Skip to main content
Erschienen in: Strahlentherapie und Onkologie 11/2013

01.11.2013 | Original article

Improved cone-beam computed tomography in supine and prone breast radiotherapy

Surface reconstruction, radiation exposure, and clinical workflow

verfasst von: A. De Puysseleyr, Ir., T. Mulliez, M.D., A. Gulyban, M.Sc. Ph.D., E. Bogaert, M.Sc. Ph.D., T. Vercauteren, M.Sc., T. Van Hoof, M.Sc. Ph.D., J. Van de Velde, M.Sc., R. Van Den Broecke, M.D. Ph.D., C. De Wagter, Ir. Ph.D., W. De Neve, M.D. Ph.D.

Erschienen in: Strahlentherapie und Onkologie | Ausgabe 11/2013

Einloggen, um Zugang zu erhalten

Abstract

Background and purpose

Cone-beam computerized tomography (CBCT) enables three-dimensional information of the scanned region and provides soft tissue images with good spatial resolution. Our aim was to optimize image acquisition settings for prone and supine breast radiotherapy with respect to contour accuracy, clinical practicalities, and radiation dose.

Patients and methods

CBCT images were acquired for both prone and supine anthropomorphic phantoms and a female cadaver in supine and prone set-up. CBCT protocols were investigated by altering the tube current, exposure time, range of projection views, field of view (FOV), and starting angle. For clinical practicalities, the frequency of the use of an offset CBCT isocenter was evaluated at 558 205°-CBCTs (37 patients; 13 prone and 24 supine) and 1272 360°-CBCTs (102 patients; 13 prone and 89 supine).

Results

Prone and supine breast CBCT images acquired with a bowtie filter, a small FOV, a range of projection views equaling 180°, a tube current of 20 mA and an exposure time of 32 ms, demonstrated adequate contour accuracy and an elimination of the offset CBCT isocenter procedure, while this occurred in 40.7 % for the old full-rotation protocol. Furthermore a 4.3-fold dose reduction was observed for the Computed Tomography Dose Index (CTDIw) compared to the preset Chest M20 protocol.

