ (2007) Balloon kyphoplasty in the management of vertebral compression fractures: an updated systematic review and meta-analysis. Eur Spine J 16(8):1085–1100PubMedPubMedCentralCrossRef Taylor RS, Fritzell P, Taylor RJ (2007) Balloon kyphoplasty in the management of vertebral compression fractures: an updated systematic review and meta-analysis. Eur Spine J 16(8):1085–1100PubMedPubMedCentralCrossRef
8.
Zurück zum Zitat Mathis JM, Barr JD, Belkoff SM, Barr MS, Jensen ME, Deramond H (2001) Percutaneous vertebroplasty: a developing standard of care for vertebral compression fractures. AJNR Am J Neuroradiol 22(2):373–381PubMedPubMedCentral Mathis JM, Barr JD, Belkoff SM, Barr MS, Jensen ME, Deramond H (2001) Percutaneous vertebroplasty: a developing standard of care for vertebral compression fractures. AJNR Am J Neuroradiol 22(2):373–381PubMedPubMedCentral
9.
Zurück zum Zitat Weill A, Chiras J, Simon JM, Rose M, Sola-Martinez T, Enkaoua E (1996) Spinal metastases: indications for and results of percutaneous injection of acrylic surgical cement. Radiology 199(1):241–247PubMedCrossRef Weill A, Chiras J, Simon JM, Rose M, Sola-Martinez T, Enkaoua E (1996) Spinal metastases: indications for and results of percutaneous injection of acrylic surgical cement. Radiology 199(1):241–247PubMedCrossRef
10.
Zurück zum Zitat Heini PF, Berlemann U, Kaufmann M, Lippuner K, Fankhauser C, van Landuyt P (2001) Augmentation of mechanical properties in osteoporotic vertebral bones—a biomechanical investigation of vertebroplasty efficacy with different bone cements. Eur Spine J 10(2):164–171PubMedPubMedCentralCrossRef Heini PF, Berlemann U, Kaufmann M, Lippuner K, Fankhauser C, van Landuyt P (2001) Augmentation of mechanical properties in osteoporotic vertebral bones—a biomechanical investigation of vertebroplasty efficacy with different bone cements. Eur Spine J 10(2):164–171PubMedPubMedCentralCrossRef
11.
Zurück zum Zitat Cai T, Wang F, Nan L, Chen D, Wang S, Feng X et al (2021) Perioperative hidden blood loss in elderly osteoporotic vertebral compression fracture patients with percutaneous vertebroplasty and influencing factors. Geriatr Orthop Surg Rehabil 12:2151459321996178PubMedPubMedCentral Cai T, Wang F, Nan L, Chen D, Wang S, Feng X et al (2021) Perioperative hidden blood loss in elderly osteoporotic vertebral compression fracture patients with percutaneous vertebroplasty and influencing factors. Geriatr Orthop Surg Rehabil 12:2151459321996178PubMedPubMedCentral
12.
Zurück zum Zitat Klazen CA, Lohle PN, de Vries J, Jansen FH, Tielbeek AV, Blonk MC et al (2010) Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial. Lancet 376(9746):1085–1092PubMedCrossRef Klazen CA, Lohle PN, de Vries J, Jansen FH, Tielbeek AV, Blonk MC et al (2010) Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial. Lancet 376(9746):1085–1092PubMedCrossRef
13.
Zurück zum Zitat Hulme PA, Krebs J, Ferguson SJ, Berlemann U (2006) Vertebroplasty and kyphoplasty: a systematic review of 69 clinical studies. Spine 31(17):1983–2001PubMedCrossRef Hulme PA, Krebs J, Ferguson SJ, Berlemann U (2006) Vertebroplasty and kyphoplasty: a systematic review of 69 clinical studies. Spine 31(17):1983–2001PubMedCrossRef
14.
Zurück zum Zitat Dohm M, Black CM, Dacre A, Tillman JB, Fueredi G, KAVIAR investigators (2014) A randomized trial comparing balloon kyphoplasty and vertebroplasty for vertebral compression fractures due to osteoporosis. AJNR Am J Neuroradiol 35(12):2227–22236PubMedPubMedCentralCrossRef Dohm M, Black CM, Dacre A, Tillman JB, Fueredi G, KAVIAR investigators (2014) A randomized trial comparing balloon kyphoplasty and vertebroplasty for vertebral compression fractures due to osteoporosis. AJNR Am J Neuroradiol 35(12):2227–22236PubMedPubMedCentralCrossRef
15.
