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Erschienen in: Die Diabetologie 5/2022

29.06.2022 | Im Fokus

Diabetes mellitus 2022 – Was ist neu?

verfasst von: Univ.-Prof. Dr. med. Werner A. Scherbaum

Erschienen in: Die Diabetologie | Ausgabe 5/2022

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Im Folgenden sollen die aus Sicht des Autors wichtigsten neuen Erkenntnisse zu den beim Diabetes Update 2022 vorgestellten und in diesem Heft nicht als Artikel erscheinenden Themen kurz beschrieben werden. Bezüglich der Originaltexte und Kommentare der Referenten wird auf das Original verwiesen [1]. …
Literatur
1.
Zurück zum Zitat Hamann A, Kleinwechter H, Martin S, Stumvoll M (Hrsg) (2022) Update Diabetologie. Seminarunterlagen Diabetes Update 2022 – 17. Diabetologie-Update-Seminar, Mainz Hamann A, Kleinwechter H, Martin S, Stumvoll M (Hrsg) (2022) Update Diabetologie. Seminarunterlagen Diabetes Update 2022 – 17. Diabetologie-Update-Seminar, Mainz
3.
Zurück zum Zitat Sims EK, Bundy BN, Stier K et al (2021) Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals. Sci Transl Med 13(583):eabc8980PubMedPubMedCentralCrossRef Sims EK, Bundy BN, Stier K et al (2021) Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals. Sci Transl Med 13(583):eabc8980PubMedPubMedCentralCrossRef
4.
Zurück zum Zitat Fang Z, Liu M, Tao J et al (2022) Efficacy and safety of closed-loop insulin delivery versus sensor-augmented pump in the treatment of adults with type 1 diabetes: a systematic review and meta-analysis of randomized-controlled trials. J Endocrinol Invest 45(3):471–481PubMedCrossRef Fang Z, Liu M, Tao J et al (2022) Efficacy and safety of closed-loop insulin delivery versus sensor-augmented pump in the treatment of adults with type 1 diabetes: a systematic review and meta-analysis of randomized-controlled trials. J Endocrinol Invest 45(3):471–481PubMedCrossRef
6.
Zurück zum Zitat Forlenza GP, Buckingham BA, Brown SA et al (2021) First outpatient evaluation of a tubeless automated insulin delivery system with customizable glucose targets in children and adults with type 1 diabetes. Diabetes Technol Ther 23:410–424PubMedPubMedCentralCrossRef Forlenza GP, Buckingham BA, Brown SA et al (2021) First outpatient evaluation of a tubeless automated insulin delivery system with customizable glucose targets in children and adults with type 1 diabetes. Diabetes Technol Ther 23:410–424PubMedPubMedCentralCrossRef
7.
Zurück zum Zitat Holt RIG, DeVries JH, Hess-Frischl A et al (2021) The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association fort he Study of Diabetes (EASD). Diabetologia 64:2609–2652PubMedPubMedCentralCrossRef Holt RIG, DeVries JH, Hess-Frischl A et al (2021) The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association fort he Study of Diabetes (EASD). Diabetologia 64:2609–2652PubMedPubMedCentralCrossRef
8.
Zurück zum Zitat Schlüter S, Freckmann G, Heinemann L et al (2021) Evaluation of the SPECTRUM training programme for real-time continuous glucose monitoring. A real-world multicentre prospective study in 120 adults with type 1 diabetes. Diabet Med 38(2):e14467PubMedCrossRef Schlüter S, Freckmann G, Heinemann L et al (2021) Evaluation of the SPECTRUM training programme for real-time continuous glucose monitoring. A real-world multicentre prospective study in 120 adults with type 1 diabetes. Diabet Med 38(2):e14467PubMedCrossRef
9.
Zurück zum Zitat Riddle MC, Cefalu WT, Evans PH et al (2021) Consensus Report: definition and interpretation of remission in type 2 diabetes. Diabetes Care 44(10):2438–3444CrossRef Riddle MC, Cefalu WT, Evans PH et al (2021) Consensus Report: definition and interpretation of remission in type 2 diabetes. Diabetes Care 44(10):2438–3444CrossRef
10.
