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Chronobiologie

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Präventionsmedizin und Anti-Aging-Medizin

Zusammenfassung

Gesund leben und gesund altern, dabei geistig und körperlich fit bleiben. – Ein viel gehegter Wunsch, dem man mit der Chronobiologie etwas näherkommen könnte. Denn diese noch junge Wissenschaft untersucht das Zusammenspiel von Zeit, Rhythmizität und Gesundheit. Sie erforscht dabei, wie die biologischen Rhythmen im menschlichen Körper funktionieren und wie diese durch endogene und exogene Vorgänge beeinflusst werden. Schlafen, Essen, Reproduktion, die geistige und körperliche Leistungsfähigkeit, Emotionen: alles physiologische und biochemische Prozesse im menschlichen Organismus, die ihre eigenen Rhythmen haben und verlässlich wie ein Schweizer Uhrwerk sind – vorausgesetzt, sie werden nicht durch externe Einflüsse gestört.

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Literatur

  • Abbott SM, Zee PC (2015) Irregular sleep-wake rhythm disorder. Sleep Med Clin 10(4):517–522

    PubMed  Google Scholar 

  • Adan A, Archer SN, Hidalgo MP, Di Milia L, Natale V, Randler C (2012) Circadian typology: a comprehensive review. Chronobiol Int 29(9):1153–1175

    PubMed  Google Scholar 

  • Asher G, Sassone-Corsi P (2015) Time for food: the intimate interplay between nutrition, metabolism, and the circadian clock. Cell 161(1):84–92

    CAS  PubMed  Google Scholar 

  • Bellet MM, Orozco-Solis R, Sahar S, Eckel-Mahan K, Sassone-Corsi P (2011) The time of metabolism: NAD+, SIRT1, and the circadian clock. Cold Spring Harb Symp Quant Biol 76:31–38

    CAS  PubMed  Google Scholar 

  • Benabu JC, Stoll F, Gonzalez M, Mathelin C (2015) Night work, shift work: Breast cancer risk factor? Gynecol Obstet Fertil 43(12):791–799

    PubMed  Google Scholar 

  • Buxton OM, Marcelli E (2010) Short and long sleep are positively associated with obesity, diabetes, hypertension, and cardiovascular disease among adults in the United States. Soc Sci Med 71(5):1027–1036

    PubMed  Google Scholar 

  • Chang AM, Aeschbach D, Duffy JF, Czeisler CA (2015) Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness. Proc Natl Acad Sci USA 112(4):1232–1237

    CAS  PubMed  Google Scholar 

  • Chen CY, Logan RW, Ma T, Lewis DA, Tseng GC, Sibille E, McClung CA (2016) Effects of aging on circadian patterns of gene expression in the human prefrontal cortex. PNAS 113(1):206–211

    CAS  PubMed  Google Scholar 

  • Dowling GA, Burr RL, Van Someren EJW, Hubbard EM, Luxenberg JS, Mastick J, Cooper BA (2008) Melatonin and bright-light treatment for rest–activity disruption in institutionalized patients with alzheimer’s disease. J Am Geriatr Soc 56(2):239–246

    PubMed  Google Scholar 

  • Dulong S, Ballesta A, Okyar A, Lévi F (2015) Identification of circadian determinants of cancer chronotherapy through in vitro chronopharmacology and mathematical modeling. Mol Cancer Ther 14(9):2154–2164

    CAS  PubMed  Google Scholar 

  • Fauteck JD (2017) Melatonin. Das Geheimnis eines wunderbaren Hormons. Christian Brandstätter, Wien

    Google Scholar 

  • Fauteck JD, Kusztrich I (2017) 90 Mikronährstoffe gegen 900 Krankheiten: Komplette Gesundheit für nur 3 € pro Tag. IGK, Neusiedl am See

    Google Scholar 

  • Fauteck JD, Platzer TM (2016) Die Chronodiät. Satt essen und abnehmen mit der inneren Uhr. Christian Brandstätter, Wien

    Google Scholar 

  • Gan Y, Yang C, Tong X, Sun H, Cong Y, Yin X, Li L, Cao S, Dong X, Gong Y, Shi O, Deng J, Bi H, Lu Z (2015) Shift work and diabetes mellitus: a meta-analysis of observational studies. Occup Environ Med 72(1):72–78

    PubMed  Google Scholar 

  • Gangwisch JE, Heymsfield SB, Boden-Albala B, Buijs RM, Kreier F, Pickering TG, Rundle AG, Zammit GK, Malaspina D (2006) Short sleep duration as a risk factor for hypertension: analyses of the first National Health and Nutrition Examination Survey. Hypertension 47(5):833–839

