nach oben

Erschienen in:

01.10.2015 | Meta-Analysis

Excessive gestational weight gain prior to glucose screening and the risk of gestational diabetes: a meta-analysis

verfasst von: Stefanie Brunner, Lynne Stecher, Stephanie Ziebarth, Ina Nehring, Sheryl L. Rifas-Shiman, Christine Sommer, Hans Hauner, Rüdiger von Kries

Erschienen in: Diabetologia | Ausgabe 10/2015

Einloggen, um Zugang zu erhalten

Abstract

Aims/hypothesis

Excessive gestational weight gain (GWG) may be a risk factor for gestational diabetes mellitus (GDM). We aimed to study the association between excessive GWG (defined according to Institute of Medicine recommendations) prior to GDM screening, and GDM.

Methods

We systematically searched four electronic databases from 1990 until September 2014 for observational studies published in English or German that reported an association between excessive GWG and GDM as the outcome. Random effects meta-analyses were performed to provide a pooled estimate of the OR comparing the risk of GDM in women with and without excessive GWG.

Results

A total of eight studies involving 13,748 participants were included. The pooled analysis of unadjusted OR yielded a summary OR of 1.40 (95% CI 1.21, 1.61; p < 0.001) with low between-study heterogeneity (I ² = 16.7%). A sensitivity analysis based on four studies reporting adjusted effect estimates revealed similar results (OR 1.42; 95% CI 1.20, 1.68; p < 0.001; I ² = 0%). No evidence was found that the effect of GWG on GDM differs depending on maternal pre-pregnancy BMI category. A funnel plot did not indicate substantial publication bias.

Conclusions/interpretation

Avoiding excessive weight gain in pregnancy prior to the GDM screening test may be a potential strategy to reduce GDM risk.

Meta-analysis registration

www.crd.york.ac.uk/PROSPERO CRD42014008802

Nur mit Berechtigung zugänglich

Ferrara A (2007) Increasing prevalence of gestational diabetes mellitus: a public health perspective. Diabetes Care 30(Suppl 2):S141–S146CrossRefPubMed

Jovanovic L, Pettitt DJ (2001) Gestational diabetes mellitus. JAMA 286:2516–2518CrossRefPubMed

Nehring I, Chmitorz A, Reulen H, von Kries R, Ensenauer R (2013) Gestational diabetes predicts the risk of childhood overweight and abdominal circumference independent of maternal obesity. Diabet Med 30:1449–1456CrossRefPubMed

Kim C, Newton KM, Knopp RH (2002) Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care 25:1862–1868CrossRefPubMed

Dabelea D, Crume T (2011) Maternal environment and the transgenerational cycle of obesity and diabetes. Diabetes 60:1849–1855PubMedCentralCrossRefPubMed

Siega-Riz AM, Viswanathan M, Moos MK et al (2009) A systematic review of outcomes of maternal weight gain according to the Institute of Medicine recommendations: birthweight, fetal growth, and postpartum weight retention. Am J Obstet Gynecol 201(339):e331–314

Beyerlein A, Lack N, von Kries R (2010) Within-population average ranges compared with Institute of Medicine recommendations for gestational weight gain. Obstet Gynecol 116:1111–1118CrossRefPubMed

Nehring I, Lehmann S, von Kries R (2013) Gestational weight gain in accordance to the IOM/NRC criteria and the risk for childhood overweight: a meta-analysis. Pediatr Obes 8:218–224CrossRefPubMed

Nehring I, Schmoll S, Beyerlein A, Hauner H, von Kries R (2011) Gestational weight gain and long-term postpartum weight retention: a meta-analysis. Am J Clin Nutr 94:1225–1231CrossRefPubMed

10.

Institute of Medicine (US) and National Research Council (US) Committee to Reexamine IOM Pregnancy Weight Guidelines, Rasmussen KM, Yaktine AL (eds) (2009) Weight gain during pregnancy: reexamining the guidelines. National Academies Press, Washington DC

11.

Nohr EA, Vaeth M, Baker JL, Sorensen T, Olsen J, Rasmussen KM (2008) Combined associations of prepregnancy body mass index and gestational weight gain with the outcome of pregnancy. Am J Clin Nutr 87:1750–1759PubMed

12.

Catalano PM, Roman NM, Tyzbir ED, Merritt AO, Driscoll P, Amini SB (1993) Weight gain in women with gestational diabetes. Obstet Gynecol 81:523–528PubMed

13.