11.
Zurück zum Zitat Yurista SR, Chong CR, Badimon JJ et al (2021) Therapeutic potential of ketone bodies for patients with cardiovascular disease: JACC State-Of-The-Art Review. J Am Coll Cardiol 77(13):1660–1669PubMedCrossRef Yurista SR, Chong CR, Badimon JJ et al (2021) Therapeutic potential of ketone bodies for patients with cardiovascular disease: JACC State-Of-The-Art Review. J Am Coll Cardiol 77(13):1660–1669PubMedCrossRef
12.
Zurück zum Zitat Pietschner R, Kolwelter J, Bosch A et al (2021) Effect of empagliflozine on ketone bodies in patients with stable chronic heart failure. Cardiovasc Diabetol 20(1):219PubMedPubMedCentralCrossRef Pietschner R, Kolwelter J, Bosch A et al (2021) Effect of empagliflozine on ketone bodies in patients with stable chronic heart failure. Cardiovasc Diabetol 20(1):219PubMedPubMedCentralCrossRef
13.
Zurück zum Zitat Hirschberger S, Strauß G, Effinger D et al (2021) Very-low carbohydrate diet enhances human T cell immunity through immunometabolic reprogramming. EMBO Mol Med 13(8):e14323PubMedPubMedCentralCrossRef Hirschberger S, Strauß G, Effinger D et al (2021) Very-low carbohydrate diet enhances human T cell immunity through immunometabolic reprogramming. EMBO Mol Med 13(8):e14323PubMedPubMedCentralCrossRef
14.
Zurück zum Zitat Johannesen CDL, Mortensen MBMB, Lansted A et al (2021) Apolipoprotein B and Non-HDL cholesterol better reflect rsidual risk thaqn LDL cholesterol in Statin-treated in patients with type 2 diabetes: a meta-analysis. J Am Coll Cardiol 77:1439–1450PubMedCrossRef Johannesen CDL, Mortensen MBMB, Lansted A et al (2021) Apolipoprotein B and Non-HDL cholesterol better reflect rsidual risk thaqn LDL cholesterol in Statin-treated in patients with type 2 diabetes: a meta-analysis. J Am Coll Cardiol 77:1439–1450PubMedCrossRef
15.
Zurück zum Zitat McDonagh TA, Metra M, Adamo M et al (2021) 2021 EDS Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 42:3599–3726PubMedCrossRef McDonagh TA, Metra M, Adamo M et al (2021) 2021 EDS Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 42:3599–3726PubMedCrossRef
16.
Zurück zum Zitat Anker SD, Butler J, Filippatos G et al (2021) Empagliflozin in heart failure with a preserved ejection fraction. N Engl J Med 385:1451–1461PubMedCrossRef Anker SD, Butler J, Filippatos G et al (2021) Empagliflozin in heart failure with a preserved ejection fraction. N Engl J Med 385:1451–1461PubMedCrossRef
17.
Zurück zum Zitat McGuire DK, Shih WJ, Cosentino F et al (2021) Association of SGLT2 inhibitors with cardiovascular and kidney outcomes in patients with type 2 diabetes: a meta-analysis. JAMA Cardiol 6(2):148–158PubMedCrossRef McGuire DK, Shih WJ, Cosentino F et al (2021) Association of SGLT2 inhibitors with cardiovascular and kidney outcomes in patients with type 2 diabetes: a meta-analysis. JAMA Cardiol 6(2):148–158PubMedCrossRef
18.
Zurück zum Zitat Bergstrom G, Persson M, Adiels M et al (2021) Prevalence of subclinincal coronary artery atherosclerosis in the general population. Circulation 144:916–929PubMedPubMedCentralCrossRef Bergstrom G, Persson M, Adiels M et al (2021) Prevalence of subclinincal coronary artery atherosclerosis in the general population. Circulation 144:916–929PubMedPubMedCentralCrossRef
19.
