Skip to main content
Erschienen in: Archives of Gynecology and Obstetrics 6/2013

01.06.2013 | Gynecologic Oncology

Chest wall resection and reconstruction for locally advanced primary breast cancer

verfasst von: Ursula Hille, Philipp Soergel, Patrick Zardo, Stefanie Pertschy, Kai Busch, Stefan Fischer

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 6/2013

Einloggen, um Zugang zu erhalten

Abstract

Objective

We sought to evaluate clinical and oncologic outcomes of selected patients with locally advanced breast cancer undergoing full thickness chest wall resection (FTCWR) and reconstruction in a multidisciplinary setting.

Patients and methods

Between 2008 and 2010, five women underwent FTCWR followed by chest wall repair for locally advanced primary breast cancer. In all cases, chest wall repair was performed with a Peri-Guard Repair Patch (Synovis, St. Paul, MN, USA). At follow-up (7–12 months) quality of life, respiratory function and oncologic status were assessed.

Results

Successful chest wall resection and repair were achieved in all patients. Plastic reconstruction of post-mastectomy tissue defects was necessary in one case. One patient was treated by breast conserving therapy. Chest ultrasound imaging confirmed absence of adhesions, haematoma or seroma and normal expansion and respiratory movement of the underlying lung in all patients. On follow-up all patients reported good quality of life.

Conclusion

Multidisciplinary surgical approaches to chest wall resection and reconstruction in selected patients with locally advanced primary breast cancer are feasible, safe, associated with short operation time and hospital stay and negligible morbidity.
Literatur
1.
Zurück zum Zitat Hortobagyi GN, Pritchard K, Amadori D, Haidinger R, Hudis CA, Khaled H, Liu MC, Martin M, Namer M, O’Shaughnessy JA, Shen ZZ, Albain KS, ABREAST Investigators (2005) The global breast cancer burden: variations in epidemiology and survival. Clin Breast Cancer 6:391–401PubMedCrossRef Hortobagyi GN, Pritchard K, Amadori D, Haidinger R, Hudis CA, Khaled H, Liu MC, Martin M, Namer M, O’Shaughnessy JA, Shen ZZ, Albain KS, ABREAST Investigators (2005) The global breast cancer burden: variations in epidemiology and survival. Clin Breast Cancer 6:391–401PubMedCrossRef
2.
Zurück zum Zitat Harris JR, Lippman ME, Morrow M, Osborne CK (2010) Diseases of the breast, 4th edn. Lippincott Williams and Wilkins, Philadelphia, p 492 Harris JR, Lippman ME, Morrow M, Osborne CK (2010) Diseases of the breast, 4th edn. Lippincott Williams and Wilkins, Philadelphia, p 492
3.
Zurück zum Zitat Kroll SS, Schusterman MA, Larson DL, Fender A (1990) Long time survival after chest wall reconstruction with musculocutaneous flaps. Plast Reconstr Surg 86:697–701PubMedCrossRef Kroll SS, Schusterman MA, Larson DL, Fender A (1990) Long time survival after chest wall reconstruction with musculocutaneous flaps. Plast Reconstr Surg 86:697–701PubMedCrossRef
4.
Zurück zum Zitat Downey RJ, Rusch V, Hsu FI, Leon L, Venkatraman E, Linehan D, Bains M, van Zee K, Korst R, Ginsberg R (2000) Chest wall resection for locally recurrent breast cancer: is it worthwhile? J Thorac Cardiovasc Surg 119:420–428PubMedCrossRef Downey RJ, Rusch V, Hsu FI, Leon L, Venkatraman E, Linehan D, Bains M, van Zee K, Korst R, Ginsberg R (2000) Chest wall resection for locally recurrent breast cancer: is it worthwhile? J Thorac Cardiovasc Surg 119:420–428PubMedCrossRef
5.
Zurück zum Zitat Wiegmann B, Zardo P, Dickgreber N, Länger F, Fegbeutel C, Haverich A, Fischer S (2010) Biological materials in chest wall reconstruction: initial experience with the peri-guard repair patch. Eur J Cardiothorac Surg 37:602–605PubMedCrossRef Wiegmann B, Zardo P, Dickgreber N, Länger F, Fegbeutel C, Haverich A, Fischer S (2010) Biological materials in chest wall reconstruction: initial experience with the peri-guard repair patch. Eur J Cardiothorac Surg 37:602–605PubMedCrossRef
6.
Zurück zum Zitat Hathaway CL, Rand RP, Moe R, Marchioro T (1994) Salvage surgery for locally advanced breast cancer and locally recurrent breast cancer. Arch Surg 129:582–587PubMedCrossRef Hathaway CL, Rand RP, Moe R, Marchioro T (1994) Salvage surgery for locally advanced breast cancer and locally recurrent breast cancer. Arch Surg 129:582–587PubMedCrossRef
7.
Zurück zum Zitat Veronesi G, Scanagatta P, Goldhirsch A, Rietjens M, Colleoni M, Pelosi G, Spaggiari L (2007) Results of chest wall resection for recurrent or locally advanced breast malignancies. Breast 16:297–302PubMedCrossRef Veronesi G, Scanagatta P, Goldhirsch A, Rietjens M, Colleoni M, Pelosi G, Spaggiari L (2007) Results of chest wall resection for recurrent or locally advanced breast malignancies. Breast 16:297–302PubMedCrossRef
8.
Zurück zum Zitat Faneyte IF, Rutgers EJ, Zoetmulder FA (1997) Chest wall resection in the treatment of locally recurrent breast carcinoma: indications and outcome for 44 patients. Cancer 80:886–891PubMedCrossRef Faneyte IF, Rutgers EJ, Zoetmulder FA (1997) Chest wall resection in the treatment of locally recurrent breast carcinoma: indications and outcome for 44 patients. Cancer 80:886–891PubMedCrossRef
9.
Zurück zum Zitat Santillan AA, Kiluk JV, Cox JM, Meade TL, Allred N, Ramos D, King J, Cox CE (2008) Outcomes of locoregional recurrence after surgical chest wall resection and reconstruction for breast cancer. Ann Surg Oncol 15:1322–1329PubMedCrossRef Santillan AA, Kiluk JV, Cox JM, Meade TL, Allred N, Ramos D, King J, Cox CE (2008) Outcomes of locoregional recurrence after surgical chest wall resection and reconstruction for breast cancer. Ann Surg Oncol 15:1322–1329PubMedCrossRef
10.
Zurück zum Zitat Chen KN, Yu P (2006) Significance of multidisciplinary surgery in chest wall resection and reconstruction for selected patients with breast cancer. Zhonghua Zhong Liu Za Zhi 28:856–859PubMed Chen KN, Yu P (2006) Significance of multidisciplinary surgery in chest wall resection and reconstruction for selected patients with breast cancer. Zhonghua Zhong Liu Za Zhi 28:856–859PubMed
11.
Zurück zum Zitat Qin X, Tang H, Xu Z, Zhao X, Sun Y, Gong Z, Duan L (2008) Chest wall reconstruction with two types of biodegradable polymer prostheses in dogs. Eur J Cardiothorac Surg 34:870–874PubMedCrossRef Qin X, Tang H, Xu Z, Zhao X, Sun Y, Gong Z, Duan L (2008) Chest wall reconstruction with two types of biodegradable polymer prostheses in dogs. Eur J Cardiothorac Surg 34:870–874PubMedCrossRef
12.
Zurück zum Zitat Weyant MJ, Bains MS, Venkatraman E, Downey RJ, Park BJ, Flores RM, Rizk N, Rusch VW (2006) Results of chest wall resection and reconstruction with and without rigid prosthesis. Ann Thorac Surg 81:279–285PubMedCrossRef Weyant MJ, Bains MS, Venkatraman E, Downey RJ, Park BJ, Flores RM, Rizk N, Rusch VW (2006) Results of chest wall resection and reconstruction with and without rigid prosthesis. Ann Thorac Surg 81:279–285PubMedCrossRef
Metadaten
Titel
Chest wall resection and reconstruction for locally advanced primary breast cancer
verfasst von
Ursula Hille
Philipp Soergel
Patrick Zardo
Stefanie Pertschy
Kai Busch
Stefan Fischer
Publikationsdatum
01.06.2013
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 6/2013
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-012-2682-y

