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14.09.2023 | IgG4-assoziierte Erkrankungen | Übersichten

Speicheldrüsenschwellung und Sicca-Symptomatik bei Morbus Kimura, einer seltenen rheumatologischen Differenzialdiagnose mit wegweisend hohem IgE-Serumspiegel – eine aktuelle Übersicht nach Literatursuche

verfasst von: Prof. Jürgen Braun, Kirsten Karberg

Erschienen in: Zeitschrift für Rheumatologie

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Zusammenfassung

Rheumatische Erkrankungen des Bewegungsapparats umfassen verschiedene Erkrankungen mit zum Teil sehr unterschiedlichen Symptomen, von denen einige lokal begrenzt sind und andere systemische Merkmale aufweisen. Autoimmunphänomene wie z. B. beim Sjögren-Syndrom verursachen oft Symptome wie Xerostomie und Xerophthalmie im Zusammenhang mit Entzündungen in den Speicheldrüsen. Die Pathogenese dieser Erkrankungen ist nur zum Teil geklärt. Ähnlich verhält es sich mit allergischen Erkrankungen, die sich bezüglich der Symptome und Pathomechanismen sonst deutlich unterscheiden, aber auch hier können selten Schwellungen der Speicheldrüsen auftreten. Da es sich um eine mögliche Differenzialdiagnose des Sjögren-Syndroms oder auch von IgG4-assoziierten Erkrankungen handelt und ein solcher Fall kürzlich beschrieben wurde, wurde eine Literatursuche in PubMed gemacht, deren Ergebnisse hier präsentiert und in einer kurzen Übersicht im Folgenden zusammengestellt werden.
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Metadaten
Titel
Speicheldrüsenschwellung und Sicca-Symptomatik bei Morbus Kimura, einer seltenen rheumatologischen Differenzialdiagnose mit wegweisend hohem IgE-Serumspiegel – eine aktuelle Übersicht nach Literatursuche
verfasst von
Prof. Jürgen Braun
Kirsten Karberg
Publikationsdatum
14.09.2023
Verlag
Springer Medizin
Erschienen in
Zeitschrift für Rheumatologie
Print ISSN: 0340-1855
Elektronische ISSN: 1435-1250
DOI
https://doi.org/10.1007/s00393-023-01411-9

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Perioperative Checkpointhemmer-Therapie verbessert NSCLC-Prognose

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Eine perioperative Therapie mit Nivolumab reduziert das Risiko für Rezidive und Todesfälle bei operablem NSCLC im Vergleich zu einer alleinigen neoadjuvanten Chemotherapie um über 40%. Darauf deuten die Resultate der Phase-3-Studie CheckMate 77T.

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