Skip to main content
Erschienen in: Intensive Care Medicine 4/2009

01.04.2009 | Original

Is helmet CPAP first line pre-hospital treatment of presumed severe acute pulmonary edema?

verfasst von: Giuseppe Foti, Fabio Sangalli, Lorenzo Berra, Stefano Sironi, Marco Cazzaniga, Gian Piera Rossi, Giacomo Bellani, Antonio Pesenti

Erschienen in: Intensive Care Medicine | Ausgabe 4/2009

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Non-invasive continuous positive airway pressure (CPAP) is effective in reducing intubation rate and mortality of patient with acute cardiogenic pulmonary edema (ACPE). We report our experience on pre-hospital application of CPAP by helmet as an adjunct to medical therapy or as a stand alone procedure in patient with presumed ACPE.

Methods

In pre-hospital treatment of 62 patients with presumed ACPE, CPAP was added to standard medical treatment while in another 59 patients, CPAP was used as a sole therapy.

Results

Helmet CPAP was feasible in all patients. No patient required pre-hospital intubation. In both groups, CPAP significantly improved oxygenation (SpO2 went from 79 ± 12 to 97 ± 3% and from 81 ± 13 to 98 ± 3%), reduced respiratory rate (from 26 ± 4 to 21 ± 3 bpm and from 30 ± 9 to 22 ± 8 bpm) and improved hemodynamics, with a more pronounced decrease in blood pressure in the group with medical treatment than in the one without it. In the two cohorts, four and five patients were, respectively, intubated in Emergency Department and 11 and 9 eventually died.