Zurück zum Zitat Hadjipavlou AG, Tzermiadianos MN, Katonis PG, Szpalski M (2005) Percutaneous vertebroplasty and balloon kyphoplasty for the treatment of osteoporotic vertebral compression fractures and osteolytic tumours. Bone Joint J 87(12):1595–1604 Hadjipavlou AG, Tzermiadianos MN, Katonis PG, Szpalski M (2005) Percutaneous vertebroplasty and balloon kyphoplasty for the treatment of osteoporotic vertebral compression fractures and osteolytic tumours. Bone Joint J 87(12):1595–1604
17.
Zurück zum Zitat Feng L, Shen J‑M, Feng C, Chen J, Wu Y (2017) Comparison of radiofrequency kyphoplasty (RFK) and balloon kyphoplasty (BKP) in the treatment of vertebral compression fractures. Medicine 96(25):e7150PubMedPubMedCentralCrossRef Feng L, Shen J‑M, Feng C, Chen J, Wu Y (2017) Comparison of radiofrequency kyphoplasty (RFK) and balloon kyphoplasty (BKP) in the treatment of vertebral compression fractures. Medicine 96(25):e7150PubMedPubMedCentralCrossRef
18.
Zurück zum Zitat Rotter R, Martin H, Fuerderer S, Gabl M, Roeder C, Heini P et al (2010) Vertebral body stenting: a new method for vertebral augmentation versus kyphoplasty. Eur Spine J 19(6):916–923PubMedPubMedCentralCrossRef Rotter R, Martin H, Fuerderer S, Gabl M, Roeder C, Heini P et al (2010) Vertebral body stenting: a new method for vertebral augmentation versus kyphoplasty. Eur Spine J 19(6):916–923PubMedPubMedCentralCrossRef
19.
Zurück zum Zitat Werner CML, Osterhoff G, Schlickeiser J, Jenni R, Wanner GA, Ossendorf C et al (2013) Vertebral body stenting versus kyphoplasty for the treatment of osteoporotic vertebral compression fractures. J Bone Joint Surg Am 95(7):577–584PubMedCrossRef Werner CML, Osterhoff G, Schlickeiser J, Jenni R, Wanner GA, Ossendorf C et al (2013) Vertebral body stenting versus kyphoplasty for the treatment of osteoporotic vertebral compression fractures. J Bone Joint Surg Am 95(7):577–584PubMedCrossRef
20.
Zurück zum Zitat Kim H‑J, Zuckerman SL, Cerpa M, Yeom JS, Lehman RA, Lenke LG (2020) Incidence and risk factors for complications and mortality after vertebroplasty or kyphoplasty in the osteoporotic vertebral compression fracture—analysis of 1,932 cases from the American college of surgeons national surgical quality improvement. Global Spine J. https://doi.org/10.1177/2192568220976355CrossRefPubMedPubMedCentral Kim H‑J, Zuckerman SL, Cerpa M, Yeom JS, Lehman RA, Lenke LG (2020) Incidence and risk factors for complications and mortality after vertebroplasty or kyphoplasty in the osteoporotic vertebral compression fracture—analysis of 1,932 cases from the American college of surgeons national surgical quality improvement. Global Spine J. https://​doi.​org/​10.​1177/​2192568220976355​CrossRefPubMedPubMedCentral
21.
22.
Zurück zum Zitat Schmidt R, Cakir B, Mattes T, Wegener M, Puhl W, Richter M (2005) Cement leakage during vertebroplasty: an underestimated problem? Eur Spine J 14(5):466–473PubMedPubMedCentralCrossRef Schmidt R, Cakir B, Mattes T, Wegener M, Puhl W, Richter M (2005) Cement leakage during vertebroplasty: an underestimated problem? Eur Spine J 14(5):466–473PubMedPubMedCentralCrossRef
23.
Zurück zum Zitat Sidhu GS, Kepler CK, Savage KE, Eachus B, Albert TJ, Vaccaro AR (2013) Neurological deficit due to cement extravasation following a vertebral augmentation procedure: case report. J Neurosurg Spine 19(1):61–70PubMedCrossRef Sidhu GS, Kepler CK, Savage KE, Eachus B, Albert TJ, Vaccaro AR (2013) Neurological deficit due to cement extravasation following a vertebral augmentation procedure: case report. J Neurosurg Spine 19(1):61–70PubMedCrossRef
24.
Zurück zum Zitat Guo H, Huang H, Shao Y, Qin Q, Liang D, Zhang S et al (2021) Risk factors for pulmonary cement embolism (PCE) after polymethylmethacrylate augmentation: analysis of 32 PCE cases. Neurospine 18(4):806–815PubMedPubMedCentralCrossRef Guo H, Huang H, Shao Y, Qin Q, Liang D, Zhang S et al (2021) Risk factors for pulmonary cement embolism (PCE) after polymethylmethacrylate augmentation: analysis of 32 PCE cases. Neurospine 18(4):806–815PubMedPubMedCentralCrossRef
25.