    CAS  PubMed  Google Scholar 

  • Goel N (2011) Genetics of sleep timing, duration and homeostasis in humans. Sleep Med Clin 6(2):171–182

    PubMed  PubMed Central  Google Scholar 

  • Halberg F (1963) Circadian (about twenty-four-hour) rhythms in experimental medicine. Proc R Soc Med 56(4):253–257

    CAS  PubMed  PubMed Central  Google Scholar 

  • Hardeland R (2013) Chronobiology of melatonin beyond the feedback to the suprachiasmatic nucleus-consequences to melatonin dysfunction. Int J Mol Sci 14(3):5817–5841

    CAS  PubMed  PubMed Central  Google Scholar 

  • Hatori M, Gronfier C, Van Gelder RN, Bernstein PS, Carreras J, Panda S, Marks F, Sliney D, Hunt CE, Hirota T, Furukawa T, Tsubota K (2017) Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies. NPJ Aging Mech Dis 3:9

    PubMed  PubMed Central  Google Scholar 

  • Innominato PF, Roche VP, Palesh OG, Ulusakarya A, Spiegel D, Lévi FA (2014) The circadian timing system in clinical oncology. Ann Med 46(4):191–207

    CAS  PubMed  Google Scholar 

  • International Diabetes Federation. IDF Diabetes Altas. Seventh Edition 2015. www.diabetesatlas.org/component/attachments/?task=download&id=116. Zugegriffen am 26.08.2019

  • James P, Bertrand KA, Hart JE, Schernhammer ES, Tamimi RM, Laden F (2017) Outdoor light at night and breast cancer incidence in the nurses‘ health study II. Environ Health Perspect 125(8):087.010

    Google Scholar 

  • Johnston JD, Ordovás JM, Scheer FA, Turek FW (2016) Circadian rhythms, metabolism, and chrononutrition in rodents and humans. Adv Nutr 7(2):399–406

    CAS  PubMed  PubMed Central  Google Scholar 

  • Julian CG (2017) Epigenomics and human adaptation to high altitude. J Appl Physiol (1985) 123(5):1362–1370. https://doi.org/10.1152/jap.00351.2017

    Article  CAS  Google Scholar 

  • Keller LK, Zöschg S, Grünewald B, Roenneberg T, Schulte-Körne G (2016) Chronotype and depression in adolescents – a review. Z Kinder Jugendpsychiatr Psychother 44(2):113–126

    PubMed  Google Scholar 

  • Kiessling S, Beaulieu-Laroche L, Blum ID, Landgraf D, Welsh DK, Storch KF, Labrecque N, Cermakian N (2017) Enhancing circadian clock function in cancer cells inhibits tumor growth. BMC Biol 15(1):13

    PubMed  PubMed Central  Google Scholar 

  • Kim SW, Jang EC, Kwon SC, Han W, Kang MS, Nam YH, Lee YJ (2016) Night shift work and inflammatory markers in male workers aged 20-39 in a display manufacturing company. Ann Occup Environ Med 28:48

    PubMed  PubMed Central  Google Scholar 

  • Klaffke S, Staedt J (2006) Sundowning and circadian rhythm disorders in dementia. Acta Neurol Belg 106(4):168–175

    CAS  PubMed  Google Scholar 

  • Koch CE, Leinweber B, Drengberg BC, Blaum C, Oster H (2016) Interaction between circadian rhythms and stress. Neurobiol Stress 6:57–67

    PubMed  PubMed Central  Google Scholar 

  • Kolev P, Kumanov P, Caronno A, Fauteck J-D, Stankov BM (2011) Melatonina a rilascio controllato: Nuovi aspetti dell’utilizzo nell’uomo. L’integratore nutrizionale 14(1):15−19

    Google Scholar 

  • Krasselt M, Baerwald C (2017) Sex, symptom severity, and quality of life in rheumatology. Clin. Rev. Allergy Immunol. 2017;26:1214–1221

    Google Scholar 

  • Lévi F (2006) Chronotherapeutics: the relevance of timing in cancer therapy. Cancer Causes Control 17(4):611–621

    PubMed  Google Scholar 

  • Lowden A, Moreno C, Holmbäck U, Lennernäs M, Tucker P (2010) Eating and shift work − effects on habits, metabolism and performance. Scand J Work Environ Health 36(2):150–162

    PubMed  Google Scholar 

  • Mao L, Dauchy RT, Blask DE, Dauchy EM, Slakey LM, Brimer S, Yuan L, Xiang S, Hauch A, Smith K, Frasch T, Belancio VP, Wren MA, Hill SM (2016) Melatonin suppression of aerobic glycolysis (Warburg effect), survival signalling and metastasis in human leiomyosarcoma. J Pineal Res 60(2):167–177