Conclusions

Helmet CPAP is feasible, efficient and safe in pre-hospital treatment of presumed ACPE. A significant improvement of physiological variables was observed also in the group treated with CPAP in the absence of a drug therapy. We propose helmet CPAP as first line pre-hospital treatment of presumed severe ACPE.
Literatur
1.
Zurück zum Zitat Stiell IG, Spaite DW, Field B, Nesbitt LP, Munkley D, Maloney J, Dreyer J, Toohey LL, Campeau T, Dagnone E, Lyver M, Wells GA (2007) Advanced life support for out-of-hospital respiratory distress. N Engl J Med 356:2156–2164PubMedCrossRef Stiell IG, Spaite DW, Field B, Nesbitt LP, Munkley D, Maloney J, Dreyer J, Toohey LL, Campeau T, Dagnone E, Lyver M, Wells GA (2007) Advanced life support for out-of-hospital respiratory distress. N Engl J Med 356:2156–2164PubMedCrossRef
2.
Zurück zum Zitat Rasanen J, Heikkila J, Downs J, Nikki P, Vaisanen I, Viitanen A (1985) Continuous positive airway pressure by face mask in acute cardiogenic pulmonary edema. Am J Cardiol 55:296–300PubMedCrossRef Rasanen J, Heikkila J, Downs J, Nikki P, Vaisanen I, Viitanen A (1985) Continuous positive airway pressure by face mask in acute cardiogenic pulmonary edema. Am J Cardiol 55:296–300PubMedCrossRef
3.
Zurück zum Zitat Bersten AD, Holt AW, Vedig AE, Skowronski GA, Baggoley CJ (1991) Treatment of severe cardiogenic pulmonary edema with continuous positive airway pressure delivered by face mask. N Engl J Med 325:1825–1830PubMed Bersten AD, Holt AW, Vedig AE, Skowronski GA, Baggoley CJ (1991) Treatment of severe cardiogenic pulmonary edema with continuous positive airway pressure delivered by face mask. N Engl J Med 325:1825–1830PubMed
4.
Zurück zum Zitat Crane SD, Elliott MW, Gilligan P, Richards K, Gray AJ (2004) Randomised controlled comparison of continuous positive airways pressure, bilevel non-invasive ventilation, and standard treatment in emergency department patients with acute cardiogenic pulmonary oedema. Emerg Med J 21:155–161PubMedCrossRef Crane SD, Elliott MW, Gilligan P, Richards K, Gray AJ (2004) Randomised controlled comparison of continuous positive airways pressure, bilevel non-invasive ventilation, and standard treatment in emergency department patients with acute cardiogenic pulmonary oedema. Emerg Med J 21:155–161PubMedCrossRef
5.
Zurück zum Zitat Lin M, Yang YF, Chiang HT, Chang MS, Chiang BN, Cheitlin MD (1995) Reappraisal of continuous positive airway pressure therapy in acute cardiogenic pulmonary edema. Short-term results and long-term follow-up. Chest 107:1379–1386PubMedCrossRef Lin M, Yang YF, Chiang HT, Chang MS, Chiang BN, Cheitlin MD (1995) Reappraisal of continuous positive airway pressure therapy in acute cardiogenic pulmonary edema. Short-term results and long-term follow-up. Chest 107:1379–1386PubMedCrossRef
6.
Zurück zum Zitat Masip J, Roque M, Sanchez B, Fernandez R, Subirana M, Exposito JA (2005) Noninvasive ventilation in acute cardiogenic pulmonary edema: systematic review and meta-analysis. JAMA 294:3124–3130PubMedCrossRef Masip J, Roque M, Sanchez B, Fernandez R, Subirana M, Exposito JA (2005) Noninvasive ventilation in acute cardiogenic pulmonary edema: systematic review and meta-analysis. JAMA 294:3124–3130PubMedCrossRef
7.
Zurück zum Zitat Nava S, Carbone G, DiBattista N, Bellone A, Baiardi P, Cosentini R, Marenco M, Giostra F, Borasi G, Groff P (2003) Noninvasive ventilation in cardiogenic pulmonary edema: a multicenter randomized trial. Am J Respir Crit Care Med 168:1432–1437PubMedCrossRef Nava S, Carbone G, DiBattista N, Bellone A, Baiardi P, Cosentini R, Marenco M, Giostra F, Borasi G, Groff P (2003) Noninvasive ventilation in cardiogenic pulmonary edema: a multicenter randomized trial. Am J Respir Crit Care Med 168:1432–1437PubMedCrossRef
8.
Zurück zum Zitat Pang D, Keenan SP, Cook DJ, Sibbald WJ (1998) The effect of positive pressure airway support on mortality and the need for intubation in cardiogenic pulmonary edema: a systematic review. Chest 114:1185–1192PubMedCrossRef Pang D, Keenan SP, Cook DJ, Sibbald WJ (1998) The effect of positive pressure airway support on mortality and the need for intubation in cardiogenic pulmonary edema: a systematic review. Chest 114:1185–1192PubMedCrossRef
9.
