Skip to main content
Erschienen in: European Journal of Nutrition 4/2015

01.06.2015 | Original Contribution

Dietary glycaemic load associated with cognitive performance in elderly subjects

verfasst von: Susan E. Power, Eibhlís M. O’Connor, R. Paul Ross, Catherine Stanton, Paul W. O’Toole, Gerald F. Fitzgerald, Ian B. Jeffery

Erschienen in: European Journal of Nutrition | Ausgabe 4/2015

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Ageing is associated with loss of cognitive function and an increased risk of dementia which is expected to place growing demands on health and long-term care providers. Among multiple causative factors, evidence suggests that cognitive impairment in older subjects may be influenced by diet. The objective of this study was to examine the association between dietary patterns, dietary glycaemic load (GL) and cognition in older Irish adults.

Methods

Community-dwelling subjects (n 208; 94 males and 114 females; aged 64–93 years) were analysed. Dietary intake was assessed using a validated semi-quantitative food frequency questionnaire. Cognitive capacity was tested using the Mini-Mental State Examination (MMSE). The data were clustered to derive patterns of dietary intake. Multivariable-adjusted logistic and Poisson regression models were used to examine the relationship between dietary GL and MMSE score.

Results

Elderly subjects consuming ‘prudent’ dietary patterns (high in fruit, vegetables, fish, low-fat dairy and salad dressings and low in red meat and white bread) had higher MMSE scores (better cognitive function) than those consuming ‘Western’ dietary pattern (high in red meat and white bread and low in fruit and vegetables; P < 0.05). Logistic and Poisson regression analyses both indicated that the MMSE score was inversely associated with the GL of the diet (P < 0.05) even after adjusting for age, gender, diabetes, hypertension, healthy food diversity, nutritional status, residential property price, cardiovascular medications and energy intake.