Zurück zum Zitat Zhang T, Wang Y, Zhang P, Xue F, Zhang D, Jiang B (2022) What are the risk factors for adjacent vertebral fracture after vertebral augmentation? A meta-analysis of published studies. Global Spine J 12(1):130–141PubMedCrossRef Zhang T, Wang Y, Zhang P, Xue F, Zhang D, Jiang B (2022) What are the risk factors for adjacent vertebral fracture after vertebral augmentation? A meta-analysis of published studies. Global Spine J 12(1):130–141PubMedCrossRef
26.
Zurück zum Zitat Nieuwenhuijse MJ, Muijs SPJ, van Erkel AR, Dijkstra SPD (2010) A clinical comparative study on low versus medium viscosity polymethylmetacrylate bone cement in percutaneous vertebroplasty. Spine 35(20):E1037–1044PubMedCrossRef Nieuwenhuijse MJ, Muijs SPJ, van Erkel AR, Dijkstra SPD (2010) A clinical comparative study on low versus medium viscosity polymethylmetacrylate bone cement in percutaneous vertebroplasty. Spine 35(20):E1037–1044PubMedCrossRef
27.
Zurück zum Zitat Chen WC, Tsai SHL, Goyal A, Fu T‑S, Lin T‑Y, Bydon M (2021) Comparison between vertebroplasty with high or low viscosity cement augmentation or kyphoplasty in cement leakage rate for patients with vertebral compression fracture: a systematic review and network meta-analysis. Eur Spine J 30(9):2680–2690PubMedCrossRef Chen WC, Tsai SHL, Goyal A, Fu T‑S, Lin T‑Y, Bydon M (2021) Comparison between vertebroplasty with high or low viscosity cement augmentation or kyphoplasty in cement leakage rate for patients with vertebral compression fracture: a systematic review and network meta-analysis. Eur Spine J 30(9):2680–2690PubMedCrossRef
28.
Zurück zum Zitat Greene DL, Isaac R, Neuwirth M, Bitan FD (2007) The eggshell technique for prevention of cement leakage during kyphoplasty. J Spinal Disord Tech 20(3):229–232PubMedCrossRef Greene DL, Isaac R, Neuwirth M, Bitan FD (2007) The eggshell technique for prevention of cement leakage during kyphoplasty. J Spinal Disord Tech 20(3):229–232PubMedCrossRef
29.
Zurück zum Zitat Hoppe S, Elfiky T, Keel MJB, Aghayev E, Ecker TM, Benneker LM (2016) Lavage prior to vertebral augmentation reduces the risk for cement leakage. Eur Spine J 25(11):3463–3469PubMedCrossRef Hoppe S, Elfiky T, Keel MJB, Aghayev E, Ecker TM, Benneker LM (2016) Lavage prior to vertebral augmentation reduces the risk for cement leakage. Eur Spine J 25(11):3463–3469PubMedCrossRef
30.
Zurück zum Zitat Groen RJM, du Toit DF, Phillips FM, Hoogland PVJM, Kuizenga K, Coppes MH et al (2004) Anatomical and pathological considerations in percutaneous vertebroplasty and kyphoplasty: a reappraisal of the vertebral venous system. Spine 29(13):1465–1471PubMedCrossRef Groen RJM, du Toit DF, Phillips FM, Hoogland PVJM, Kuizenga K, Coppes MH et al (2004) Anatomical and pathological considerations in percutaneous vertebroplasty and kyphoplasty: a reappraisal of the vertebral venous system. Spine 29(13):1465–1471PubMedCrossRef
31.
Zurück zum Zitat McCall T, Cole C, Dailey A (2008) Vertebroplasty and kyphoplasty: a comparative review of efficacy and adverse events. Curr Rev Musculoskelet Med 1(1):17–23PubMedPubMedCentralCrossRef McCall T, Cole C, Dailey A (2008) Vertebroplasty and kyphoplasty: a comparative review of efficacy and adverse events. Curr Rev Musculoskelet Med 1(1):17–23PubMedPubMedCentralCrossRef
32.
Zurück zum Zitat Mudano AS, Bian J, Cope JU, Curtis JR, Gross TP, Allison JJ et al (2008) Vertebroplasty and kyphoplasty are associated with an increased risk of secondary vertebral compression fractures: a population-based cohort study. Osteoporos Int 20(5):819–826PubMedPubMedCentralCrossRef Mudano AS, Bian J, Cope JU, Curtis JR, Gross TP, Allison JJ et al (2008) Vertebroplasty and kyphoplasty are associated with an increased risk of secondary vertebral compression fractures: a population-based cohort study. Osteoporos Int 20(5):819–826PubMedPubMedCentralCrossRef
33.