Zurück zum Zitat Reynolds HR, Shaw LJ, Min JK et al (2021) Outcomes in the ISCHEMIA trial based on coronary artery disease and ischemia severity. Circulation 144(13):1024–1038PubMedCrossRef Reynolds HR, Shaw LJ, Min JK et al (2021) Outcomes in the ISCHEMIA trial based on coronary artery disease and ischemia severity. Circulation 144(13):1024–1038PubMedCrossRef
20.
Zurück zum Zitat Salah HM, Al’Aref SJ, Khan MS et al (2021) Effect of sodium-glucose cotransporter 2 inhibitors on cardiovascular and renal outcomes—Systematic review and meta-analysis of randomised placebo-conzrolled trials. Am Heart J 232:10–22PubMedCrossRef Salah HM, Al’Aref SJ, Khan MS et al (2021) Effect of sodium-glucose cotransporter 2 inhibitors on cardiovascular and renal outcomes—Systematic review and meta-analysis of randomised placebo-conzrolled trials. Am Heart J 232:10–22PubMedCrossRef
21.
Zurück zum Zitat Chertow GM, Vart P, Jongs N et al (2021) Effects of dapagliflozin in stage 4 chronic kidney disease. J Am Soc Nephrol 32:2352–2361PubMedCrossRef Chertow GM, Vart P, Jongs N et al (2021) Effects of dapagliflozin in stage 4 chronic kidney disease. J Am Soc Nephrol 32:2352–2361PubMedCrossRef
22.
Zurück zum Zitat McMurray JJV, Wheeler DC, Stefansson BV et al (2021) Effect of dapagliflozin on clinical outcomes in patients with chronic kdney disease. Circulation 143:438–448PubMedCrossRef McMurray JJV, Wheeler DC, Stefansson BV et al (2021) Effect of dapagliflozin on clinical outcomes in patients with chronic kdney disease. Circulation 143:438–448PubMedCrossRef
23.
Zurück zum Zitat Wheeler DC, Toto RD, Stevansson BV et al (2021) A pre-specified analysis oft he DAPA-CKD trial demonstrates the effects of dapagliflocin on major adverse kidney events in pathients with OgA nephropathy. Kidney Int 100:215–224PubMedCrossRef Wheeler DC, Toto RD, Stevansson BV et al (2021) A pre-specified analysis oft he DAPA-CKD trial demonstrates the effects of dapagliflocin on major adverse kidney events in pathients with OgA nephropathy. Kidney Int 100:215–224PubMedCrossRef
25.
Zurück zum Zitat Ji Q, Ji L, Zhao J et al (2021) Effect of empagliflozin on cardiorenal outcomes and mortality according to body mass index: a subgroup analysis of the EMPA-REG OUTCOME trial with a focus on asia. Diabetes Obes Metab 23:1886–1891PubMedPubMedCentralCrossRef Ji Q, Ji L, Zhao J et al (2021) Effect of empagliflozin on cardiorenal outcomes and mortality according to body mass index: a subgroup analysis of the EMPA-REG OUTCOME trial with a focus on asia. Diabetes Obes Metab 23:1886–1891PubMedPubMedCentralCrossRef
26.
Zurück zum Zitat Jardine M, Zhou Z, Heerspink HJL et al (2021) Kidney, cardiovascular, and safety outcomes of canagliflozin according to baseline albuminuria: a CREDENCE secondary analysis. Clin J Am Soc Nephrol 16:384–395PubMedPubMedCentralCrossRef Jardine M, Zhou Z, Heerspink HJL et al (2021) Kidney, cardiovascular, and safety outcomes of canagliflozin according to baseline albuminuria: a CREDENCE secondary analysis. Clin J Am Soc Nephrol 16:384–395PubMedPubMedCentralCrossRef
28.
Zurück zum Zitat Chow CK, Atkins ER, Hillis GS et al (2021) Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial. Lancet 398:1043–1052PubMedCrossRef Chow CK, Atkins ER, Hillis GS et al (2021) Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial. Lancet 398:1043–1052PubMedCrossRef
29.