Conclusion

In this community-dwelling elderly Irish cohort, consumption of a high glycaemic diet is associated with poorer cognitive performance as assessed by the MMSE.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
3.
Zurück zum Zitat McGuire LC, Ford ES, Ajani UA (2006) Cognitive functioning as a predictor of functional disability in later life. Am J Geriatr Psychiatry 14(1):36–42CrossRef McGuire LC, Ford ES, Ajani UA (2006) Cognitive functioning as a predictor of functional disability in later life. Am J Geriatr Psychiatry 14(1):36–42CrossRef
4.
Zurück zum Zitat Allès B et al (2012) Dietary patterns: a novel approach to examine the link between nutrition and cognitive function in older individuals. Nutr Res Rev 1(1):1–16 Allès B et al (2012) Dietary patterns: a novel approach to examine the link between nutrition and cognitive function in older individuals. Nutr Res Rev 1(1):1–16
5.
Zurück zum Zitat Parrott MD, Greenwood CE (2007) Dietary influences on cognitive function with aging. Ann NY Acad Sci 1114(1):389–397CrossRef Parrott MD, Greenwood CE (2007) Dietary influences on cognitive function with aging. Ann NY Acad Sci 1114(1):389–397CrossRef
6.
Zurück zum Zitat Francis H, Stevenson R (2013) The longer-term impacts of Western diet on human cognition and the brain. Appetite 63:119–128 Francis H, Stevenson R (2013) The longer-term impacts of Western diet on human cognition and the brain. Appetite 63:119–128
7.
Zurück zum Zitat Kanoski SE, Davidson TL (2011) Western diet consumption and cognitive impairment: links to hippocampal dysfunction and obesity. Physiol Behav 103(1):59–68CrossRef Kanoski SE, Davidson TL (2011) Western diet consumption and cognitive impairment: links to hippocampal dysfunction and obesity. Physiol Behav 103(1):59–68CrossRef
8.
Zurück zum Zitat van Dam RM et al (2002) Dietary patterns and risk for type 2 diabetes mellitus in U.S. Men. Ann Intern Med 136(3):201–209CrossRef van Dam RM et al (2002) Dietary patterns and risk for type 2 diabetes mellitus in U.S. Men. Ann Intern Med 136(3):201–209CrossRef
9.
Zurück zum Zitat Steyn NP et al (2004) Diet, nutrition and the prevention of type 2 diabetes. Public Health Nutr 7(1A; SPI):147–166 Steyn NP et al (2004) Diet, nutrition and the prevention of type 2 diabetes. Public Health Nutr 7(1A; SPI):147–166
10.
Zurück zum Zitat Torres SJ et al (2012) Dietary patterns are associated with cognition among older people with mild cognitive impairment. Nutrients 4(11):1542–1551CrossRef Torres SJ et al (2012) Dietary patterns are associated with cognition among older people with mild cognitive impairment. Nutrients 4(11):1542–1551CrossRef
11.
Zurück zum Zitat Foster-Powell K, Holt SH, Brand-Miller JC (2002) International table of glycemic index and glycemic load values: 2002. Am J Clin Nutr 76(1):5–56 Foster-Powell K, Holt SH, Brand-Miller JC (2002) International table of glycemic index and glycemic load values: 2002. Am J Clin Nutr 76(1):5–56
12.
Zurück zum Zitat Barclay AW, Brand-Miller JC, Wolever TM (2005) Glycemic index, glycemic load, and glycemic response are not the same. Diabetes Care 28(7):1839–1840CrossRef Barclay AW, Brand-Miller JC, Wolever TM (2005) Glycemic index, glycemic load, and glycemic response are not the same. Diabetes Care 28(7):1839–1840CrossRef
13.
Zurück zum Zitat Folstein MF, Folstein SE, McHugh PR (1975) Mini-Mental State: a practical method for grading the cognitive state of patients for the clinician. Pergamon Press Folstein MF, Folstein SE, McHugh PR (1975) Mini-Mental State: a practical method for grading the cognitive state of patients for the clinician. Pergamon Press
14.
Zurück zum Zitat Mungas D (1991) In-office mental status testing: a practical guide. Geriatrics 46(7):54 Mungas D (1991) In-office mental status testing: a practical guide. Geriatrics 46(7):54
15.
Zurück zum Zitat Coffee N et al (2013) Relative residential property value as a socio-economic status indicator for health research. Int J Health Geogr 12(1):22CrossRef Coffee N et al (2013) Relative residential property value as a socio-economic status indicator for health research. Int J Health Geogr 12(1):22CrossRef
16.
Zurück zum Zitat Vellas B et al (1999) The mini nutritional assessment (MNA) and its use in grading the nutritional state of elderly patients. Nutrition 15(2):116–122CrossRef Vellas B et al (1999) The mini nutritional assessment (MNA) and its use in grading the nutritional state of elderly patients. Nutrition 15(2):116–122CrossRef