Zurück zum Zitat Song D, Meng B, Gan M, Niu J, Li S, Chen H et al (2014) The incidence of secondary vertebral fracture of vertebral augmentation techniques versus conservative treatment for painful osteoporotic vertebral fractures: a systematic review and meta-analysis. Acta Radiol 56(8):970–979PubMedCrossRef Song D, Meng B, Gan M, Niu J, Li S, Chen H et al (2014) The incidence of secondary vertebral fracture of vertebral augmentation techniques versus conservative treatment for painful osteoporotic vertebral fractures: a systematic review and meta-analysis. Acta Radiol 56(8):970–979PubMedCrossRef
34.
Zurück zum Zitat Silverman SL (1992) The clinical consequences of vertebral compression fracture. Bone 13:S27–31PubMedCrossRef Silverman SL (1992) The clinical consequences of vertebral compression fracture. Bone 13:S27–31PubMedCrossRef
36.
Zurück zum Zitat Trout AT, Kallmes DF, Kaufmann TJ (2006) New fractures after vertebroplasty: adjacent fractures occur significantly sooner. AJNR Am J Neuroradiol 27(1):217–223PubMedPubMedCentral Trout AT, Kallmes DF, Kaufmann TJ (2006) New fractures after vertebroplasty: adjacent fractures occur significantly sooner. AJNR Am J Neuroradiol 27(1):217–223PubMedPubMedCentral
37.
Zurück zum Zitat Chen W‑J, Kao Y‑H, Yang S‑C, Yu S‑W, Tu Y‑K, Chung K‑C (2010) Impact of cement leakage into disks on the development of adjacent vertebral compression fractures. J Spinal Disord Tech 23(1):35–39PubMedCrossRef Chen W‑J, Kao Y‑H, Yang S‑C, Yu S‑W, Tu Y‑K, Chung K‑C (2010) Impact of cement leakage into disks on the development of adjacent vertebral compression fractures. J Spinal Disord Tech 23(1):35–39PubMedCrossRef
38.
Zurück zum Zitat Lin EP, Ekholm S, Hiwatashi A, Westesson P‑L (2004) Vertebroplasty: cement leakage into the disc increases the risk of new fracture of adjacent vertebral body. AJNR Am J Neuroradiol 25(2):175–180PubMedPubMedCentral Lin EP, Ekholm S, Hiwatashi A, Westesson P‑L (2004) Vertebroplasty: cement leakage into the disc increases the risk of new fracture of adjacent vertebral body. AJNR Am J Neuroradiol 25(2):175–180PubMedPubMedCentral
39.
Zurück zum Zitat Buchbinder R, Osborne RH, Ebeling PR, Wark JD, Mitchell P, Wriedt C et al (2009) A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med 361(6):557–568PubMedCrossRef Buchbinder R, Osborne RH, Ebeling PR, Wark JD, Mitchell P, Wriedt C et al (2009) A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med 361(6):557–568PubMedCrossRef
40.
Zurück zum Zitat Kallmes DF, Comstock BA, Heagerty PJ, Turner JA, Wilson DJ, Diamond TH et al (2009) A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med 361(6):569–579PubMedPubMedCentralCrossRef Kallmes DF, Comstock BA, Heagerty PJ, Turner JA, Wilson DJ, Diamond TH et al (2009) A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med 361(6):569–579PubMedPubMedCentralCrossRef
41.
Zurück zum Zitat Aebi M (2009) Vertebroplasty: about sense and nonsense of uncontrolled “controlled randomized prospective trials.”. Eur Spine J 18(9):1247–1248PubMedPubMedCentralCrossRef Aebi M (2009) Vertebroplasty: about sense and nonsense of uncontrolled “controlled randomized prospective trials.”. Eur Spine J 18(9):1247–1248PubMedPubMedCentralCrossRef
42.
Zurück zum Zitat Kroon F, Staples M, Ebeling PR, Wark JD, Osborne RH, Mitchell PJ et al (2014) Two-year results of a randomized placebo-controlled trial of vertebroplasty for acute osteoporotic vertebral fractures. J Bone Miner Res 29(6):1346–1355PubMedCrossRef Kroon F, Staples M, Ebeling PR, Wark JD, Osborne RH, Mitchell PJ et al (2014) Two-year results of a randomized placebo-controlled trial of vertebroplasty for acute osteoporotic vertebral fractures. J Bone Miner Res 29(6):1346–1355PubMedCrossRef
43.
Zurück zum Zitat Firanescu CE, de Vries J, Lodder P, Venmans A, Schoemaker MC, Smeet AJ et al (2018) Vertebroplasty versus sham procedure for painful acute osteoporotic vertebral compression fractures (VERTOS IV): randomised sham controlled clinical trial. BMJ 361:k1551PubMedPubMedCentralCrossRef Firanescu CE, de Vries J, Lodder P, Venmans A, Schoemaker MC, Smeet AJ et al (2018) Vertebroplasty versus sham procedure for painful acute osteoporotic vertebral compression fractures (VERTOS IV): randomised sham controlled clinical trial. BMJ 361:k1551PubMedPubMedCentralCrossRef
44.
