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13.07.2022 | Original Article

Capsaicin supplementation did not increase skeletal muscle oxygen saturation and muscular endurance during resistance exercise: a randomized and crossover study

verfasst von: Mônica Volino-Souza, Gustavo Vieira de Oliveira, Iana Hercules de Carvalho, Carlos Adam Conte-Junior, Thiago da Silveira Alvares

Erschienen in: Sport Sciences for Health | Ausgabe 3/2023

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Abstract

Purpose

Capsaicin (CAP) has been demonstrated to activate the transient receptor potential cation channel subfamily V member 1 (TRPV1), which can regulate nitric oxide production and, consequently, affect oxygen delivery to the muscles. In addition, TRPV1 activation can lead to calcium release from the sarcoplasmic reticulum, which is crucial for optimal force development. Therefore, this study aimed to evaluate the effect of a single dose of capsaicin on leg extension exercise performance and skeletal muscle oxygenation (SmO2) during exercise and exercise recovery in physically active individuals.

Methods

In a randomized, double-blind, crossover study, eight males ingested 12 mg of CAP or maltodextrin as a placebo (PLA). Forty-five minutes after supplementation, the participants performed three sets of leg extension exercises at 70% of 1 repetition maximum, and the number of repetitions was evaluated. During exercise and exercise recovery, SmO₂ parameters were recorded. Plasma lactate was analyzed before supplementation, immediately, and 10 min after exercise.

Results

There were no changes in SmO₂ parameters (p > 0.05) and the number of repetitions (p > 0.05) throughout the three sets of leg extensions. Additionally, a medium (d = 0.67), large (d = 0.83) and small (d = 0.31) effect size was observed in resaturation rate during set 1, set 2, and set 3 recovery. Plasma lactate increased significantly (p < 0.05) immediately after exercise in both CAP and PLA groups without significant changes between the groups (p > 0.05).

Conclusion

A single dose of capsaicin did not change SmO₂ parameters and muscular performance during resistance exercise in physically active individuals.

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Titel: Capsaicin supplementation did not increase skeletal muscle oxygen saturation and muscular endurance during resistance exercise: a randomized and crossover study
verfasst von: Mônica Volino-Souza
Gustavo Vieira de Oliveira
Iana Hercules de Carvalho
Carlos Adam Conte-Junior
Thiago da Silveira Alvares
Publikationsdatum: 13.07.2022
Verlag: Springer Milan
Erschienen in: Sport Sciences for Health / Ausgabe 3/2023
Print ISSN: 1824-7490
Elektronische ISSN: 1825-1234
DOI: https://doi.org/10.1007/s11332-022-00982-5

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Capsaicin supplementation did not increase skeletal muscle oxygen saturation and muscular endurance during resistance exercise: a randomized and crossover study