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Medizinische Klinik - Intensivmedizin und Notfallmedizin

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01.12.2023 | Introduction to the topic

Challenges in combating sepsis in Germany—Learning from others and the COVID-19 pandemic

verfasst von: Prof. Dr. Konrad Reinhart, ML, Stefan Kluge, Tobias Welte

Erschienen in: Medizinische Klinik - Intensivmedizin und Notfallmedizin | Sonderheft 2/2023

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Sir William Osler, one of the most influential and beloved physicians of all time, pointed out in 1898: “Humanity has but three great enemies: fever, famine, and war; of these the greatest, by far the most terrible, is fever.” For most parts of the world, where over 80% of mankind live, this still holds true. …

Rudd KE, Johnson SC, Agesa KM et al (2020) Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the global burden of disease study. Lancet 395(10219):200–211CrossRefPubMedPubMedCentral

van den Berghe M, van Beuningen FE, Ter Maaten JC et al (2022) Hospital-related costs of sepsis around the world: A systematic review exploring the economic burden of sepsis. J Crit Care 71:154096. https://doi.org/10.1016/j.jcrc.2022.154096 (Epub 2022 Jul 12. PMID: 35839604)CrossRef

GBD 2019 Antimicrobial Resistance Collaborators (2022) Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 400(10369):2221–2248. https://doi.org/10.1016/S0140-6736(22)02185-7 (Epub 2022 Nov 21. PMID: 36423648; PMCID: PMC9763654)CrossRef

Improving the prevention, diagnosis and clinical management of sepsis, Seventieth World Health Assembly (WHA70.7), Agenda item 12.2, 29. https://apps.who.int/gb/ebwha/pdf_files/WHA70/A70_13-en.pdf (May 2017)

Shappell C, Rhee C, Klompas M (2023) Update on Sepsis Epidemiology in the Era of COVID-19. Semin Respir Crit Care Med 44(1):173–184. https://doi.org/10.1055/s-0042-1759880 (2023 Jan 16. PMID: 36646093)CrossRefPubMed

(2022) 14.9 million excess deaths associated with the COVID-19 pandemic in 2020 and 2021. https://www.who.int/news/item/05-05-2022-14.9-million-excess-deaths-were-associated-with-the-covid-19-pandemic-in-2020-and-2021. Accessed 19 Aug 2023

Schwarzkopf D, Rose N, Fleischmann-Struzek C et al (2023) Understanding the biases to sepsis surveillance and quality assurance caused by inaccurate coding in administrative health data. Infection. https://doi.org/10.1007/s15010-023-02091-yCrossRefPubMed

Mellhammar L, Wollter E, Dahlberg J et al (2023) JAMA: Estimating Sepsis Incidence Using Administrative Data and Clinical Medical Record Review. Netw Open 6(8):e2331168. https://doi.org/10.1001/jamanetworkopen.2023.31168 (Aug 1)CrossRef

Rhee C, Dantes R, Epstein L et al (2017) Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009–2014. JAMA 318:1241–1249CrossRefPubMedPubMedCentral

10.

Fleischmann-Struzek C, Mikolajetz A, Schwarzkopf D et al (2018) Challenges in Assessing the Burden of Sepsis and Understanding the Inequalities of Sepsis Outcomes between National Health Systems—Secular Trends in Sepsis and Infection Incidence and Mortality in Germany. Intensive Care Med 44:1826–1835. https://doi.org/10.1007/s00134-018-5377-4CrossRefPubMedPubMedCentral

11.

Kaukonen KM, Bailey M, Suzuki S, Pilcher D, Bellomo R (2014) Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000–2012. JAMA 311:1308–1316CrossRefPubMed

12.

Shankar-Hari M, Harrison DA, Rowan KM (2016) Differences in impact of definitional elements on mortality precludes international comparisons of sepsis epidemiology—a cohort study illustrating the need for standardized reporting. Crit Care Med 44(12):2223–2230CrossRefPubMed

13.

Bloos F, Rüddel H, Thomas-Rüddel D et al (2017) Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial. Intensive Care Med 43:1602–1612. https://doi.org/10.1007/s00134-017-4782-4CrossRefPubMed

14.

Matthaeus-Kraemer CT, Thomas-Rueddel DO, Schwarzkopf D et al (2015) Barriers and supportive conditions to improve quality of care for critically ill patients: a team approach to quality improvement. J Crit Care 30:685–691. https://doi.org/10.1016/j.jcrc.2015.03.022CrossRefPubMed

15.

Fleischmann-Struzek C, Rudd K, (2023) The Challenges of Assessing the Burden of Sepsis: Med Klin Intensivmed Notfmed. https://doi.org/10.1007/s00063-023-01088-7

16.

Prescott H, Ostermann M (2023) What is new and different in the 2021 Surviving Sepsis Campaign Guidelines: Med Klin Intensivmed Notfmed. https://doi.org/10.1007/s00063-023-01028-5

17.

Giamarellos-Bourboulis E (2023) Adjunctive Therapy in COVID-19 and Sepsis—What did we learn? Med Klin Intensivmed Notfmed. https://doi.org/10.1007/s00063-023-01089-6

18.

Guzzardella A, Motos A, Vallverdú J, Torres A (2023) Corticosteroids in sepsis and community-acquired pneumonia Med Klin Intensivmed Notfmed. https://doi.org/10.1007/s00063-023-01093-w

19.

(2023) Coronavirus (Covid-19)—Drugs. https://www.fda.gov/drugs/emergency-preparedness-drugs/coronavirus-covid-19-drugs. Accessed 12 Mar 2023

20.

Vlaar A, Witzenrath M, van Paassen P (2022) Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3. Lancet Respir Med 10(12):P1137–1146 (December)CrossRef

21.

Murakami N, Hayden R, Hills T et al (2023) Therapeutic advances in COVID-19. Nat Rev Nephrol 19:38–52. https://doi.org/10.1038/s41581-022-00642-4CrossRefPubMed

Titel: Challenges in combating sepsis in Germany—Learning from others and the COVID-19 pandemic
verfasst von: Prof. Dr. Konrad Reinhart, ML
Stefan Kluge
Tobias Welte
Publikationsdatum: 01.12.2023
Verlag: Springer Medizin
Erschienen in: Medizinische Klinik - Intensivmedizin und Notfallmedizin / Ausgabe Sonderheft 2/2023
Print ISSN: 2193-6218
Elektronische ISSN: 2193-6226
DOI: https://doi.org/10.1007/s00063-023-01100-0

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