Zurück zum Zitat Luo W, Cui C, Pourtaheri S, Garfin S (2018) Efficacy of vertebral augmentation for vertebral compression fractures: a review of meta-analyses. Spine Surg Relat Res 2(3):163–168PubMedPubMedCentralCrossRef Luo W, Cui C, Pourtaheri S, Garfin S (2018) Efficacy of vertebral augmentation for vertebral compression fractures: a review of meta-analyses. Spine Surg Relat Res 2(3):163–168PubMedPubMedCentralCrossRef
45.
Zurück zum Zitat Yuan W‑H, Hsu H‑C, Lai K‑L (2016) Vertebroplasty and balloon kyphoplasty versus conservative treatment for osteoporotic vertebral compression fractures. Medicine 95(31):e4491PubMedPubMedCentralCrossRef Yuan W‑H, Hsu H‑C, Lai K‑L (2016) Vertebroplasty and balloon kyphoplasty versus conservative treatment for osteoporotic vertebral compression fractures. Medicine 95(31):e4491PubMedPubMedCentralCrossRef
46.
Zurück zum Zitat Li L, Ren J, Liu J, Wang H, Wang X, Liu Z et al (2015) Results of vertebral augmentation treatment for patients of painful osteoporotic vertebral compression fractures: a meta-analysis of eight randomized controlled trials. PLoS ONE 10(9):e138126PubMedPubMedCentralCrossRef Li L, Ren J, Liu J, Wang H, Wang X, Liu Z et al (2015) Results of vertebral augmentation treatment for patients of painful osteoporotic vertebral compression fractures: a meta-analysis of eight randomized controlled trials. PLoS ONE 10(9):e138126PubMedPubMedCentralCrossRef
47.
Zurück zum Zitat Chen D, An Z‑Q, Song S, Tang J‑F, Qin H (2014) Percutaneous vertebroplasty compared with conservative treatment in patients with chronic painful osteoporotic spinal fractures. J Clin Neurosci 21(3):473–477PubMedCrossRef Chen D, An Z‑Q, Song S, Tang J‑F, Qin H (2014) Percutaneous vertebroplasty compared with conservative treatment in patients with chronic painful osteoporotic spinal fractures. J Clin Neurosci 21(3):473–477PubMedCrossRef
48.
Zurück zum Zitat Liu J, Li X, Tang D, Cui X, Li X, Yao M et al (2013) Comparing pain reduction following vertebroplasty and conservative treatment for osteoporotic vertebral compression fractures: a meta-analysis of randomized controlled trials. Pain Physician 16(5):455–464PubMed Liu J, Li X, Tang D, Cui X, Li X, Yao M et al (2013) Comparing pain reduction following vertebroplasty and conservative treatment for osteoporotic vertebral compression fractures: a meta-analysis of randomized controlled trials. Pain Physician 16(5):455–464PubMed
49.
Zurück zum Zitat Anderson PA, Froyshteter AB, Tontz WL (2013) Meta-analysis of vertebral augmentation compared with conservative treatment for osteoporotic spinal fractures. J Bone Miner Res 28(2):372–382PubMedCrossRef Anderson PA, Froyshteter AB, Tontz WL (2013) Meta-analysis of vertebral augmentation compared with conservative treatment for osteoporotic spinal fractures. J Bone Miner Res 28(2):372–382PubMedCrossRef
50.
Zurück zum Zitat Shi M, Cai X, Lin T, Wang W, Yan S (2012) Is there really no benefit of vertebroplasty for osteoporotic vertebral fractures? A meta-analysis. Clin Orthop Relat Res 470(10):2785–2799PubMedPubMedCentralCrossRef Shi M, Cai X, Lin T, Wang W, Yan S (2012) Is there really no benefit of vertebroplasty for osteoporotic vertebral fractures? A meta-analysis. Clin Orthop Relat Res 470(10):2785–2799PubMedPubMedCentralCrossRef
51.
Zurück zum Zitat Clark W, Bird P, Gonski P, Diamond TH, Smerdely P, McNeil HP et al (2016) Safety and efficacy of vertebroplasty for acute painful osteoporotic fractures (VAPOUR): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet 388(10052):1408–1416PubMedCrossRef Clark W, Bird P, Gonski P, Diamond TH, Smerdely P, McNeil HP et al (2016) Safety and efficacy of vertebroplasty for acute painful osteoporotic fractures (VAPOUR): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet 388(10052):1408–1416PubMedCrossRef
52.