    CAS  PubMed  Google Scholar 

  • Marquié JC, Tucker P, Folkard S, Gentil C, Ansiau D (2015) Chronic effects of shift work on cognition: findings from the VISAT longitudinal study. Occup Environ Med 72(4):258–264

    PubMed  Google Scholar 

  • Martin CK, Bhapkar M, Pittas AG, Pieper CF, Das SK, Williamson DA, Scott T, Redman LM, Stein R, Gilhooly CH, Stewart T, Robinson L, Roberts SB, Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) Phase 2 Study Group (2016) Effect of calorie restriction on mood, quality of life, sleep, and sexual function in healthy nonobese adults: the CALERIE 2 randomized clinical trial. JAMA Intern Med 176(6):743–752

    PubMed  PubMed Central  Google Scholar 

  • Merikanto I, Kronholm E, Peltonen M, Laatikainen T, Vartiainen E, Partonen T (2015) Circadian preference links to depression in general adult population. J Affect Disord 188:143–148

    PubMed  Google Scholar 

  • Ohayon MM, Milesi C (2016) Artificial outdoor nighttime lights associate with altered sleep behavior in the American general population. Sleep 39(6):1311–1320

    PubMed  PubMed Central  Google Scholar 

  • Ortiz-Tudela E, Mteyrek A, Ballesta A, Innominato PF, Lévi F (2013) Cancer chronotherapeutics: experimental, theoretical, and clinical aspects. Handb Exp Pharmacol (217):261–288

    Google Scholar 

  • Oshima T, Yamanaka I, Kumar A, Yamaguchi J, Nishiwaki-Ohkawa T, Muto K, Kawamura R, Hirota T, Yagita K, Irle S, Kay SA, Yoshimura T, Itami K (2015) C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock. Angew Chem Int Ed Eng 54(24):7193–7197

    CAS  Google Scholar 

  • Paolino S, Cutolo M, Pizzorni C (2017) Glucocorticoid management in rheumatoid arthritis: morning or night low dose? Reumatologia 55(4):189–197

    PubMed  PubMed Central  Google Scholar 

  • Prather AA, Janicki-Deverts D, Hall MH, Cohen S (2015) Behaviorally assessed sleep and susceptibility to the common cold. Sleep 38(9):1353–1359

    PubMed  PubMed Central  Google Scholar 

  • Randler C, Rahafar A (2017) Latitude affects Morningness-Eveningness: evidence for the environment hypothesis based on a systematic review. Sci Rep 7:39.976

    Google Scholar 

  • Randler C, Faßl C, Kalb N (2017) From Lark to Owl: developmental changes in morningness-eveningness from new-borns to early adulthood. Sci Rep 7:45.874

    Google Scholar 

  • Rasch B, Born J (2013) About sleep’s role in memory. Physiol Rev 93(2):681–766

    CAS  PubMed  PubMed Central  Google Scholar 

  • Reinberg AE, Lewy H, Smolensky M (2001) The birth of chronobiology: Julien Joseph Virey 1814. Chronobiol Int 18(2):173–186

    CAS  PubMed  Google Scholar 

  • Reiter RJ, Mayo JC, Tan DX, Sainz RM, Alatorre-Jimenez M, Qin L (2016) Melatonin as an antioxidant: under promises but over delivers. J Pineal Res 61(3):253–278

    CAS  PubMed  Google Scholar 

  • Roenneberg T, Merrow M (2016) The circadian clock and human health. Curr Biol 26(10):R432–R443

    CAS  PubMed  Google Scholar 

  • Roenneberg T, Kuehnle T, Juda M, Kantermann T, Allebrandt K, Gordijn M, Merrow M (2007) Epidemiology of the human circadian clock. Sleep Med Rev 11(6):429–438

    PubMed  Google Scholar 

  • Rosales-Corral SA, Acuña-Castroviejo D, Coto-Montes A, Boga JA, Manchester LC, Fuentes-Broto L, Korkmaz A, Ma S, Tan DX, Reiter RJ (2012) Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin. J Pineal Res 52(2):167–202

    CAS  PubMed  Google Scholar 

  • Savaskan E, Ayoub MA, Ravid R, Angeloni D, Fraschini F, Meier F, Eckert A, Müller-Spahn F, Jockers R (2005) Reduced hippocampal MT2 melatonin receptor expression in Alzheimer‘s disease. J Pineal Res 38(1):10–16

    CAS  PubMed  Google Scholar 

  • Savvidis C, Koutsilieris M (2012) Circadian rhythm disruption in cancer biology. Mol Med 18(1):1249–1260