Zurück zum Zitat Neal B, Wu Y, Feng X et al (2021) Effect of salt sunstitution on cardiovascular events and death. N Engl J Mae 385:1067–1077CrossRef Neal B, Wu Y, Feng X et al (2021) Effect of salt sunstitution on cardiovascular events and death. N Engl J Mae 385:1067–1077CrossRef
30.
Zurück zum Zitat Amarenco P, Kim JS, Labreuche J et al (2020) A comparison of two LDL cholesterol targets after ischaemic stroke. N Engl J Med 382(1):9–19PubMedCrossRef Amarenco P, Kim JS, Labreuche J et al (2020) A comparison of two LDL cholesterol targets after ischaemic stroke. N Engl J Med 382(1):9–19PubMedCrossRef
31.
Zurück zum Zitat Bosch J, Lonn EM, Dagenais GR et al (2021) Antihypertensives and statin therapy for primary stroke prevention: a secondary analysis of the HOPE‑3 trial. Stroke 52(8):2494–2501PubMedCrossRef Bosch J, Lonn EM, Dagenais GR et al (2021) Antihypertensives and statin therapy for primary stroke prevention: a secondary analysis of the HOPE‑3 trial. Stroke 52(8):2494–2501PubMedCrossRef
32.
Zurück zum Zitat Liampas A, Rekatsina M, Vadalouca A et al (2021) Pharmacological management of painful peripheral neuropathies. A systematic review. Pain Ther 10(1):55–68PubMedCrossRef Liampas A, Rekatsina M, Vadalouca A et al (2021) Pharmacological management of painful peripheral neuropathies. A systematic review. Pain Ther 10(1):55–68PubMedCrossRef
33.
Zurück zum Zitat Price R, Smith D, Franklin G et al (2022) Oral and topical treatment of painful diabetic polyneuropathy: Practice Guideline Update Summary: Report oft he AAN Guideline Subcommittee. Neurology 98(1):31–43PubMedCrossRef Price R, Smith D, Franklin G et al (2022) Oral and topical treatment of painful diabetic polyneuropathy: Practice Guideline Update Summary: Report oft he AAN Guideline Subcommittee. Neurology 98(1):31–43PubMedCrossRef
34.
Zurück zum Zitat Bahron RJ, Gajewski B, Pasnoor M et al (2021) Patient assisted intervention for neuropathy: a comparison of treatment in real life situations (PAIN-CONTRoLS): Bayesian adaptive comparative effectiveness randomized trial. JAMA Neurol 78(1):68–76CrossRef Bahron RJ, Gajewski B, Pasnoor M et al (2021) Patient assisted intervention for neuropathy: a comparison of treatment in real life situations (PAIN-CONTRoLS): Bayesian adaptive comparative effectiveness randomized trial. JAMA Neurol 78(1):68–76CrossRef
35.
Zurück zum Zitat Vas P, Rayman G, Dhatariya K et al (2020) Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: a systematic review. Diabetes Metab Res Rev 36(S1):e3284PubMedCrossRef Vas P, Rayman G, Dhatariya K et al (2020) Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: a systematic review. Diabetes Metab Res Rev 36(S1):e3284PubMedCrossRef
36.
Zurück zum Zitat Tettelbach W, Cazzell S, Reyzelman AM (2019) A confirmatory study on the efficacy of dehydrated human amnion/choronic membrane dHACM allograft in the management of diabetic foot ulcers: A prospective, multicentre, randomised, controlled study of 110 patients from 14 wound clinics. Int Wound J 16(1):19–29PubMedCrossRef Tettelbach W, Cazzell S, Reyzelman AM (2019) A confirmatory study on the efficacy of dehydrated human amnion/choronic membrane dHACM allograft in the management of diabetic foot ulcers: A prospective, multicentre, randomised, controlled study of 110 patients from 14 wound clinics. Int Wound J 16(1):19–29PubMedCrossRef
37.