Zurück zum Zitat Wardlaw D, Cummings SR, Meirhaeghe JV, Bastian L, Tillman JB, Ranstam J et al (2009) Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): a randomised controlled trial. Lancet 373(9668):1016–1024PubMedCrossRef Wardlaw D, Cummings SR, Meirhaeghe JV, Bastian L, Tillman JB, Ranstam J et al (2009) Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): a randomised controlled trial. Lancet 373(9668):1016–1024PubMedCrossRef
53.
Zurück zum Zitat Vaccaro AR, Oner C, Kepler CK, Dvorak M, Schnake K, Bellabarba C et al (2013) AOSpine thoracolumbar spine injury classification system: fracture description, neurological status, and key modifiers. Spine 38(23):2028–2037PubMedCrossRef Vaccaro AR, Oner C, Kepler CK, Dvorak M, Schnake K, Bellabarba C et al (2013) AOSpine thoracolumbar spine injury classification system: fracture description, neurological status, and key modifiers. Spine 38(23):2028–2037PubMedCrossRef
54.
Zurück zum Zitat Becker S, Chavanne A, Spitaler R, Kropik K, Aigner N, Ogon M et al (2008) Assessment of different screw augmentation techniques and screw designs in osteoporotic spines. Eur Spine J 17(11):1462–1469PubMedPubMedCentralCrossRef Becker S, Chavanne A, Spitaler R, Kropik K, Aigner N, Ogon M et al (2008) Assessment of different screw augmentation techniques and screw designs in osteoporotic spines. Eur Spine J 17(11):1462–1469PubMedPubMedCentralCrossRef
55.
Zurück zum Zitat Zindrick MR, Wiltse LL, Widell EH, Thomas JC, Holland WR, Field BT et al (1986) A biomechanical study of intrapeduncular screw fixation in the lumbosacral spine. Clin Orthop Relat Res 203(203):99–112 Zindrick MR, Wiltse LL, Widell EH, Thomas JC, Holland WR, Field BT et al (1986) A biomechanical study of intrapeduncular screw fixation in the lumbosacral spine. Clin Orthop Relat Res 203(203):99–112
56.
Zurück zum Zitat Wittenberg RH, Shea M, Swartz DE, Lee KS, White AA, Hayes WC (1991) Importance of bone mineral density in instrumented spine fusions. Spine 16(6):647–652PubMedCrossRef Wittenberg RH, Shea M, Swartz DE, Lee KS, White AA, Hayes WC (1991) Importance of bone mineral density in instrumented spine fusions. Spine 16(6):647–652PubMedCrossRef
57.
Zurück zum Zitat Wuisman PIJM, Dijk MV, Staal H, Royen BJV (2000) Augmentation of (pedicle) screws with calcium apatite cement in patients with severe progressive osteoporotic spinal deformities: an innovative technique. Eur Spine J 9(6):528–533PubMedPubMedCentralCrossRef Wuisman PIJM, Dijk MV, Staal H, Royen BJV (2000) Augmentation of (pedicle) screws with calcium apatite cement in patients with severe progressive osteoporotic spinal deformities: an innovative technique. Eur Spine J 9(6):528–533PubMedPubMedCentralCrossRef
58.
Zurück zum Zitat Elder BD, S‑FL L, Holmes C, Goodwin CR, Kosztowski TA, Lina IA et al (2015) The biomechanics of pedicle screw augmentation with cement. Spine J 15(6):1432–1445PubMedCrossRef Elder BD, S‑FL L, Holmes C, Goodwin CR, Kosztowski TA, Lina IA et al (2015) The biomechanics of pedicle screw augmentation with cement. Spine J 15(6):1432–1445PubMedCrossRef
59.
Zurück zum Zitat Sarzier JS, Evans AJ, Cahill DW (2002) Increased pedicle screw pullout strength with vertebroplasty augmentation in osteoporotic spines. J Neurosurg Spine 96(3):309–312CrossRef Sarzier JS, Evans AJ, Cahill DW (2002) Increased pedicle screw pullout strength with vertebroplasty augmentation in osteoporotic spines. J Neurosurg Spine 96(3):309–312CrossRef
60.
Zurück zum Zitat Tan Q, Wu J, Peng F, Zang Y, Li Y, Zhao X et al (2016) Augmented PMMA distribution: improvement of mechanical property and reduction of leakage rate of a fenestrated pedicle screw with diameter-tapered perforations. J Neurosurg Spine 24(6):971–977PubMedCrossRef Tan Q, Wu J, Peng F, Zang Y, Li Y, Zhao X et al (2016) Augmented PMMA distribution: improvement of mechanical property and reduction of leakage rate of a fenestrated pedicle screw with diameter-tapered perforations. J Neurosurg Spine 24(6):971–977PubMedCrossRef
61.
