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01.03.2016 | Head and Neck

Clinical significance of three-dimensional measurement of tumour thickness on magnetic resonance imaging in patients with oral tongue squamous cell carcinoma

verfasst von: Minsu Kwon, Hyun Moon, Soon Yuhl Nam, Jeong Hyun Lee, Ji Won Kim, Yoon-Se Lee, Jong-Lyel Roh, Seung-Ho Choi, Sang-Yoon Kim

Erschienen in: European Radiology | Ausgabe 3/2016

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Abstract

Objectives

To identify the clinical significance of primary tumour thickness (TT) and its direction in patients with oral tongue squamous cell carcinoma (OTSCC), we measured TT in all axial/coronal/sagittal views on magnetic resonance imaging (MRI) and evaluated their meaning.

Methods

A total of 53 OTSCC patients were analysed who had undergone preoperative three-dimensional MRI and had been surgically treated. TT measured on axial (mediolateral direction), coronal (superoinferior direction), and sagittal (anteroposterior direction) views was compared to that in pathologic specimens. The association between TT on MRI and other pathologic parameters was also evaluated.

Results

TT on MRI in each plane showed relatively high concordance rates with the histological measurements. TT in all three planes was significantly correlated with lymph node (LN) metastasis. Occult LN metastasis was found in 15 of 39 (38.5 %) patients, and the cutoff value of TT in axial/coronal/sagittal MRI predicting occult LN metastasis was 6.7 mm, 7.2 mm, and 12.3 mm, respectively. TT on MRI did not show any significant association with recurrence and survival.

Conclusions

TT on MRI in all three planes showed relatively high coincidence with TT on histopathology and presented a potential cut-off value as a predictive indicator for occult LN metastasis.

Key Points

• Three-dimensional measurement of tumour thickness (TT) is important for oral cancer treatment.

• Magnetic resonance imaging (MRI) is a useful diagnostic tool for oral cancer.

• TT on MRI has a high coincidence with TT on histopathology.

• TT on MRI is a predictive marker for occult lymph node metastasis.

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Titel: Clinical significance of three-dimensional measurement of tumour thickness on magnetic resonance imaging in patients with oral tongue squamous cell carcinoma
verfasst von: Minsu Kwon
Hyun Moon
Soon Yuhl Nam
Jeong Hyun Lee
Ji Won Kim
Yoon-Se Lee
Jong-Lyel Roh
Seung-Ho Choi
Sang-Yoon Kim
Publikationsdatum: 01.03.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 3/2016
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-015-3884-z

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Clinical significance of three-dimensional measurement of tumour thickness on magnetic resonance imaging in patients with oral tongue squamous cell carcinoma