17.
Zurück zum Zitat Riboli E, Kaaks R (1997) The EPIC project: rationale and study design. European prospective investigation into cancer and nutrition. Int J Epidemiol 26(Supplement 1):S6CrossRef Riboli E, Kaaks R (1997) The EPIC project: rationale and study design. European prospective investigation into cancer and nutrition. Int J Epidemiol 26(Supplement 1):S6CrossRef
18.
Zurück zum Zitat Harrington J et al (2008) SLÁN 2007: survey of lifestyle, attitudes and nutrition in Ireland. Dietary habits of the Irish population. Department of Health and Children (ed) Dublin: The Stationery Office Harrington J et al (2008) SLÁN 2007: survey of lifestyle, attitudes and nutrition in Ireland. Dietary habits of the Irish population. Department of Health and Children (ed) Dublin: The Stationery Office
19.
Zurück zum Zitat Wrieden W, Barton K (2006) Calculation and collation of typical food portion sizes for adults aged 19–64 and older people aged 65 and over. Final Technical Report to the Food Standards Agency. www.foodbase.gov.uk. 11 Jan 2012 Wrieden W, Barton K (2006) Calculation and collation of typical food portion sizes for adults aged 19–64 and older people aged 65 and over. Final Technical Report to the Food Standards Agency. www.​foodbase.​gov.​uk. 11 Jan 2012
20.
Zurück zum Zitat FSA (2002) McCance & Widdowson’s the composition of foods 6th summary edition, R.S.O. Chemistry (ed) Cambridge FSA (2002) McCance & Widdowson’s the composition of foods 6th summary edition, R.S.O. Chemistry (ed) Cambridge
21.
Zurück zum Zitat Black L et al (2011) Development of an on-line Irish food composition database for nutrients. J Food Compost Anal 24(7):1017–1023CrossRef Black L et al (2011) Development of an on-line Irish food composition database for nutrients. J Food Compost Anal 24(7):1017–1023CrossRef
22.
Zurück zum Zitat Drescher LS, Thiele S, Mensink GB (2007) A new index to measure healthy food diversity better reflects a healthy diet than traditional measures. J Nutr 137(3):647–651 Drescher LS, Thiele S, Mensink GB (2007) A new index to measure healthy food diversity better reflects a healthy diet than traditional measures. J Nutr 137(3):647–651
23.
Zurück zum Zitat Claesson MJ et al (2012) Gut microbiota composition correlates with diet and health in the elderly. Nature 488(7410):178–184CrossRef Claesson MJ et al (2012) Gut microbiota composition correlates with diet and health in the elderly. Nature 488(7410):178–184CrossRef
24.
Zurück zum Zitat Atkinson FS, Foster-Powell K, Brand-Miller JC (2008) International tables of glycemic index and glycemic load values: 2008. Diabetes Care 31(12):2281–2283CrossRef Atkinson FS, Foster-Powell K, Brand-Miller JC (2008) International tables of glycemic index and glycemic load values: 2008. Diabetes Care 31(12):2281–2283CrossRef
25.
Zurück zum Zitat Flood A et al (2006) Methodology for adding glycemic load values to the National Cancer Institute Diet History Questionnaire database. J Am Diet Assoc 106(3):393–402CrossRef Flood A et al (2006) Methodology for adding glycemic load values to the National Cancer Institute Diet History Questionnaire database. J Am Diet Assoc 106(3):393–402CrossRef
26.
Zurück zum Zitat Schakel S et al (2008) Development of a glycemic index database for dietary assessment. J Food Compost Anal 21:S50–S55CrossRef Schakel S et al (2008) Development of a glycemic index database for dietary assessment. J Food Compost Anal 21:S50–S55CrossRef
27.
Zurück zum Zitat Burger KN et al (2011) Dietary glycemic load and glycemic index and risk of coronary heart disease and stroke in Dutch men and women: the EPIC-MORGEN study. PLoS One 6(10):e25955CrossRef Burger KN et al (2011) Dietary glycemic load and glycemic index and risk of coronary heart disease and stroke in Dutch men and women: the EPIC-MORGEN study. PLoS One 6(10):e25955CrossRef
28.
Zurück zum Zitat Livesey G et al (2013) Is there a dose-response relation of dietary glycemic load to risk of type 2 diabetes? Meta-analysis of prospective cohort studies. Am J Clin Nutr 97(3):584–596CrossRef Livesey G et al (2013) Is there a dose-response relation of dietary glycemic load to risk of type 2 diabetes? Meta-analysis of prospective cohort studies. Am J Clin Nutr 97(3):584–596CrossRef