Zurück zum Zitat Schulze M, Riesenbeck O, Vordemvenne T, Raschke MJ, Evers J, Hartensuer R et al (2020) Complex biomechanical properties of non-augmented and augmented pedicle screws in human vertebrae with reduced bone density. BMC Musculoskelet Disord 21(1):151PubMedPubMedCentralCrossRef Schulze M, Riesenbeck O, Vordemvenne T, Raschke MJ, Evers J, Hartensuer R et al (2020) Complex biomechanical properties of non-augmented and augmented pedicle screws in human vertebrae with reduced bone density. BMC Musculoskelet Disord 21(1):151PubMedPubMedCentralCrossRef
62.
Zurück zum Zitat Frankel BM, D’Agostino S, Wang C (2007) A biomechanical cadaveric analysis of polymethylmethacrylate-augmented pedicle screw fixation. J Neurosurg Spine 7(1):47–53PubMedCrossRef Frankel BM, D’Agostino S, Wang C (2007) A biomechanical cadaveric analysis of polymethylmethacrylate-augmented pedicle screw fixation. J Neurosurg Spine 7(1):47–53PubMedCrossRef
63.
Zurück zum Zitat Liu D, Zhang B, Xie Q, Kang X, Zhou J, Wang C et al (2016) Biomechanical comparison of pedicle screw augmented with different volumes of polymethylmethacrylate in osteoporotic and severely osteoporotic cadaveric lumbar vertebrae: an experimental study. Spine J 16(9):1124–1132PubMedCrossRef Liu D, Zhang B, Xie Q, Kang X, Zhou J, Wang C et al (2016) Biomechanical comparison of pedicle screw augmented with different volumes of polymethylmethacrylate in osteoporotic and severely osteoporotic cadaveric lumbar vertebrae: an experimental study. Spine J 16(9):1124–1132PubMedCrossRef
64.
Zurück zum Zitat Paré PE, Chappuis JL, Rampersaud R, Agarwala AO, Perra JH, Erkan S et al (2011) Biomechanical evaluation of a novel fenestrated pedicle screw augmented with bone cement in osteoporotic spines. Spine 36(18):E1210–1214PubMedCrossRef Paré PE, Chappuis JL, Rampersaud R, Agarwala AO, Perra JH, Erkan S et al (2011) Biomechanical evaluation of a novel fenestrated pedicle screw augmented with bone cement in osteoporotic spines. Spine 36(18):E1210–1214PubMedCrossRef
65.
Zurück zum Zitat Bostelmann R, Keiler A, Steiger HJ, Scholz A, Cornelius JF, Schmoelz W (2017) Effect of augmentation techniques on the failure of pedicle screws under cranio-caudal cyclic loading. Eur Spine J 26(1):181–188PubMedCrossRef Bostelmann R, Keiler A, Steiger HJ, Scholz A, Cornelius JF, Schmoelz W (2017) Effect of augmentation techniques on the failure of pedicle screws under cranio-caudal cyclic loading. Eur Spine J 26(1):181–188PubMedCrossRef
66.
Zurück zum Zitat Tang Y, Guo H, Guo D, Luo P, Li Y, Mo G et al (2020) Effect and potential risks of using multilevel cement-augmented pedicle screw fixation in osteoporotic spine with lumbar degenerative disease. BMC Musculoskelet Disord 21(1):274PubMedPubMedCentralCrossRef Tang Y, Guo H, Guo D, Luo P, Li Y, Mo G et al (2020) Effect and potential risks of using multilevel cement-augmented pedicle screw fixation in osteoporotic spine with lumbar degenerative disease. BMC Musculoskelet Disord 21(1):274PubMedPubMedCentralCrossRef
67.
Zurück zum Zitat Seo JH, Ju CI, Kim SW, Kim JK, Shin H (2012) Clinical efficacy of bone cement augmented screw fixation for the severe osteoporotic spine. Korean J Spine 9(2):79–84PubMedPubMedCentralCrossRef Seo JH, Ju CI, Kim SW, Kim JK, Shin H (2012) Clinical efficacy of bone cement augmented screw fixation for the severe osteoporotic spine. Korean J Spine 9(2):79–84PubMedPubMedCentralCrossRef
68.
Zurück zum Zitat Saman AE, Meier S, Sander A, Kelm A, Marzi I, Laurer H (2013) Reduced loosening rate and loss of correction following posterior stabilization with or without PMMA augmentation of pedicle screws in vertebral fractures in the elderly. Eur J Trauma Emerg Surg 39(5):455–460PubMedCrossRef Saman AE, Meier S, Sander A, Kelm A, Marzi I, Laurer H (2013) Reduced loosening rate and loss of correction following posterior stabilization with or without PMMA augmentation of pedicle screws in vertebral fractures in the elderly. Eur J Trauma Emerg Surg 39(5):455–460PubMedCrossRef
69.
