Erschienen in:
01.03.2015 | Journal club
Diagnosis and treatment of chronic inflammatory demyelinating polyneuropathy
verfasst von:
Reem A. Amin, N. P. Robertson
Erschienen in:
Journal of Neurology
|
Ausgabe 3/2015
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Excerpt
Chronic inflammatory demyelinating neuropathy (CIDP) is generally considered to be an immune-mediated neuropathy with potential target antigens, although its precise pathogenesis is unclear. Unlike its more acute counterpart, acute inflammatory demyelinating neuropathy, the diagnosis is necessarily delayed as a result of clinical definitions but also the fluctuating clinical manifestations which can evolve over months and years. In addition, as a result of its relative rarity it is not usually definitively diagnosed and treated until patients come into contact with specialist neurology services. However, even within specialist settings the diagnosis is often elusive as a result of heterogeneous clinical manifestations, the patchy nature of the demyelinating pathology and limitations of available diagnostic tests. …