Morisset AS, Tchernof A, Dube MC, Veillette J, Weisnagel SJ, Robitaille J (2011) Weight gain measures in women with gestational diabetes mellitus. J Women’s Health 20:375–380CrossRef

14.

Gaillard R, Durmus B, Hofman A, Mackenbach JP, Steegers EA, Jaddoe VW (2013) Risk factors and outcomes of maternal obesity and excessive weight gain during pregnancy. Obesity (Silver Spring) 21:1046–1055CrossRef

15.

Hedderson MM, Gunderson EP, Ferrara A (2010) Gestational weight gain and risk of gestational diabetes mellitus. Obstet Gynecol 115:597–604PubMedCentralCrossRefPubMed

16.

Liu Z, Ao D, Yang H, Wang Y (2014) Gestational weight gain and risk of gestational diabetes mellitus among Chinese women. Chin Med J (Engl) 127:1255–1260

17.

Sommer C, Morkrid K, Jenum AK, Sletner L, Mosdol A, Birkeland KI (2014) Weight gain, total fat gain and regional fat gain during pregnancy and the association with gestational diabetes: a population-based cohort study. Int J Obes 38:76–81CrossRef

18.

Stroup DF, Berlin JA, Morton SC et al (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 283:2008–2012CrossRefPubMed

19.

Gibson KS, Waters TP, Catalano PM (2012) Maternal weight gain in women who develop gestational diabetes mellitus. Obstet Gynecol 119:560–565CrossRefPubMed

20.

Harrison CL, Lombard CB, Teede HJ (2012) Understanding health behaviours in a cohort of pregnant women at risk of gestational diabetes mellitus: an observational study. BJOG: Int J Obstet Gynaecol 119:731–738CrossRef

21.

Saldana TM, Siega-Riz AM, Adair LS, Suchindran C (2006) The relationship between pregnancy weight gain and glucose tolerance status among black and white women in central North Carolina. Am J Obstet Gynecol 195:1629–1635CrossRefPubMed

22.

Herring SJ, Oken E, Rifas-Shiman SL et al (2009) Weight gain in pregnancy and risk of maternal hyperglycemia. Am J Obstet Gynecol 201:61.e61–61.e67CrossRef

23.

Gaillard R, Durmus B, Hofman A, MacKenbach J, Steegers E, Jaddoe V (2012) Risk factors and outcomes of maternal obesity and excessive weight gain during pregnancy. Pregnancy Hypertens 2(3):186PubMed

24.

Rajput R, Yadav Y, Nanda S, Rajput M (2013) Prevalence of gestational diabetes mellitus & associated risk factors at a tertiary care hospital in Haryana. Indian J Med Res 137:728–733PubMedCentralPubMed

25.

Far MA, Ziaei S, Kazemnejad A (2012) The impact of maternal age, pre-pregnancy body mass index, weight gain and parity on glucose challenge test (GCT). Int J Fertil Steril 5:207–210

26.

Da Ros Wendland EM, Duncan BB, Belizan JM, Vigo A, Schmidt MI (2008) Gestational diabetes and pre-eclampsia: common antecedents? Arq Bras Endocrinol Metabol 52:975–984CrossRef

27.

Kieffer EC, Carman WJ, Gillespie BW, Nolan GH, Worley SE, Guzman JR (2001) Obesity and gestational diabetes among African-American women and Latinas in Detroit: implications for disparities in women’s health. J Am Med Womens Assoc (1972) 56:181–187, 196

28.

Jang HC, Min HK, Lee HK, Cho NH, Metzger BE (1998) Short stature in Korean women: a contribution to the multifactorial predisposition to gestational diabetes mellitus. Diabetologia 41:778–783CrossRefPubMed

29.

Yang XL, Hsu-Hage B, Zhang H et al (2002) Gestational diabetes mellitus in women of single gravidity in Tianjin City, China. Diabetes Care 25:847–851CrossRefPubMed

30.

Di Cianni G, Volpe L, Lencioni C et al (2003) Prevalence and risk factors for gestational diabetes assessed by universal screening. Diabetes Res Clin Pract 62:131–137CrossRefPubMed

31.

Roseman JM, Go RCP, Perkins LL et al (1991) Gestational diabetes mellitus among African-American women. Diabetes Metab Rev 7:93–104CrossRefPubMed

32.

