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The Contribution of Roberto Montesano to the Study of Interactions Between Epithelial Sheets and the Surrounding Extracellular Matrix

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Abstract

The interactions between epithelial cells and the surrounding extracellular matrix (ECM) are a central issue in research on morphogenesis. Since the studies by Grobstein (1954), it has become increasingly clear that the ECM not only serves as an inert physical scaffolding for the developing tissues but also provides environmental signals to the cells involved, playing a guiding role in morphogenetic processes. Moreover, the ECM is the natural substratum through which various cell types migrate during embryogenesis.

Published in “International Journal of Developmental Biology”, 54:1–6, 2010

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Correspondence to Domenico Ribatti .

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Ribatti, D. (2010). The Contribution of Roberto Montesano to the Study of Interactions Between Epithelial Sheets and the Surrounding Extracellular Matrix. In: Protagonists of Medicine. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3741-1_13

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