29.
Zurück zum Zitat Ledikwe JH et al (2004) Dietary patterns of rural older adults are associated with weight and nutritional status. J Am Geriatr Soc 52(4):589–595CrossRef Ledikwe JH et al (2004) Dietary patterns of rural older adults are associated with weight and nutritional status. J Am Geriatr Soc 52(4):589–595CrossRef
30.
Zurück zum Zitat Pryer JA, Cook A, Shetty P (2001) Identification of groups who report similar patterns of diet among a representative national sample of British adults aged 65 years of age or more. Public Health Nutr 4(03):787–795CrossRef Pryer JA, Cook A, Shetty P (2001) Identification of groups who report similar patterns of diet among a representative national sample of British adults aged 65 years of age or more. Public Health Nutr 4(03):787–795CrossRef
31.
Zurück zum Zitat Hamer M et al (2010) Dietary patterns, assessed from a weighed food record, and survival among elderly participants from the United Kingdom. Eur J Clin Nutr 64(8):853–861CrossRef Hamer M et al (2010) Dietary patterns, assessed from a weighed food record, and survival among elderly participants from the United Kingdom. Eur J Clin Nutr 64(8):853–861CrossRef
32.
Zurück zum Zitat Villegas R et al (2004) Dietary patterns in middle-aged Irish men and women defined by cluster analysis. Public Health Nutr 7(08):1017–1024CrossRef Villegas R et al (2004) Dietary patterns in middle-aged Irish men and women defined by cluster analysis. Public Health Nutr 7(08):1017–1024CrossRef
33.
Zurück zum Zitat Gu Y, Scarmeas N (2011) Dietary patterns in Alzheimer’s disease and cognitive aging. Curr Alzheimer Res 8(5):510CrossRef Gu Y, Scarmeas N (2011) Dietary patterns in Alzheimer’s disease and cognitive aging. Curr Alzheimer Res 8(5):510CrossRef
34.
Zurück zum Zitat Akbaraly TN et al (2009) Education attenuates the association between dietary patterns and cognition. Dement Geriatr Cogn Disord 27(2):147–154CrossRef Akbaraly TN et al (2009) Education attenuates the association between dietary patterns and cognition. Dement Geriatr Cogn Disord 27(2):147–154CrossRef
35.
Zurück zum Zitat Scarmeas N et al (2006) Mediterranean diet and risk for Alzheimer’s disease. Ann Neurol 59(6):912–921CrossRef Scarmeas N et al (2006) Mediterranean diet and risk for Alzheimer’s disease. Ann Neurol 59(6):912–921CrossRef
36.
Zurück zum Zitat Zhong Y et al (2012) Hyperinsulinemia, insulin resistance and cognitive decline in older cohort. Biomed Environ Sci 25(1):8–14 Zhong Y et al (2012) Hyperinsulinemia, insulin resistance and cognitive decline in older cohort. Biomed Environ Sci 25(1):8–14
37.
Zurück zum Zitat Neumann KF et al (2008) Insulin resistance and Alzheimer’s disease: molecular links clinical implications. Curr Alzheimer Res 5(5):438–447CrossRef Neumann KF et al (2008) Insulin resistance and Alzheimer’s disease: molecular links clinical implications. Curr Alzheimer Res 5(5):438–447CrossRef
38.
Zurück zum Zitat Crane PK et al (2013) Glucose levels and risk of dementia. N Engl J Med 369(6):540–548CrossRef Crane PK et al (2013) Glucose levels and risk of dementia. N Engl J Med 369(6):540–548CrossRef
39.
Zurück zum Zitat Ravona-Springer R et al (2012) Changes in glycemic control are associated with changes in cognition in non-diabetic elderly. J Alzheimers Dis 30(2):299–309 Ravona-Springer R et al (2012) Changes in glycemic control are associated with changes in cognition in non-diabetic elderly. J Alzheimers Dis 30(2):299–309
40.
Zurück zum Zitat Lamport DJ et al (2009) Impairments in glucose tolerance can have a negative impact on cognitive function: a systematic research review. Neurosci Biobehav Rev 33(3):394–413CrossRef Lamport DJ et al (2009) Impairments in glucose tolerance can have a negative impact on cognitive function: a systematic research review. Neurosci Biobehav Rev 33(3):394–413CrossRef
41.
Zurück zum Zitat Gregg EW et al (2000) Is diabetes associated with cognitive impairment and cognitive decline among older women? Arch Intern Med 160(2):174CrossRef Gregg EW et al (2000) Is diabetes associated with cognitive impairment and cognitive decline among older women? Arch Intern Med 160(2):174CrossRef
42.
Zurück zum Zitat Strachan MW et al (2011) Cognitive function, dementia and type 2 diabetes mellitus in the elderly. Nat Rev Endocrinol 7(2):108–114CrossRef Strachan MW et al (2011) Cognitive function, dementia and type 2 diabetes mellitus in the elderly. Nat Rev Endocrinol 7(2):108–114CrossRef
