nach oben

Erschienen in:

01.01.2012 | Urogenital

Effectiveness of a three-dimensional dual gradient echo two-point Dixon technique for the characterization of adrenal lesions at 3 Tesla

verfasst von: Daniele Marin, Brian M. Dale, Mustafa R. Bashir, Timothy J. Ziemlewicz, Kristina I. Ringe, Daniel T. Boll, Elmar M. Merkle

Erschienen in: European Radiology | Ausgabe 1/2012

Einloggen, um Zugang zu erhalten

Abstract

Objective

To compare the sensitivity, specificity, and diagnostic accuracy of fat-only datasets reconstructed using a two-point Dixon technique, with corresponding opposed-phase (OP) and in-phase (IP) datasets for characterization of adrenal lesions at 3 Tesla (T).

Methods

Fifty-nine patients (21 male, 38 female) with 66 adrenal lesions (49 adenomas, 17 nonadenomas) underwent 3D dual gradient-echo 3-T adrenal MR imaging with reconstruction of OP/IP and fat/water datasets. Sensitivity, specificity, and diagnostic accuracy were compared between OP/IP datasets, using the signal intensity index (SII), and fat/water datasets, using the fat fraction and fat ratio. Four radiologists qualitatively assessed OP/IP and fat-only datasets for reader confidence in lesion characterization and image quality.

Results

There were significant differences between adenomas and nonadenomas with regard to mean SII, fat fraction, and fat ratio (P < 0.001). There was no significant difference in mean diagnostic accuracy among different evaluation methods using OP/IP and fat/water datasets. Mean readers’ scores for lesion characterization were significantly higher for adenomas than for nonadenomas using OP/IP and fat-only datasets. There was no significant difference between the two datasets regarding mean readers’ scores for image quality.

Conclusion

Fat-only images can readily differentiate adrenal adenomas from nonadenomas, with diagnostic accuracy comparable to OP/IP images.

Key Points

• Incidental adrenal lesions are commonly encountered in radiology practice

• MR has been used to identify lesions giving cause for concern.

• 3T MR provides excellent demonstration of the effects of fat within structures

• Fat-only 3T MR images can readily differentiate adrenal adenomas from nonadenomas

Ma J (2004) Breath-hold water and fat imaging using a dual-echo two-point Dixon technique with an efficient and robust phase-correction algorithm. Magn Reson Med 52:415–419PubMedCrossRef

Ma J, Vu AT, Son JB, Choi H, Hazle JD (2006) Fat-suppressed three-dimensional dual echo Dixon technique for contrast agent enhanced MRI. J Magn Reson Imaging 23:36–41PubMedCrossRef

Hussain HK, Chenevert TL, Londy FJ et al (2005) Hepatic fat fraction: MR imaging for quantitative measurement and display—early experience. Radiology 237:1048–1055PubMedCrossRef

Cassidy FH, Yokoo T, Aganovic L et al (2009) Fatty liver disease: MR imaging techniques for the detection and quantification of liver steatosis. RadioGraphics 29:231–260PubMedCrossRef

Bossuyt PM, Reitsma JB, Bruns DE et al (2003) Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Radiology 226:24–28PubMedCrossRef

Kim JK, Kim SH, Jang YJ et al (2006) Renal angiomyolipoma with minimal fat: differentiation from other neoplasms at double-echo chemical shift FLASH MR imaging. Radiology 239:174–180PubMedCrossRef

Boland GW, Lee MJ, Gazelle GS et al (1998) Characterization of adrenal masses using unenhanced CT: an analysis of the CT literature. AJR Am J Roentgenol 171:201–204PubMed

Reeder SB, McKenzie CA, Pineda AR et al (2007) Water–fat separation with IDEAL gradient-echo imaging. J Magn Reson Imaging 25:644–652PubMedCrossRef

Queiroz-Andrade M, Blasbalg R, Ortega CD et al (2009) MR imaging findings of iron overload. RadioGraphics 29:1575–1589PubMedCrossRef

10.