Jackson R, Ameratunga S, Broad J et al (2006) The GATE frame: critical appraisal with pictures. Evid Based Med 11:35–38CrossRefPubMed

33.

Baci Y, Ustuner I, Keskin HL, Ersoy R, Avsar AF (2013) Effect of maternal obesity and weight gain on gestational diabetes mellitus. Gynecol Endocrinol 29:133–136CrossRefPubMed

34.

Carreno CA, Clifton RG, Hauth JC et al (2012) Excessive early gestational weight gain and risk of gestational diabetes mellitus in nulliparous women. Obstet Gynecol 119:1227–1233PubMedCentralCrossRefPubMed

35.

Park S, Kim MH, Kim SH (2014) Early gestational weight gains within current recommendations result in increased risk of gestational diabetes mellitus among Korean women. Diabetes Metab Res Rev 30:716–725CrossRefPubMed

36.

Ruifrok AE, van Poppel MN, van Wely M et al (2014) Association between weight gain during pregnancy and pregnancy outcomes after dietary and lifestyle interventions: a meta-analysis. Am J Perinatol 31:353–364PubMed

37.

Tovar A, Must A, Bermudez OI, Hyatt RR, Chasan-Taber L (2009) The impact of gestational weight gain and diet on abnormal glucose tolerance during pregnancy in Hispanic women. Matern Child Health J 13:520–530PubMedCentralCrossRefPubMed

38.

Committee on Nutritional Status During Pregnancy and Lactation, Institute of Medicine (1990) Nutrition during pregnancy: part I weight gain: part II nutrient supplements (1990). National Academy of Sciences, Washington DC

39.

van Raaij JM, Peek ME, Vermaat-Miedema SH, Schonk CM, Hautvast JG (1988) New equations for estimating body fat mass in pregnancy from body density or total body water. Am J Clin Nutr 48:24–29PubMed

40.

Oken E, Taveras EM, Kleinman KP, Rich-Edwards JW, Gillman MW (2007) Gestational weight gain and child adiposity at age 3 years. Am J Obstet Gynecol 196(322):e321–e328

41.

Shin D, Chung H, Weatherspoon L, Song WO (2014) Validity of prepregnancy weight status estimated from self-reported height and weight. Matern Child Health J 18:1667–1674CrossRefPubMed

42.

Knabl J, Riedel C, Gmach J et al (2014) Prediction of excessive gestational weight gain from week-specific cutoff values: a cohort study. J Perinatol 34:351–356CrossRefPubMed

43.

Oteng-Ntim E, Varma R, Croker H, Poston L, Doyle P (2012) Lifestyle interventions for overweight and obese pregnant women to improve pregnancy outcome: systematic review and meta-analysis. BMC Med 10:47PubMedCentralCrossRefPubMed

44.

Tanentsapf I, Heitmann BL, Adegboye AR (2011) Systematic review of clinical trials on dietary interventions to prevent excessive weight gain during pregnancy among normal weight, overweight and obese women. BMC Pregnancy Childbirth 11:81PubMedCentralCrossRefPubMed

45.

Thangaratinam S, Rogozinska E, Jolly K et al (2012) Effects of interventions in pregnancy on maternal weight and obstetric outcomes: meta-analysis of randomised evidence. BMJ 344:e2088PubMedCentralCrossRefPubMed

46.

Rauh K, Gabriel E, Kerschbaum E et al (2013) Safety and efficacy of a lifestyle intervention for pregnant women to prevent excessive maternal weight gain: a cluster-randomized controlled trial. BMC Pregnancy Childbirth 13:151PubMedCentralCrossRefPubMed

Titel: Excessive gestational weight gain prior to glucose screening and the risk of gestational diabetes: a meta-analysis
verfasst von: Stefanie Brunner
Lynne Stecher
Stephanie Ziebarth
Ina Nehring
Sheryl L. Rifas-Shiman
Christine Sommer
Hans Hauner
Rüdiger von Kries
Publikationsdatum: 01.10.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Diabetologia / Ausgabe 10/2015
Print ISSN: 0012-186X
Elektronische ISSN: 1432-0428
DOI: https://doi.org/10.1007/s00125-015-3686-5

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Excessive gestational weight gain prior to glucose screening and the risk of gestational diabetes: a meta-analysis