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European Journal of Clinical Microbiology & Infectious Diseases

Erschienen in:

01.10.2010 | Brief Report

First outbreak of PVL-positive nonmultiresistant MRSA in a neonatal ICU in Australia: comparison of MALDI-TOF and SNP-plus-binary gene typing

verfasst von: S. Schlebusch, G. R. Price, S. Hinds, C. Nourse, J. M. Schooneveldt, M. H. Tilse, H. G. Liley, T. Wallis, F. Bowling, D. Venter, G. R. Nimmo

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 10/2010

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Abstract

The purpose of this brief report is to describe the first outbreak of a community-associated nonmultiresistant and PVL-positive MRSA strain (CC30) in a neonatal intensive care unit in Australia. The utility of matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF-MS) for microbial typing is compared with single nucleotide polymorphism (SNP) plus binary gene analysis. The composite correlation index analysis of the MALDI-TOF-MS data demonstrated the similar inter-strain relatedness found with the SNP-plus-binary gene typing used to confirm the outbreak. The evolving spread of MRSA emphasizes the importance of surveillance, infection control vigilance and the ongoing investigation of rapid typing methods for MRSA.

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Titel: First outbreak of PVL-positive nonmultiresistant MRSA in a neonatal ICU in Australia: comparison of MALDI-TOF and SNP-plus-binary gene typing
verfasst von: S. Schlebusch
G. R. Price
S. Hinds
C. Nourse
J. M. Schooneveldt
M. H. Tilse
H. G. Liley
T. Wallis
F. Bowling
D. Venter
G. R. Nimmo
Publikationsdatum: 01.10.2010
Verlag: Springer-Verlag
Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 10/2010
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-010-0995-y

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