Fujiyoshi F, Nakajo M, Fukukura Y, Tsuchimochi S (2003) Characterization of adrenal tumors by chemical shift fast low-angle shot MR imaging: comparison of four methods of quantitative evaluation. AJR Am J Roentgenol 180:1649–1657PubMed

11.

Schindera ST, Soher BJ, Delong DM, Dale BM, Merkle EM (2008) Effect of echo time pair selection on quantitative analysis for adrenal tumor characterization with in-phase and opposed-phase MR imaging: initial experience. Radiology 248:140–147PubMedCrossRef

12.

Marin D, Soher BJ, Dale BM, Boll DT, Youngblood RS, Merkle EM (2010) Characterization of adrenal lesions: comparison of 2D and 3D dual gradient-echo MR imaging at 3T—preliminary results. Radiology 254:179–187PubMedCrossRef

13.

Haider MA, Ghai S, Jhaveri K, Lockwood G (2004) Chemical shift MR imaging of hyperattenuating (>10 HU) adrenal masses: does it still have a role? Radiology 231:711–716PubMedCrossRef

14.

Yu H, McKenzie CA, Shimakawa A et al (2007) Multiecho reconstruction for simultaneous water–fat decomposition and T2* estimation. J Magn Reson Imaging 26:1153–1161PubMedCrossRef

15.

Namimoto T, Yamashita Y, Mitsuzaki K et al (2001) Adrenal masses: quantification of fat content with double-echo chemical shift in-phase and opposed-phase FLASH MR images for differentiation of adrenal adenomas. Radiology 218:642–646PubMed

16.

Park BK, Kim CK, Kim B, Lee JH (2007) Comparison of delayed enhanced CT and chemical shift MR for evaluating hyperattenuating incidental adrenal masses. Radiology 243:760–765PubMedCrossRef

17.

Blake MA, Kalra MK, Sweeney AT et al (2006) Distinguishing benign from malignant adrenal masses: multi-detector row CT protocol with 10-minute delay. Radiology 238:578–585PubMedCrossRef

18.

Sangwaiya MJ, Boland GW, Cronin CG, Blake MA, Halpern EF, Hahn PF (2010) Incidental adrenal lesions: accuracy of characterization with contrast-enhanced washout multidetector CT—10-minute delayed imaging protocol revisited in a large patient cohort. Radiology 256:504–510PubMedCrossRef

19.

Song JH, Chaudhry FS, Mayo-Smith WW (2008) The incidental adrenal mass on CT: prevalence of adrenal disease in 1,049 consecutive adrenal masses in patients with no known malignancy. AJR Am J Roentgenol 190:1163–1168PubMedCrossRef

20.

Shinozaki K, Yoshimitsu K, Honda H et al (2001) Metastatic adrenal tumor from clear-cell renal cell carcinoma: a pitfall of chemical shift MR imaging. Abdom Imaging 26:439–442PubMedCrossRef

21.

Outwater EK, Bhatia M, Siegelman ES, Burke MA, Mitchell DG (1997) Lipid in renal clear cell carcinoma: detection on opposed-phase gradient-echo MR images. Radiology 205:103–107PubMed

22.

Schlund JF, Kenney PJ, Brown ED, Ascher SM, Brown JJ, Semelka RC (1995) Adrenocortical carcinoma: MR imaging appearance with current techniques. J Magn Reson Imaging 5:171–174PubMedCrossRef

Titel: Effectiveness of a three-dimensional dual gradient echo two-point Dixon technique for the characterization of adrenal lesions at 3 Tesla
verfasst von: Daniele Marin
Brian M. Dale
Mustafa R. Bashir
Timothy J. Ziemlewicz
Kristina I. Ringe
Daniel T. Boll
Elmar M. Merkle
Publikationsdatum: 01.01.2012
Verlag: Springer-Verlag
Erschienen in: European Radiology / Ausgabe 1/2012
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-011-2244-x

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Effectiveness of a three-dimensional dual gradient echo two-point Dixon technique for the characterization of adrenal lesions at 3 Tesla