Conclusion

The established 180° protocol demonstrated acceptable contour accuracy, eliminated the CBCT isocenter offset procedure and reduced patient radiation exposure.
Literatur
1.
Zurück zum Zitat Jozsef G, DeWyngaert JK, Becker SJ et al (2011) Prospective study of cone-beam computed tomography image-guided radiotherapy for prone accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys 81:568–574PubMedCrossRef Jozsef G, DeWyngaert JK, Becker SJ et al (2011) Prospective study of cone-beam computed tomography image-guided radiotherapy for prone accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys 81:568–574PubMedCrossRef
2.
Zurück zum Zitat Fatunase T, Wang Z, Yoo S et al (2008) Assessment of the residual error in soft tissue setup in patients undergoing partial breast irradiation: results of a prospective study using cone-beam computed tomography. Int J Radiat Oncol Biol Phys 70:1025–1034PubMedCrossRef Fatunase T, Wang Z, Yoo S et al (2008) Assessment of the residual error in soft tissue setup in patients undergoing partial breast irradiation: results of a prospective study using cone-beam computed tomography. Int J Radiat Oncol Biol Phys 70:1025–1034PubMedCrossRef
3.
Zurück zum Zitat Boda-Heggemann J, Lohr F, Wenz F et al (2011) kV cone-beam CT-based IGRT a clinical review. Strahlenther Onkol 187:284–291PubMedCrossRef Boda-Heggemann J, Lohr F, Wenz F et al (2011) kV cone-beam CT-based IGRT a clinical review. Strahlenther Onkol 187:284–291PubMedCrossRef
4.
Zurück zum Zitat Guckenberger M, Ok S, Polat B et al (2010) Toxicity after intensity-modulated, image-guided radiotherapy for prostate cancer. Strahlenther Onkol 186:535–543PubMedCrossRef Guckenberger M, Ok S, Polat B et al (2010) Toxicity after intensity-modulated, image-guided radiotherapy for prostate cancer. Strahlenther Onkol 186:535–543PubMedCrossRef
5.
Zurück zum Zitat Guckenberger M, Meyer J, Wilbert J et al (2007) Precision of image-guided radiotherapy (IGRT) in six degrees of freedom and limitations in clinical practice. Strahlenther Onkol 183:307–313PubMedCrossRef Guckenberger M, Meyer J, Wilbert J et al (2007) Precision of image-guided radiotherapy (IGRT) in six degrees of freedom and limitations in clinical practice. Strahlenther Onkol 183:307–313PubMedCrossRef
6.
Zurück zum Zitat Polat B, Wilbert J, Baier K et al (2007) Nonrigid patient setup errors in the head-and-neck region. Strahlenther Onkol 183:506–511PubMedCrossRef Polat B, Wilbert J, Baier K et al (2007) Nonrigid patient setup errors in the head-and-neck region. Strahlenther Onkol 183:506–511PubMedCrossRef
7.
Zurück zum Zitat Topolnjak R, Sonke JJ, Nijkamp J et al (2010) Breast patient setup error assessment: comparison of electronic portal image devices and cone-beam computed tomography matching results. Int J Radiat Oncol Biol Phys 78:1235–1243PubMedCrossRef Topolnjak R, Sonke JJ, Nijkamp J et al (2010) Breast patient setup error assessment: comparison of electronic portal image devices and cone-beam computed tomography matching results. Int J Radiat Oncol Biol Phys 78:1235–1243PubMedCrossRef
8.
Zurück zum Zitat Stock M, Pasler M, Birkfellner W et al (2009) Image quality and stability of image-guided radiotherapy (IGRT) devices: A comparative study. Radiother Oncol 93:1–7PubMedCrossRef Stock M, Pasler M, Birkfellner W et al (2009) Image quality and stability of image-guided radiotherapy (IGRT) devices: A comparative study. Radiother Oncol 93:1–7PubMedCrossRef
9.
Zurück zum Zitat Oldham M, Letourneau D, Watt L et al (2005) Cone-beam-CT guided radiation therapy: a model for on-line application. Radiother Oncol 75:271–278PubMedCrossRef Oldham M, Letourneau D, Watt L et al (2005) Cone-beam-CT guided radiation therapy: a model for on-line application. Radiother Oncol 75:271–278PubMedCrossRef
10.
Zurück zum Zitat Smitsmans MH, Bois J de, Sonke JJ et al (2005) Automatic prostate localization on cone-beam CT scans for high precision image-guided radiotherapy. Int J Radiat Oncol Biol Phys 63:975–984PubMedCrossRef Smitsmans MH, Bois J de, Sonke JJ et al (2005) Automatic prostate localization on cone-beam CT scans for high precision image-guided radiotherapy. Int J Radiat Oncol Biol Phys 63:975–984PubMedCrossRef
11.
Zurück zum Zitat Kan MW, Leung LH, Wong W, Lam N (2008) Radiation dose from cone beam computed tomography for image-guided radiation therapy. Int J Radiat Oncol Biol Phys 70:272–279PubMedCrossRef Kan MW, Leung LH, Wong W, Lam N (2008) Radiation dose from cone beam computed tomography for image-guided radiation therapy. Int J Radiat Oncol Biol Phys 70:272–279PubMedCrossRef
12.
Zurück zum Zitat De Puysseleyr A, Veldeman L, Bogaert E et al (2011) Optimizing image acquisition settings for cone-beam computed tomography in supine and prone breast radiotherapy. Radiother Oncol 100:227–230CrossRef De Puysseleyr A, Veldeman L, Bogaert E et al (2011) Optimizing image acquisition settings for cone-beam computed tomography in supine and prone breast radiotherapy. Radiother Oncol 100:227–230CrossRef
13.
Zurück zum Zitat Mail N, Moseley DJ, Siewerdsen JH, Jaffray DA (2009) The influence of bowtie filtration on cone-beam CT image quality. Med Phys 36:22–32PubMedCrossRef Mail N, Moseley DJ, Siewerdsen JH, Jaffray DA (2009) The influence of bowtie filtration on cone-beam CT image quality. Med Phys 36:22–32PubMedCrossRef
14.
Zurück zum Zitat Islam MK, Purdie TG, Norrlinger BD et al (2006) Patient dose from kilovoltage cone beam computed tomography imaging in radiation therapy. Med Phys 33:1573–1582PubMedCrossRef Islam MK, Purdie TG, Norrlinger BD et al (2006) Patient dose from kilovoltage cone beam computed tomography imaging in radiation therapy. Med Phys 33:1573–1582PubMedCrossRef
15.
Zurück zum Zitat De Crop A, Bacher K, Van Hoof T et al (2012) Correlation of contrast-detail analysis and clinical image quality assessment in chest radiography with a human cadaver study. Radiology 262:298–304CrossRef De Crop A, Bacher K, Van Hoof T et al (2012) Correlation of contrast-detail analysis and clinical image quality assessment in chest radiography with a human cadaver study. Radiology 262:298–304CrossRef
16.
Zurück zum Zitat Thiel W (1992) The preservation of complete cadavers without loss of natural color. Ann Anat 174:185–195PubMedCrossRef Thiel W (1992) The preservation of complete cadavers without loss of natural color. Ann Anat 174:185–195PubMedCrossRef
17.
Zurück zum Zitat Feldkamp LA, Davis LC, Kress JW (1984) Practical cone-beam algorithm. J Opt Soc Am A 1:612–619CrossRef Feldkamp LA, Davis LC, Kress JW (1984) Practical cone-beam algorithm. J Opt Soc Am A 1:612–619CrossRef
18.
Zurück zum Zitat EU (1999) European Guidelines on Quality Criteria for Computed Tomography Brussels: EU Report No.: EUR 16262 EU (1999) European Guidelines on Quality Criteria for Computed Tomography Brussels: EU Report No.: EUR 16262
19.
Zurück zum Zitat Amer A, Marchant T, Sykes J et al (2007) Imaging doses from the Elekta Synergy X-ray cone beam CT system. Brit J Radiol 80:476–482PubMedCrossRef Amer A, Marchant T, Sykes J et al (2007) Imaging doses from the Elekta Synergy X-ray cone beam CT system. Brit J Radiol 80:476–482PubMedCrossRef
Metadaten
Titel
Improved cone-beam computed tomography in supine and prone breast radiotherapy
Surface reconstruction, radiation exposure, and clinical workflow
verfasst von
A. De Puysseleyr, Ir.
T. Mulliez, M.D.
A. Gulyban, M.Sc. Ph.D.
E. Bogaert, M.Sc. Ph.D.
T. Vercauteren, M.Sc.
T. Van Hoof, M.Sc. Ph.D.
J. Van de Velde, M.Sc.
R. Van Den Broecke, M.D. Ph.D.
C. De Wagter, Ir. Ph.D.
W. De Neve, M.D. Ph.D.
Publikationsdatum
01.11.2013
Verlag
Springer Berlin Heidelberg
Erschienen in
Strahlentherapie und Onkologie / Ausgabe 11/2013
Print ISSN: 0179-7158
Elektronische ISSN: 1439-099X
DOI
https://doi.org/10.1007/s00066-013-0435-x

