Skip to main content
Erschienen in: Osteoporosis International 8/2009

01.08.2009 | Personal View

Cortical and trabecular architecture are altered in postmenopausal women with fractures

verfasst von: E. Sornay-Rendu, S. Boutroy, F. Munoz, M. L. Bouxsein

Erschienen in: Osteoporosis International | Ausgabe 8/2009

Einloggen, um Zugang zu erhalten

Excerpt

On the one-year anniversary of Professor Pierre Delmas’ death, we wish to reflect on his impact on us personally and on the field of osteoporosis research. In the past year, we have had time to think of how extremely fortunate we were to have had the opportunity to work for many years with Prof. Delmas. Elisabeth Sornay-Rendu has served as the primary clinical investigator of the OFELY study since its inception, development and implementation 18 years ago; Françoise Munoz has served as the research unit statistician since 2000; Stephanie Boutroy joined the unit in 2004 as an engineer, and completed her PhD on the in vivo assessment of bone microarchitecture in 2008; and Mary Bouxsein joined the unit as a biomechanics consultant and collaborator in 2003. …
Literatur
1.
Zurück zum Zitat Anonymous (1993) Consensus development conference: prophylaxis and treatment of osteoporosis. Am J Med 94:646–650CrossRef Anonymous (1993) Consensus development conference: prophylaxis and treatment of osteoporosis. Am J Med 94:646–650CrossRef
2.
Zurück zum Zitat Ulrich D, van Rietbergen B, Laib A, Rüegsegger P (1999) The ability of three-dimensional structural indices to reflect mechanical aspects of trabecular bone. Bone 25:55–60PubMedCrossRef Ulrich D, van Rietbergen B, Laib A, Rüegsegger P (1999) The ability of three-dimensional structural indices to reflect mechanical aspects of trabecular bone. Bone 25:55–60PubMedCrossRef
3.
Zurück zum Zitat Croucher PI, Garrahan NJ, Compston JE (1994) Structural mechanisms of trabecular bone loss in primary osteoporosis: specific disease mechanism or early ageing? Bone Miner 25:111–121PubMedCrossRef Croucher PI, Garrahan NJ, Compston JE (1994) Structural mechanisms of trabecular bone loss in primary osteoporosis: specific disease mechanism or early ageing? Bone Miner 25:111–121PubMedCrossRef
4.
Zurück zum Zitat Kleerekoper M, Villanueva AR, Stanciu J, Sudhaker RD, Parfitt AM (1985) The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures. Calcif Tissue Int 37:594–597PubMedCrossRef Kleerekoper M, Villanueva AR, Stanciu J, Sudhaker RD, Parfitt AM (1985) The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures. Calcif Tissue Int 37:594–597PubMedCrossRef
5.
Zurück zum Zitat Kimmel DB, Recker RR, Gallagher JC, Vaswani AS, Aloia JF (1990) A comparison of iliac bone histomorphometric data in post-menopausal osteoporotic and normal subjects. Bone Miner 11:217–35PubMedCrossRef Kimmel DB, Recker RR, Gallagher JC, Vaswani AS, Aloia JF (1990) A comparison of iliac bone histomorphometric data in post-menopausal osteoporotic and normal subjects. Bone Miner 11:217–35PubMedCrossRef
6.
7.
Zurück zum Zitat Boutroy S, Bouxsein ML, Munoz F, Delmas PD (2005) In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Metab 90:6508–15PubMedCrossRef Boutroy S, Bouxsein ML, Munoz F, Delmas PD (2005) In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Metab 90:6508–15PubMedCrossRef
8.
Zurück zum Zitat Sornay-Rendu E, Boutroy S, Munoz F, Delmas PD (2007) Alterations of cortical and trabecular architecture are associated with fractures in postmenopausal women, partially independent of decreased BMD measured by DXA: the OFELY study. J Bone Miner Res 22:425–433PubMedCrossRef Sornay-Rendu E, Boutroy S, Munoz F, Delmas PD (2007) Alterations of cortical and trabecular architecture are associated with fractures in postmenopausal women, partially independent of decreased BMD measured by DXA: the OFELY study. J Bone Miner Res 22:425–433PubMedCrossRef
9.
Zurück zum Zitat Boutroy S, van Rietbergen B, Sornay-Rendu E, Munoz F, Bouxsein ML, Delmas PD (2008) Finite element analyses based on in vivo HR-pQCT images of the distal radius is associated with wrist fracture in postmenopausal women. J Bone Miner Res 23:392–399PubMedCrossRef Boutroy S, van Rietbergen B, Sornay-Rendu E, Munoz F, Bouxsein ML, Delmas PD (2008) Finite element analyses based on in vivo HR-pQCT images of the distal radius is associated with wrist fracture in postmenopausal women. J Bone Miner Res 23:392–399PubMedCrossRef
10.
Zurück zum Zitat Arlot ME, Sornay-Rendu E, Garnero P, Vey-Marty B, Delmas PD (1997) Apparent pre- and postmenopausal bone loss evaluatedby DXA at different skeletal sites in women: the OFELY Cohort. J Bone Miner Res 12:683–690PubMedCrossRef Arlot ME, Sornay-Rendu E, Garnero P, Vey-Marty B, Delmas PD (1997) Apparent pre- and postmenopausal bone loss evaluatedby DXA at different skeletal sites in women: the OFELY Cohort. J Bone Miner Res 12:683–690PubMedCrossRef
11.
