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Heart Failure Reviews
Erschienen in: Heart Failure Reviews 1/2013

01.01.2013

Diastolic ventricular support with cardiac support devices: an alternative approach to prevent adverse ventricular remodeling

verfasst von: Pavan Atluri, Michael A. Acker

Erschienen in: Heart Failure Reviews | Ausgabe 1/2013

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Abstract

Heart failure is a global epidemic with limited therapy. Abnormal left ventricular wall stress in the diseased myocardium results in a biochemical positive feedback loop that results in global ventricular remodeling and further deterioration of myocardial function. Mechanical myocardial restraints such as the Acorn CorCap and Paracor HeartNet ventricular restraints have attempted to minimize diastolic ventricular wall stress and limit adverse ventricular remodeling. Unfortunately, these therapies have not yielded viable clinical therapies for heart failure. Cellular and novel biopolymer-based therapies aimed at stabilizing pathologic myocardium hold promise for translation to clinical therapy in the future.
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Metadaten
Titel
Diastolic ventricular support with cardiac support devices: an alternative approach to prevent adverse ventricular remodeling
verfasst von
Pavan Atluri
Michael A. Acker
Publikationsdatum
01.01.2013
Verlag
Springer US
Erschienen in
Heart Failure Reviews / Ausgabe 1/2013
Print ISSN: 1382-4147
Elektronische ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-012-9312-4

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