Weitere Artikel der Ausgabe 11/2013

Strahlentherapie und Onkologie 11/2013 Zur Ausgabe

Mitteilungen der Fachgesellschaften

Mitteilungen der Fachgesellschaften

„Überwältigende“ Evidenz für Tripeltherapie beim metastasierten Prostata-Ca.

22.05.2024 Prostatakarzinom Nachrichten

Patienten mit metastasiertem hormonsensitivem Prostatakarzinom sollten nicht mehr mit einer alleinigen Androgendeprivationstherapie (ADT) behandelt werden, mahnt ein US-Team nach Sichtung der aktuellen Datenlage. Mit einer Tripeltherapie haben die Betroffenen offenbar die besten Überlebenschancen.

So sicher sind Tattoos: Neue Daten zur Risikobewertung

22.05.2024 Melanom Nachrichten

Das größte medizinische Problem bei Tattoos bleiben allergische Reaktionen. Melanome werden dadurch offensichtlich nicht gefördert, die Farbpigmente könnten aber andere Tumoren begünstigen.

CAR-M-Zellen: Warten auf das große Fressen

22.05.2024 Onkologische Immuntherapie Nachrichten

Auch myeloide Immunzellen lassen sich mit chimären Antigenrezeptoren gegen Tumoren ausstatten. Solche CAR-Fresszell-Therapien werden jetzt für solide Tumoren entwickelt. Künftig soll dieser Prozess nicht mehr ex vivo, sondern per mRNA im Körper der Betroffenen erfolgen.

Blutdrucksenkung könnte Uterusmyome verhindern

Frauen mit unbehandelter oder neu auftretender Hypertonie haben ein deutlich erhöhtes Risiko für Uterusmyome. Eine Therapie mit Antihypertensiva geht hingegen mit einer verringerten Inzidenz der gutartigen Tumoren einher.

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.