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Critical Care
Erschienen in: Critical Care 3/2012

01.06.2012 | Review

Bench-to-bedside review: Rapid molecular diagnostics for bloodstream infection - a new frontier?

verfasst von: Arash Afshari, Jacques Schrenzel, Margareta Ieven, Stephan Harbarth

Erschienen in: Critical Care | Ausgabe 3/2012

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Abstract

Among critically ill patients, the diagnosis of bloodstream infection poses a major challenge. Current standard bacterial identification based on blood culture platforms is intrinsically time-consuming and slow. The continuous evolvement of molecular techniques has the potential of providing a faster, more sensitive and direct identification of causative pathogens without prior need for cultivation. This may ultimately impact clinical decision-making and antimicrobial treatment. This review summarises the currently available technologies, their strengths and limitations and the obstacles that have to be overcome in order to develop a satisfactory bedside point-of-care diagnostic tool for detection of bloodstream infection.
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Metadaten
Titel
Bench-to-bedside review: Rapid molecular diagnostics for bloodstream infection - a new frontier?
verfasst von
Arash Afshari
Jacques Schrenzel
Margareta Ieven
Stephan Harbarth
Publikationsdatum
01.06.2012
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe 3/2012
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc11202

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