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Pulmonary hypertension and dexfenfluramine

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Abstract

Appetite suppressants, including aminorex and fenfluramine, have been associated with pulmonary hypertension ever since the well-known outbreak of primary pulmonary hypertension in Europe after treatment with aminorex. The usage of a new anorectic agent, dexfenfluramine, has recently increased dramatically in developed countries. We report 2 new cases of lethal pulmonary hypertension associated with the use of dexfenfluramine.

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Cacoub, P., Piette, J.C., Godeau, P. et al. Pulmonary hypertension and dexfenfluramine. Eur J Clin Pharmacol 48, 81–83 (1995). https://doi.org/10.1007/BF00202179

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  • DOI: https://doi.org/10.1007/BF00202179

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