Zurück zum Zitat Game F, Gray K, Davis D et al (2021) The effectiveness of a new dried human amnion derived membrane in addition to standard care in treating diabetic foot ulcers: A patient and asessor blind, randomised controlled pilot study. Int Wound J 18(5):692–700PubMedPubMedCentralCrossRef Game F, Gray K, Davis D et al (2021) The effectiveness of a new dried human amnion derived membrane in addition to standard care in treating diabetic foot ulcers: A patient and asessor blind, randomised controlled pilot study. Int Wound J 18(5):692–700PubMedPubMedCentralCrossRef
38.
Zurück zum Zitat Seidel D, Storck M, Lawall H et al (2020) Negative pressure wound therapy comparen with standard moist wound care on diabetic foot ulcers in real-life clinical practice: results oft he German DiaFu-RCT. BMJ Open 10(3):e26345PubMedPubMedCentralCrossRef Seidel D, Storck M, Lawall H et al (2020) Negative pressure wound therapy comparen with standard moist wound care on diabetic foot ulcers in real-life clinical practice: results oft he German DiaFu-RCT. BMJ Open 10(3):e26345PubMedPubMedCentralCrossRef
39.
Zurück zum Zitat Khneizer G, Rizvi S, Gawrieh S (2021) Non-alcoholic fatty liver disease and diabetes mellitus. Adv Exp Biol 1307:417–440CrossRef Khneizer G, Rizvi S, Gawrieh S (2021) Non-alcoholic fatty liver disease and diabetes mellitus. Adv Exp Biol 1307:417–440CrossRef
42.
Zurück zum Zitat Wu J, He H, Zhang Q et al (2021) Fasting blood glucose was linearly associated with colorectal cancer risk in the population without self-reported diabetes melllitus history. Medicine 100(34):e26974PubMedPubMedCentralCrossRef Wu J, He H, Zhang Q et al (2021) Fasting blood glucose was linearly associated with colorectal cancer risk in the population without self-reported diabetes melllitus history. Medicine 100(34):e26974PubMedPubMedCentralCrossRef
43.
Zurück zum Zitat Agha OQ, Alsyid M, Brown MD (2021) Bowel preparation in diabetic patients undergoing colonoscopy. Ann Gastroenterol 34(3):310–315PubMedPubMedCentral Agha OQ, Alsyid M, Brown MD (2021) Bowel preparation in diabetic patients undergoing colonoscopy. Ann Gastroenterol 34(3):310–315PubMedPubMedCentral
44.
Zurück zum Zitat Petrov MS, Basina M (2021) Diagnosis of endocrine Disease: Diagnosing and classifying diabetes in diseases oft he exocrine pancreas. Eur J Endocrinol 184(4):R151–R163PubMedCrossRef Petrov MS, Basina M (2021) Diagnosis of endocrine Disease: Diagnosing and classifying diabetes in diseases oft he exocrine pancreas. Eur J Endocrinol 184(4):R151–R163PubMedCrossRef
45.
Zurück zum Zitat Koromani F, Ghatan S, van Hoek M et al (2021) Type 2 diabetes mellitus and vertebral fracture risk. Curr Osteoporos Rep 19(1):50–57PubMedPubMedCentralCrossRef Koromani F, Ghatan S, van Hoek M et al (2021) Type 2 diabetes mellitus and vertebral fracture risk. Curr Osteoporos Rep 19(1):50–57PubMedPubMedCentralCrossRef
46.
Zurück zum Zitat Sihota P, Yadav RN, Dhaliwal R et al (2021) Investigation of mechanical, material, and compositional determinants of human trabecular bone quality in type 2 diabetes. J Clin Endocrinol Metab 106:e2271–e2289PubMedCrossRef Sihota P, Yadav RN, Dhaliwal R et al (2021) Investigation of mechanical, material, and compositional determinants of human trabecular bone quality in type 2 diabetes. J Clin Endocrinol Metab 106:e2271–e2289PubMedCrossRef
47.