Zurück zum Zitat Park M, Sangean MC, Volpe Mde S, Feltrim MI, Nozawa E, Leite PF, Passos Amato MB, Lorenzi-Filho G (2004) Randomized, prospective trial of oxygen, continuous positive airway pressure, and bilevel positive airway pressure by face mask in acute cardiogenic pulmonary edema. Crit Care Med 32:2407–2415PubMedCrossRef Park M, Sangean MC, Volpe Mde S, Feltrim MI, Nozawa E, Leite PF, Passos Amato MB, Lorenzi-Filho G (2004) Randomized, prospective trial of oxygen, continuous positive airway pressure, and bilevel positive airway pressure by face mask in acute cardiogenic pulmonary edema. Crit Care Med 32:2407–2415PubMedCrossRef
10.
Zurück zum Zitat Peter JV, Moran JL, Phillips-Hughes J, Graham P, Bersten AD (2006) Effect of non-invasive positive pressure ventilation (NIPPV) on mortality in patients with acute cardiogenic pulmonary oedema: a meta-analysis. Lancet 367:1155–1163PubMedCrossRef Peter JV, Moran JL, Phillips-Hughes J, Graham P, Bersten AD (2006) Effect of non-invasive positive pressure ventilation (NIPPV) on mortality in patients with acute cardiogenic pulmonary oedema: a meta-analysis. Lancet 367:1155–1163PubMedCrossRef
11.
Zurück zum Zitat Gray A, Goodacre S, Newby DE, Masson M, Sampson F, Nicholl J (2008) Noninvasive ventilation in acute cardiogenic pulmonary edema. N Engl J Med 359:142–151PubMedCrossRef Gray A, Goodacre S, Newby DE, Masson M, Sampson F, Nicholl J (2008) Noninvasive ventilation in acute cardiogenic pulmonary edema. N Engl J Med 359:142–151PubMedCrossRef
12.
Zurück zum Zitat Plaisance P, Pirracchio R, Berton C, Vicaut E, Payen D (2007) A randomized study of out-of-hospital continuous positive airway pressure for acute cardiogenic pulmonary oedema: physiological and clinical effects. Eur Heart J 28:2895–2901PubMedCrossRef Plaisance P, Pirracchio R, Berton C, Vicaut E, Payen D (2007) A randomized study of out-of-hospital continuous positive airway pressure for acute cardiogenic pulmonary oedema: physiological and clinical effects. Eur Heart J 28:2895–2901PubMedCrossRef
13.
Zurück zum Zitat Mehta S, Hill NS (2001) Noninvasive ventilation. Am J Respir Crit Care Med 163:540–577PubMed Mehta S, Hill NS (2001) Noninvasive ventilation. Am J Respir Crit Care Med 163:540–577PubMed
14.
Zurück zum Zitat Principi T, Pantanetti S, Catani F, Elisei D, Gabbanelli V, Pelaia P, Leoni P (2004) Noninvasive continuous positive airway pressure delivered by helmet in hematological malignancy patients with hypoxemic acute respiratory failure. Intensive Care Med 30:147–150 Epub 2003 Oct 2031PubMedCrossRef Principi T, Pantanetti S, Catani F, Elisei D, Gabbanelli V, Pelaia P, Leoni P (2004) Noninvasive continuous positive airway pressure delivered by helmet in hematological malignancy patients with hypoxemic acute respiratory failure. Intensive Care Med 30:147–150 Epub 2003 Oct 2031PubMedCrossRef
15.
Zurück zum Zitat Tonnelier JM, Prat G, Nowak E, Goetghebeur D, Renault A, Boles JM, L’Her E (2003) Noninvasive continuous positive airway pressure ventilation using a new helmet interface: a case-control prospective pilot study. Intensive Care Med 29:2077–2080PubMedCrossRef Tonnelier JM, Prat G, Nowak E, Goetghebeur D, Renault A, Boles JM, L’Her E (2003) Noninvasive continuous positive airway pressure ventilation using a new helmet interface: a case-control prospective pilot study. Intensive Care Med 29:2077–2080PubMedCrossRef
16.
Zurück zum Zitat Patroniti N, Foti G, Manfio A, Coppo A, Bellani G, Pesenti A (2003) Head helmet versus face mask for non-invasive continuous positive airway pressure: a physiological study. Intensive Care Med 29:1680–1687PubMedCrossRef Patroniti N, Foti G, Manfio A, Coppo A, Bellani G, Pesenti A (2003) Head helmet versus face mask for non-invasive continuous positive airway pressure: a physiological study. Intensive Care Med 29:1680–1687PubMedCrossRef
17.
Zurück zum Zitat Delclaux C, L’Her E, Alberti C, Mancebo J, Abroug F, Conti G, Guerin C, Schortgen F, Lefort Y, Antonelli M, Lepage E, Lemaire F, Brochard L (2000) Treatment of acute hypoxemic nonhypercapnic respiratory insufficiency with continuous positive airway pressure delivered by a face mask: a randomized controlled trial. JAMA 284:2352–2360PubMedCrossRef Delclaux C, L’Her E, Alberti C, Mancebo J, Abroug F, Conti G, Guerin C, Schortgen F, Lefort Y, Antonelli M, Lepage E, Lemaire F, Brochard L (2000) Treatment of acute hypoxemic nonhypercapnic respiratory insufficiency with continuous positive airway pressure delivered by a face mask: a randomized controlled trial. JAMA 284:2352–2360PubMedCrossRef
18.