Zurück zum Zitat Rometsch E, Spruit M, Zigler JE, Menon VK, Ouellet JA, Mazel C et al (2020) Screw-related complications after instrumentation of the osteoporotic spine: a systematic literature review with meta-analysis. Global Spine J 10(1):69–88PubMedCrossRef Rometsch E, Spruit M, Zigler JE, Menon VK, Ouellet JA, Mazel C et al (2020) Screw-related complications after instrumentation of the osteoporotic spine: a systematic literature review with meta-analysis. Global Spine J 10(1):69–88PubMedCrossRef
70.
Zurück zum Zitat Bullmann V, Schmoelz W, Richter M, Grathwohl C, Schulte TL (2010) Revision of cannulated and perforated cement-augmented pedicle screws: a biomechanical study in human cadavers. Spine 35(19):E932–939PubMedCrossRef Bullmann V, Schmoelz W, Richter M, Grathwohl C, Schulte TL (2010) Revision of cannulated and perforated cement-augmented pedicle screws: a biomechanical study in human cadavers. Spine 35(19):E932–939PubMedCrossRef
71.
Zurück zum Zitat Blattert TR, Glasmacher S, Riesner H‑J, Josten C (2009) Revision characteristics of cement-augmented, cannulatedfenestrated pedicle screws in the osteoporotic vertebral body: a biomechanical in vitro investigation: technical note. J Neurosurg Spine 11(1):23–27PubMedCrossRef Blattert TR, Glasmacher S, Riesner H‑J, Josten C (2009) Revision characteristics of cement-augmented, cannulatedfenestrated pedicle screws in the osteoporotic vertebral body: a biomechanical in vitro investigation: technical note. J Neurosurg Spine 11(1):23–27PubMedCrossRef
72.
Zurück zum Zitat Mueller JU, Baldauf J, Marx S, Kirsch M, Schroeder HWS, Pillich DT (2016) Cement leakage in pedicle screw augmentation: a prospective analysis of 98 patients and 474 augmented pedicle screws. J Neurosurg Spine 25(1):103–109PubMedCrossRef Mueller JU, Baldauf J, Marx S, Kirsch M, Schroeder HWS, Pillich DT (2016) Cement leakage in pedicle screw augmentation: a prospective analysis of 98 patients and 474 augmented pedicle screws. J Neurosurg Spine 25(1):103–109PubMedCrossRef
73.
Zurück zum Zitat Guo H, Tang Y, Guo D, Zhang S, Li Y, Mo G et al (2019) The cement leakage in cement-augmented pedicle screw instrumentation in degenerative lumbosacral diseases: a retrospective analysis of 202 cases and 950 augmented pedicle screws. Eur Spine J 28(7):1661–1669PubMedCrossRef Guo H, Tang Y, Guo D, Zhang S, Li Y, Mo G et al (2019) The cement leakage in cement-augmented pedicle screw instrumentation in degenerative lumbosacral diseases: a retrospective analysis of 202 cases and 950 augmented pedicle screws. Eur Spine J 28(7):1661–1669PubMedCrossRef
74.
Zurück zum Zitat Janssen I, Ryang Y‑M, Gempt J, Bette S, Gerhardt J, Kirschke JS et al (2017) Risk of cement leakage and pulmonary embolism by bone cement-augmented pedicle screw fixation of the thoracolumbar spine. Spine J 17(6):837–844PubMedCrossRef Janssen I, Ryang Y‑M, Gempt J, Bette S, Gerhardt J, Kirschke JS et al (2017) Risk of cement leakage and pulmonary embolism by bone cement-augmented pedicle screw fixation of the thoracolumbar spine. Spine J 17(6):837–844PubMedCrossRef
75.
Zurück zum Zitat Hu M‑H, Wu HTH, Chang M‑C, Yu W‑K, Wang S‑T, Liu C‑L (2011) Polymethylmethacrylate augmentation of the pedicle screw: the cement distribution in the vertebral body. Eur Spine J 20(8):1281PubMedPubMedCentralCrossRef Hu M‑H, Wu HTH, Chang M‑C, Yu W‑K, Wang S‑T, Liu C‑L (2011) Polymethylmethacrylate augmentation of the pedicle screw: the cement distribution in the vertebral body. Eur Spine J 20(8):1281PubMedPubMedCentralCrossRef
Metadaten
Titel
Zementaugmentation in der Wirbelsäulenchirurgie
verfasst von
Dr. med. Philipp Schleicher
Alexander Wengert
Jonathan Neuhoff
Frank Kandziora
Publikationsdatum
23.05.2022
Verlag
Springer Medizin
Erschienen in
Die Unfallchirurgie / Ausgabe 6/2022
Print ISSN: 2731-7021
Elektronische ISSN: 2731-703X
DOI
https://doi.org/10.1007/s00113-022-01188-7

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