43.
Zurück zum Zitat Luchsinger J, Tang M-X, Mayeux R (2007) Glycemic load and risk of Alzheimer’s disease. J Nutr Health Aging 11(3):238–241 Luchsinger J, Tang M-X, Mayeux R (2007) Glycemic load and risk of Alzheimer’s disease. J Nutr Health Aging 11(3):238–241
44.
Zurück zum Zitat O’Bryant SE et al (2008) Detecting dementia with the mini-mental state examination in highly educated individuals. Arch Neurol 65(7):963 O’Bryant SE et al (2008) Detecting dementia with the mini-mental state examination in highly educated individuals. Arch Neurol 65(7):963
45.
Zurück zum Zitat Wengreen HJ et al (2009) Diet quality is associated with better cognitive test performance among aging men and women. J Nutr 139(10):1944–1949CrossRef Wengreen HJ et al (2009) Diet quality is associated with better cognitive test performance among aging men and women. J Nutr 139(10):1944–1949CrossRef
46.
Zurück zum Zitat Eskelinen MH et al (2011) Midlife healthy-diet index and late-life dementia and Alzheimer’s disease. Dement Geriatr Cogn Dis Extra 1(1):103–112CrossRef Eskelinen MH et al (2011) Midlife healthy-diet index and late-life dementia and Alzheimer’s disease. Dement Geriatr Cogn Dis Extra 1(1):103–112CrossRef
47.
Zurück zum Zitat Saka B et al (2010) Malnutrition in the elderly and its relationship with other geriatric syndromes. Clin Nutr 29(6):745–748CrossRef Saka B et al (2010) Malnutrition in the elderly and its relationship with other geriatric syndromes. Clin Nutr 29(6):745–748CrossRef
48.
Zurück zum Zitat Coin A et al (2012) Nutritional predictors of cognitive impairment severity in demented elderly patients: the key role of BMI. J Nutr Health Aging 16(6):553–556CrossRef Coin A et al (2012) Nutritional predictors of cognitive impairment severity in demented elderly patients: the key role of BMI. J Nutr Health Aging 16(6):553–556CrossRef
49.
Zurück zum Zitat El Zoghbi M, Boulos C, Amal AH, et al (2013) Association between cognitive function and nutritional status in elderly: A cross-sectional study in three institutions of Beirut–Lebanon. Geriatr Ment Health Care 1:73–81 El Zoghbi M, Boulos C, Amal AH, et al (2013) Association between cognitive function and nutritional status in elderly: A cross-sectional study in three institutions of Beirut–Lebanon. Geriatr Ment Health Care 1:73–81
50.
51.
Zurück zum Zitat Kimura S (2003) Glycemic carbohydrate and health: background and synopsis of the symposium. Nutr Rev 61:S1–S4CrossRef Kimura S (2003) Glycemic carbohydrate and health: background and synopsis of the symposium. Nutr Rev 61:S1–S4CrossRef
52.
Zurück zum Zitat Jacob RJ et al (2002) Brain glucose levels are elevated in chronically hyperglycemic diabetic rats: no evidence for protective adaptation by the blood brain barrier. Metabolism 51(12):1522–1524CrossRef Jacob RJ et al (2002) Brain glucose levels are elevated in chronically hyperglycemic diabetic rats: no evidence for protective adaptation by the blood brain barrier. Metabolism 51(12):1522–1524CrossRef
53.
Zurück zum Zitat Trone RJ et al (2009) Glycemic index and glycemic load are not associated with brain lesions in the elderly. JNHA 13(2):117–120 Trone RJ et al (2009) Glycemic index and glycemic load are not associated with brain lesions in the elderly. JNHA 13(2):117–120
54.
Zurück zum Zitat Frisoni GB et al (2007) The effect of white matter lesions on cognition in the elderly: small but detectable. Nat Clin Pract Neurol 3(11):620–627CrossRef Frisoni GB et al (2007) The effect of white matter lesions on cognition in the elderly: small but detectable. Nat Clin Pract Neurol 3(11):620–627CrossRef
55.
Zurück zum Zitat Yaffe K et al (2004) Diabetes, impaired fasting glucose, and development of cognitive impairment in older women. Neurology 63(4):658–663CrossRef Yaffe K et al (2004) Diabetes, impaired fasting glucose, and development of cognitive impairment in older women. Neurology 63(4):658–663CrossRef
56.
Zurück zum Zitat Kalmijn S et al (1995) Glucose intolerance, hyperinsulinaemia and cognitive function in a general population of elderly men. Diabetologia 38(9):1096–1102CrossRef Kalmijn S et al (1995) Glucose intolerance, hyperinsulinaemia and cognitive function in a general population of elderly men. Diabetologia 38(9):1096–1102CrossRef