Zurück zum Zitat Garnero P, Sornay-Rendu E, Chapuy MC, Delmas PD (1996) Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. J Bone Miner Res 11:337–349PubMedCrossRef Garnero P, Sornay-Rendu E, Chapuy MC, Delmas PD (1996) Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. J Bone Miner Res 11:337–349PubMedCrossRef
12.
Zurück zum Zitat Ritzel H, Amling M, Posl M, Hahn M, Delling G (1997) The thickness of human vertebral cortical bone and its changes in aging and osteoporosis: a histomorphometric analysis of the complete spinal column from thirty-seven autopsy specimens. J Bone Miner Res 12:89–95PubMedCrossRef Ritzel H, Amling M, Posl M, Hahn M, Delling G (1997) The thickness of human vertebral cortical bone and its changes in aging and osteoporosis: a histomorphometric analysis of the complete spinal column from thirty-seven autopsy specimens. J Bone Miner Res 12:89–95PubMedCrossRef
13.
Zurück zum Zitat Foldes J, Parfitt AM, Shih MS, Rao DS, Kleerekoper M (1991) Structural and geometric changes in iliac bone: relationship to normal aging and osteoporosis. J Bone Miner Res 6:759–766PubMedCrossRef Foldes J, Parfitt AM, Shih MS, Rao DS, Kleerekoper M (1991) Structural and geometric changes in iliac bone: relationship to normal aging and osteoporosis. J Bone Miner Res 6:759–766PubMedCrossRef
14.
Zurück zum Zitat Oleksik A, Ott SM, Vedi S, Bravenboer N, Compston J, Lips P (2000) Bone structure in patients with low bone mineral density with or without vertebral fractures. J Bone Miner Res 15:1368–1375PubMedCrossRef Oleksik A, Ott SM, Vedi S, Bravenboer N, Compston J, Lips P (2000) Bone structure in patients with low bone mineral density with or without vertebral fractures. J Bone Miner Res 15:1368–1375PubMedCrossRef
15.
Zurück zum Zitat Schneider P, Reiners C, Cointry GR, Capozza RF, Ferretti JL (2001) Bone quality parameters of the distal radius as assessed by pQCT in normal and fractured women. Osteoporos Int 12:639–646PubMedCrossRef Schneider P, Reiners C, Cointry GR, Capozza RF, Ferretti JL (2001) Bone quality parameters of the distal radius as assessed by pQCT in normal and fractured women. Osteoporos Int 12:639–646PubMedCrossRef
16.
Zurück zum Zitat MacIntyre NJ, Adachi JD, Webber CE (2003) In vivo measurement of apparent trabecular bone structure of the radius in women with low bone density discriminates patients with recent wrist fracture from those without fracture. J Clin Densitometry 6:35–43CrossRef MacIntyre NJ, Adachi JD, Webber CE (2003) In vivo measurement of apparent trabecular bone structure of the radius in women with low bone density discriminates patients with recent wrist fracture from those without fracture. J Clin Densitometry 6:35–43CrossRef
17.
Zurück zum Zitat Gordon CL, Lang TF, Augat P, Genant HK (1998) Image-based assessment of spinal trabecular bone structure from high-resolution CT images. Osteoporos Int 8:317–325PubMedCrossRef Gordon CL, Lang TF, Augat P, Genant HK (1998) Image-based assessment of spinal trabecular bone structure from high-resolution CT images. Osteoporos Int 8:317–325PubMedCrossRef
18.
Zurück zum Zitat Ito M, Ikeda K, Nishiguchi M, Shindo H, Uetani M, Hosoi T, Orimo H (2005) Multi-detector row CT imaging of vertebral microstructure for evaluation of fracture risk. J Bone Miner Res 20:1828–1836PubMedCrossRef Ito M, Ikeda K, Nishiguchi M, Shindo H, Uetani M, Hosoi T, Orimo H (2005) Multi-detector row CT imaging of vertebral microstructure for evaluation of fracture risk. J Bone Miner Res 20:1828–1836PubMedCrossRef
19.
Zurück zum Zitat Majumdar S, Link TM, Augat P, Lin JC, Newitt D, Lane NE, Genant HK (1999) Trabecular bone architecture in the distal radius using magnetic resonance imaging in subjects with fractures of the proximal femur. Osteoporos Int 10:231–239PubMedCrossRef Majumdar S, Link TM, Augat P, Lin JC, Newitt D, Lane NE, Genant HK (1999) Trabecular bone architecture in the distal radius using magnetic resonance imaging in subjects with fractures of the proximal femur. Osteoporos Int 10:231–239PubMedCrossRef
20.
Zurück zum Zitat Laib A, Nevitt DC, Lu Y, Majumdar S (2002) New model independent measures of trabecular bone structure applied to in vivo high-resolution MR images. Osteoporos Int 13:130–136PubMedCrossRef Laib A, Nevitt DC, Lu Y, Majumdar S (2002) New model independent measures of trabecular bone structure applied to in vivo high-resolution MR images. Osteoporos Int 13:130–136PubMedCrossRef
21.
Zurück zum Zitat Muller ME, Webber CE, Bouxsein ML (2003) Predicting the failure load of the distal radius. Osteoporos Int 14:345–352PubMedCrossRef Muller ME, Webber CE, Bouxsein ML (2003) Predicting the failure load of the distal radius. Osteoporos Int 14:345–352PubMedCrossRef
Metadaten
Titel
Cortical and trabecular architecture are altered in postmenopausal women with fractures
verfasst von
E. Sornay-Rendu
S. Boutroy
F. Munoz
M. L. Bouxsein
Publikationsdatum
01.08.2009
Verlag
Springer-Verlag
Erschienen in
Osteoporosis International / Ausgabe 8/2009
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-009-1008-9