    CAS  PubMed  PubMed Central  Google Scholar 

  • Schmalen I, Reischl S, Wallach T, Klemz R, Grudziecki A, Prabu JR, Benda C, Kramer A, Wolf E (2014) Interaction of circadian clock proteins CRY1 and PER2 is modulated by zinc binding and disulfide bond formation. Cell 157(5):1203–1215

    CAS  PubMed  Google Scholar 

  • Schmidt C, Peigneux P, Cajochen C (2012) Age-related changes in sleep and circadian rhythms: impact on cognitive performance and underlying neuroanatomical networks. Front Neurol 3:118

    PubMed  PubMed Central  Google Scholar 

  • Seifpanahi-Shabani H, Abbasi M, Salehi I, Yousefpour Z, Zamani A (2016) Long-term exposure to extremely low frequency electromagnetic field and melatonin production by blood cells. Int J Occup Environ Med 7(3):193–194

    CAS  PubMed  PubMed Central  Google Scholar 

  • Sipilä JU, Ruuskanen J, Rautava P, Kytö V (2016) Daylight saving time transitions, incidence and in-hospital mortality of ischemic stroke. Neurology 86(16 Suppl):S32.008

    Google Scholar 

  • Stankov BM, Kolev P, Kumanov Ph, Caronno A, Fauteck J-D (2010) Innovation in dietary supplement ingredients: Pharmaceutical techniques and body requirements: faster does not (always) mean better. Time-defined controlled release is crucial for melatonin efficiency in primary sleep disturbances. NutraFoods 13(3):13−18

    Google Scholar 

  • Stevens RG, Brainard GC, Blask DE, Lockley SW, Motta ME (2013) Adverse health effects of nighttime lighting: comments on American Medical Association policy statement. Am J Prev Med 45(3):343–346

    PubMed  Google Scholar 

  • Straub RH, Cutolo M (2016) Glucocorticoids and chronic inflammation. Rheumatology 55(Suppl 2):ii6–ii14

    PubMed  Google Scholar 

  • Touitou Y, Touitou D, Reinberg A (2017) Disruption of adolescents' circadian clock: The vicious circle of media use, exposure to light at night, sleep loss and risk behaviors. J Physiol Paris S0928-4257(17):30.034–30.037

    Google Scholar 

  • Tsaousis I (2010) Circadian preferences and personality traits: A meta-analysis. Eur J Personal 24:356–373

    Google Scholar 

  • Tucker P, Marquié JC, Folkard S, Ansiau D, Esquirol Y (2012) Shiftwork and metabolic dysfunction. Chronobiol Int 29(5):549–555

    PubMed  Google Scholar 

  • Van den Berg JF, Tulen JH, Neven AK, Hofman A, Miedema HM, Witteman JC, Tiemeier H (2007) Sleep duration and hypertension are not associated in the elderly. Hypertension 50(3):585–589

    PubMed  Google Scholar 

  • Vetter C, Scheer FAJL (2017) Circadian biology: uncoupling human body clocks by food timing. Curr Biol 27(13):R656–R658

    CAS  PubMed  Google Scholar 

  • Virey JJ (1814) Éphémérides de la vie humaine, ou recherches sur la révolution journalière et la périodicité de ses phénomènes dans la santé et les maladies. Didot Jeune, Paris

    Google Scholar 

  • Wang H, van Spyk E, Liu Q, Geyfman M, Salmans ML, Kumar V, Ihler A, Li N, Takahashi JS, Andersen B (2017) Time-restricted feeding shifts the skin circadian clock and alters UVB-induced DNA damage. Cell Rep 20(5):1061–1072

    CAS  PubMed  PubMed Central  Google Scholar 

  • Wehrens SMT, Christou S, Isherwood C, Middleton B, Gibbs MA, Archer SN, Skene DJ, Johnston JD (2017) Meal timing regulates the human circadian system. Curr Biol 27(12):1768–1775.e3

    CAS  PubMed  PubMed Central  Google Scholar 

  • Westermann J, Lange T, Textor J, Born J (2015) System consolidation during sleep − a common principle underlying psychological and immunological memory formation. Trends Neurosci 38(10):585–597

    CAS  PubMed  Google Scholar 

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  1. Kalletal, Deutschland

    Jan-Dirk Fauteck

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  1. Jan-Dirk Fauteck
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Correspondence to Jan-Dirk Fauteck .

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  1. Gynäkologische Praxis, Metropol Medical Center, Nürnberg, Deutschland

    Bernd Kleine-Gunk

  2. Ulm, Deutschland

    Alfred Wolf

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Fauteck, JD. (2022). Chronobiologie . In: Kleine-Gunk, B., Wolf, A. (eds) Präventionsmedizin und Anti-Aging-Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-61417-4_13

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