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Skeletal Radiology

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21.08.2023 | Case Report

Extranodal Rosai-Dorfman Disease: a rare presentation involving anterior chest wall in a middle-aged female

verfasst von: Abhimanyu Agarwal, Aishwarya Ravindran, James Donahue, Isam-Eldin Eltoum, Mostafa Abozeed

Erschienen in: Skeletal Radiology | Ausgabe 3/2024

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Abstract

Rosai-Dorfman Disease is a rare benign disorder involving overproduction of immune cells, causing swollen lymph nodes and, in rare cases, the sternum. The sternal involvement may cause chest pain and masses. Diagnosis is confirmed through clinical examination, biopsy, and imaging. Treatment options may include surgery, radiation, or steroids. In this case study, we present an unusual example of extranodal Rosai-Dorfman Disease involving the sternum, bilateral clavicles and first three ribs, and pectoral muscle with no associated lymphadenopathy or systemic symptoms in a 57-year-old female. The etiology, pathology, immunohistochemistry, imaging findings, and treatment options of this unique disease are discussed.

Scluster of differentiation

IHC

Immunohistochemistry

OCT2

Octamer binding transcription factor 2

SUV

standardized uptake value

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Titel: Extranodal Rosai-Dorfman Disease: a rare presentation involving anterior chest wall in a middle-aged female
verfasst von: Abhimanyu Agarwal
Aishwarya Ravindran
James Donahue
Isam-Eldin Eltoum
Mostafa Abozeed
Publikationsdatum: 21.08.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Skeletal Radiology / Ausgabe 3/2024
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-023-04427-z

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