57.
Zurück zum Zitat Gispen WH, Biessels G-J (2000) Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci 23(11):542–549CrossRef Gispen WH, Biessels G-J (2000) Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci 23(11):542–549CrossRef
58.
Zurück zum Zitat Ott V et al (2012) Intranasal administration of insulin to the brain impacts cognitive function and peripheral metabolism. Diabetes Obes Metab 14(3):214–221CrossRef Ott V et al (2012) Intranasal administration of insulin to the brain impacts cognitive function and peripheral metabolism. Diabetes Obes Metab 14(3):214–221CrossRef
59.
Zurück zum Zitat Waldstein SR (2003) The relation of hypertension to cognitive function. Curr Dir Psychol Sci 12(1):9–12CrossRef Waldstein SR (2003) The relation of hypertension to cognitive function. Curr Dir Psychol Sci 12(1):9–12CrossRef
60.
Zurück zum Zitat Plassman BL et al (2010) Systematic review: factors associated with risk for and possible prevention of cognitive decline in later life. Ann Intern Med 153(3):182–193CrossRef Plassman BL et al (2010) Systematic review: factors associated with risk for and possible prevention of cognitive decline in later life. Ann Intern Med 153(3):182–193CrossRef
61.
Zurück zum Zitat Sluijs I et al (2013) Dietary glycemic index, glycemic load, and digestible carbohydrate intake are not associated with risk of type 2 diabetes in eight European countries. J Nutr 143(1):93–99CrossRef Sluijs I et al (2013) Dietary glycemic index, glycemic load, and digestible carbohydrate intake are not associated with risk of type 2 diabetes in eight European countries. J Nutr 143(1):93–99CrossRef
62.
Zurück zum Zitat Dong J-Y et al (2011) Dietary glycaemic index and glycaemic load in relation to the risk of type 2 diabetes: a meta-analysis of prospective cohort studies. Br J Nutr 106(11):1649–1654CrossRef Dong J-Y et al (2011) Dietary glycaemic index and glycaemic load in relation to the risk of type 2 diabetes: a meta-analysis of prospective cohort studies. Br J Nutr 106(11):1649–1654CrossRef
63.
Zurück zum Zitat Reijmer YD et al (2010) Cognitive dysfunction in patients with type 2 diabetes. Diabetes Metabo Res Rev 26(7):507–519CrossRef Reijmer YD et al (2010) Cognitive dysfunction in patients with type 2 diabetes. Diabetes Metabo Res Rev 26(7):507–519CrossRef
64.
Zurück zum Zitat Watson GS, Craft S (2010) The role of insulin resistance in age-related cognitive decline and dementia. In: Biessels GJ, Luchsinger JA (eds) Diabetes Brain. Humana Press, pp 433–457 Watson GS, Craft S (2010) The role of insulin resistance in age-related cognitive decline and dementia. In: Biessels GJ, Luchsinger JA (eds) Diabetes Brain. Humana Press, pp 433–457
65.
Zurück zum Zitat Nabb S, Benton D (2006) The influence on cognition of the interaction between the macro-nutrient content of breakfast and glucose tolerance. Physiol Behav 87(1):16–23CrossRef Nabb S, Benton D (2006) The influence on cognition of the interaction between the macro-nutrient content of breakfast and glucose tolerance. Physiol Behav 87(1):16–23CrossRef
66.
Zurück zum Zitat Papanikolaou Y et al (2006) Better cognitive performance following a low-glycaemic-index compared with a high-glycaemic-index carbohydrate meal in adults with type 2 diabetes. Diabetologia 49(5):855–862CrossRef Papanikolaou Y et al (2006) Better cognitive performance following a low-glycaemic-index compared with a high-glycaemic-index carbohydrate meal in adults with type 2 diabetes. Diabetologia 49(5):855–862CrossRef
67.
Zurück zum Zitat Greenwood CE et al (2003) Carbohydrate-induced memory impairment in adults with type 2 diabetes. Diabetes Care 26(7):1961–1966CrossRef Greenwood CE et al (2003) Carbohydrate-induced memory impairment in adults with type 2 diabetes. Diabetes Care 26(7):1961–1966CrossRef
Metadaten
Titel
Dietary glycaemic load associated with cognitive performance in elderly subjects
verfasst von
Susan E. Power
Eibhlís M. O’Connor
R. Paul Ross
Catherine Stanton
Paul W. O’Toole
Gerald F. Fitzgerald
Ian B. Jeffery
Publikationsdatum
01.06.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Nutrition / Ausgabe 4/2015
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI
https://doi.org/10.1007/s00394-014-0737-5

Weitere Artikel der Ausgabe 4/2015

European Journal of Nutrition 4/2015 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.