Zurück zum Zitat Broadwell A et al (2021) Senosumab safety and efficacy among participants in the FREEDOM Extension and treatment of primary Study with mild to moderate chronic kidney disease. J Clin Endocrinol Metab 106(2):397–409PubMedCrossRef Broadwell A et al (2021) Senosumab safety and efficacy among participants in the FREEDOM Extension and treatment of primary Study with mild to moderate chronic kidney disease. J Clin Endocrinol Metab 106(2):397–409PubMedCrossRef
48.
Zurück zum Zitat Cohen JB, Cohen DL, Herman DS et al (2021) Testing für primary Aldosteronism and mineralocorticoid receptor antagonist use among U.S. veterans: a retrospective cohort study. Ann Intern Med 174:289–297PubMedCrossRef Cohen JB, Cohen DL, Herman DS et al (2021) Testing für primary Aldosteronism and mineralocorticoid receptor antagonist use among U.S. veterans: a retrospective cohort study. Ann Intern Med 174:289–297PubMedCrossRef
49.
Zurück zum Zitat Liu YY, King J, Koline GA et al (2021) Outcomes of a specialized clinic on rates of investigation and treatment ofprimary aldosteronism. JAMA Surg 156:541–549PubMedCrossRef Liu YY, King J, Koline GA et al (2021) Outcomes of a specialized clinic on rates of investigation and treatment ofprimary aldosteronism. JAMA Surg 156:541–549PubMedCrossRef
50.
Zurück zum Zitat Beumer J, Puschhof J, Bauza-Martinez J et al (2020) High-resolution mRNA and secretome atlas of human enteroendocrine cells. Cell 181(e1219):1291–1306PubMedCrossRef Beumer J, Puschhof J, Bauza-Martinez J et al (2020) High-resolution mRNA and secretome atlas of human enteroendocrine cells. Cell 181(e1219):1291–1306PubMedCrossRef
52.
Zurück zum Zitat Le Roux CW, Aylwin SJ, Batterham RL et al (2006) Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters. Ann Surg 243:108–114PubMedPubMedCentralCrossRef Le Roux CW, Aylwin SJ, Batterham RL et al (2006) Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters. Ann Surg 243:108–114PubMedPubMedCentralCrossRef
53.
Zurück zum Zitat Del Prato S, Kahn SE, Pavo I et al (2021) Tirzapatide versus insulin glargine in type‑2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial. Lancet 398:1811–1874PubMedCrossRef Del Prato S, Kahn SE, Pavo I et al (2021) Tirzapatide versus insulin glargine in type‑2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial. Lancet 398:1811–1874PubMedCrossRef
54.
Zurück zum Zitat Nahra R, Wang T, Gadde KM et al (2021) Effects of cotadutide on metabolic and hepatic parameters in adults with overweight and obesity and type 2 diabetes: a 54-week randomized phase 2b study. Diabetes Care 44:1433–1442PubMedPubMedCentralCrossRef Nahra R, Wang T, Gadde KM et al (2021) Effects of cotadutide on metabolic and hepatic parameters in adults with overweight and obesity and type 2 diabetes: a 54-week randomized phase 2b study. Diabetes Care 44:1433–1442PubMedPubMedCentralCrossRef
55.
Zurück zum Zitat Lau DCW, Erichsen L, Francisco AM et al (2021) Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial. Lancet 398(10317):2160–2172PubMedCrossRef Lau DCW, Erichsen L, Francisco AM et al (2021) Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial. Lancet 398(10317):2160–2172PubMedCrossRef
Metadaten
Titel
Diabetes mellitus 2022 – Was ist neu?
verfasst von
Univ.-Prof. Dr. med. Werner A. Scherbaum
Publikationsdatum
29.06.2022
Verlag
Springer Medizin
Erschienen in
Die Diabetologie / Ausgabe 5/2022
Print ISSN: 2731-7447
Elektronische ISSN: 2731-7455
DOI
https://doi.org/10.1007/s11428-022-00924-2

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