Erschienen in:
01.02.2007 | INVITED COMMENTARY
Distal Cholangiocarcinoma: Time for Collaborative Studies
verfasst von:
Saxon Connor, MD
Erschienen in:
World Journal of Surgery
|
Ausgabe 2/2007
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Excerpt
Distal cholangiocarcinoma is a relatively rare malignancy, and hence it represents only a minority of patients undergoing pancreaticoduodenectomy for malignant disease.
1,
2 Accordingly, detailed data identifying important prognostic factors are lacking. In their article Murakami
et al.
3 (DOI: 101007/s00268-006-0224-0) have attempted to identify such factors by analyzing 36 patients who underwent pancreaticoduodenectomy for distal cholangiocarcinoma over a 15-year period, during which time a total of 135 pancreaticoduodenectomies were performed at their institution. The surgery was performed by one unit with a standardized technique. Their conclusion
3 following multivariate analysis of a number of clinicopathologic factors indicates that not only is the presence of nodal metastases an adverse prognostic factor but an increasing number of involved nodes is also associated with poorer long-term outcome. Of particular interest is that of the 11 patients who had more than three lymph nodes involved; none survived more than 2 years, compared to 83% of those who had two or fewer involved nodes. …