Weitere Artikel der Ausgabe 8/2009

Osteoporosis International 8/2009 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Klinik aktuell Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

Aquatherapie bei Fibromyalgie wirksamer als Trockenübungen

03.05.2024 Fibromyalgiesyndrom Nachrichten

Bewegungs-, Dehnungs- und Entspannungsübungen im Wasser lindern die Beschwerden von Patientinnen mit Fibromyalgie besser als das Üben auf trockenem Land. Das geht aus einer spanisch-brasilianischen Vergleichsstudie hervor.

Endlich: Zi zeigt, mit welchen PVS Praxen zufrieden sind

IT für Ärzte Nachrichten

Darauf haben viele Praxen gewartet: Das Zi hat eine Liste von Praxisverwaltungssystemen veröffentlicht, die von Nutzern positiv bewertet werden. Eine gute Grundlage für wechselwillige Ärztinnen und Psychotherapeuten.

Proximale Humerusfraktur: Auch 100-Jährige operieren?

01.05.2024 DCK 2024 Kongressbericht

Mit dem demographischen Wandel versorgt auch die Chirurgie immer mehr betagte Menschen. Von Entwicklungen wie Fast-Track können auch ältere Menschen profitieren und bei proximaler Humerusfraktur können selbst manche 100-Jährige noch sicher operiert werden.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.