Weitere Artikel der Ausgabe 6/2013

Archives of Gynecology and Obstetrics 6/2013 Zur Ausgabe

Mehr Lebenszeit mit Abemaciclib bei fortgeschrittenem Brustkrebs?

24.05.2024 Mammakarzinom Nachrichten

In der MONARCHE-3-Studie lebten Frauen mit fortgeschrittenem Hormonrezeptor-positivem, HER2-negativem Brustkrebs länger, wenn sie zusätzlich zu einem nicht steroidalen Aromatasehemmer mit Abemaciclib behandelt wurden; allerdings verfehlte der numerische Zugewinn die statistische Signifikanz.

Blutdrucksenkung könnte Uterusmyome verhindern

Frauen mit unbehandelter oder neu auftretender Hypertonie haben ein deutlich erhöhtes Risiko für Uterusmyome. Eine Therapie mit Antihypertensiva geht hingegen mit einer verringerten Inzidenz der gutartigen Tumoren einher.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Antikörper-Wirkstoff-Konjugat hält solide Tumoren in Schach

16.05.2024 Zielgerichtete Therapie Nachrichten

Trastuzumab deruxtecan scheint auch jenseits von Lungenkrebs gut gegen solide Tumoren mit HER2-Mutationen zu wirken. Dafür sprechen die Daten einer offenen Pan-Tumor-Studie.

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.