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Current Dermatology Reports

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12.12.2023 | REVIEW

Mpox: Diagnosis and Management for the Inpatient Dermatologist

verfasst von: Alexis G. Strahan, Sigrid Collier, John Trinidad, Joanna Harp, Esther E. Freeman

Erschienen in: Current Dermatology Reports | Ausgabe 4/2023

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Abstract

Purpose of Review

Mpox, though largely a self-limited disease, may have severe manifestations requiring hospitalization, particularly in immunocompromised individuals. This review highlights the history and epidemiology, clinical course, diagnostic pearls, and management of mpox in the context of inpatient dermatology.

Recent Findings

The 2022 outbreak had unique features in comparison to previous outbreaks and endemic mpox, including a predominance of anogenital lesions and an atypical progression of lesion morphologies. The frequency of concurrent STIs is as high as 76%- necessitating co-testing for HIV and other STIs. Intradermal administration of the live, nonreplicating vaccine (Jynneos) requires 1/5^th of the standard dose, shows similar immunogenicity, and provides increased vaccination reach.

Summary

Mpox may require hospitalization in cases of severe disease, uncontrolled pain, or with other cutaneous complications. The inpatient dermatologist plays an important role diagnosis of mpox and should recognize the variability in morphologic presentation and need for STI and HIV co-testing.

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Titel: Mpox: Diagnosis and Management for the Inpatient Dermatologist
verfasst von: Alexis G. Strahan
Sigrid Collier
John Trinidad
Joanna Harp
Esther E. Freeman
Publikationsdatum: 12.12.2023
Verlag: Springer US
Erschienen in: Current Dermatology Reports / Ausgabe 4/2023
Elektronische ISSN: 2162-4933
DOI: https://doi.org/10.1007/s13671-023-00411-x

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