Zurück zum Zitat Squadrone V, Coha M, Cerutti E, Schellino MM, Biolino P, Occella P, Belloni G, Vilianis G, Fiore G, Cavallo F, Ranieri VM (2005) Continuous positive airway pressure for treatment of postoperative hypoxemia: a randomized controlled trial. JAMA 293:589–595PubMedCrossRef Squadrone V, Coha M, Cerutti E, Schellino MM, Biolino P, Occella P, Belloni G, Vilianis G, Fiore G, Cavallo F, Ranieri VM (2005) Continuous positive airway pressure for treatment of postoperative hypoxemia: a randomized controlled trial. JAMA 293:589–595PubMedCrossRef
19.
Zurück zum Zitat Bellani G, Patroniti N, Greco M, Foti G, Pesenti A (2008) The use of helmets to deliver non-invasive continuous positive airway pressure in hypoxemic acute respiratory failure. Minerva Anestesiol 74:651–656PubMed Bellani G, Patroniti N, Greco M, Foti G, Pesenti A (2008) The use of helmets to deliver non-invasive continuous positive airway pressure in hypoxemic acute respiratory failure. Minerva Anestesiol 74:651–656PubMed
20.
Zurück zum Zitat Kosowsky JM, Stephanides SL, Branson RD, Sayre MR (2001) Prehospital use of continuous positive airway pressure (CPAP) for presumed pulmonary edema: a preliminary case series. Prehosp Emerg Care 5:190–196PubMedCrossRef Kosowsky JM, Stephanides SL, Branson RD, Sayre MR (2001) Prehospital use of continuous positive airway pressure (CPAP) for presumed pulmonary edema: a preliminary case series. Prehosp Emerg Care 5:190–196PubMedCrossRef
21.
Zurück zum Zitat Templier F, Dolveck F, Baer M, Chauvin M, Fletcher D (2003) ‘Boussignac’ continuous positive airway pressure system: practical use in a prehospital medical care unit. Eur J Emerg Med 10:87–93PubMedCrossRef Templier F, Dolveck F, Baer M, Chauvin M, Fletcher D (2003) ‘Boussignac’ continuous positive airway pressure system: practical use in a prehospital medical care unit. Eur J Emerg Med 10:87–93PubMedCrossRef
22.
Zurück zum Zitat Taccone P, Hess D, Caironi P, Bigatello LM (2004) Continuous positive airway pressure delivered with a “helmet”: effects on carbon dioxide rebreathing. Crit Care Med 32:2090–2096PubMedCrossRef Taccone P, Hess D, Caironi P, Bigatello LM (2004) Continuous positive airway pressure delivered with a “helmet”: effects on carbon dioxide rebreathing. Crit Care Med 32:2090–2096PubMedCrossRef
23.
Zurück zum Zitat Pelosi P, Chiumello D, Calvi E, Taccone P, Bottino N, Panigada M, Cadringher P, Gattinoni L (2001) Effects of different continuous positive airway pressure devices and periodic hyperinflations on respiratory function. Crit Care Med 29:1683–1689PubMedCrossRef Pelosi P, Chiumello D, Calvi E, Taccone P, Bottino N, Panigada M, Cadringher P, Gattinoni L (2001) Effects of different continuous positive airway pressure devices and periodic hyperinflations on respiratory function. Crit Care Med 29:1683–1689PubMedCrossRef
24.
Zurück zum Zitat Villa F, Cereda M, Colombo E, Foti G, Pesenti A (1999) Evaluation of four noninvasive CPAP systems. Intensive Care Med S6:A246 Villa F, Cereda M, Colombo E, Foti G, Pesenti A (1999) Evaluation of four noninvasive CPAP systems. Intensive Care Med S6:A246
25.
Zurück zum Zitat Templier F, Dolveck F, Baer M, Chauvin M, Fletcher D (2003) Laboratory testing measurement of FIO2 delivered by Boussignac CPAP system with an input of 100% oxygen. Ann Fr Anesth Reanim 22:103–107PubMed Templier F, Dolveck F, Baer M, Chauvin M, Fletcher D (2003) Laboratory testing measurement of FIO2 delivered by Boussignac CPAP system with an input of 100% oxygen. Ann Fr Anesth Reanim 22:103–107PubMed
26.
Zurück zum Zitat Kallio T, Kuisma M, Alaspaa A, Rosenberg PH (2003) The use of prehospital continuous positive airway pressure treatment in presumed acute severe pulmonary edema. Prehosp Emerg Care 7:209–213PubMedCrossRef Kallio T, Kuisma M, Alaspaa A, Rosenberg PH (2003) The use of prehospital continuous positive airway pressure treatment in presumed acute severe pulmonary edema. Prehosp Emerg Care 7:209–213PubMedCrossRef
27.
Zurück zum Zitat Domenighetti G, Gayer R, Gentilini R (2002) Noninvasive pressure support ventilation in non-COPD patients with acute cardiogenic pulmonary edema and severe community-acquired pneumonia: acute effects and outcome. Intensive Care Med 28:1226–1232PubMedCrossRef Domenighetti G, Gayer R, Gentilini R (2002) Noninvasive pressure support ventilation in non-COPD patients with acute cardiogenic pulmonary edema and severe community-acquired pneumonia: acute effects and outcome. Intensive Care Med 28:1226–1232PubMedCrossRef
Metadaten
Titel
Is helmet CPAP first line pre-hospital treatment of presumed severe acute pulmonary edema?
verfasst von
Giuseppe Foti
Fabio Sangalli
Lorenzo Berra
Stefano Sironi
Marco Cazzaniga
Gian Piera Rossi
Giacomo Bellani
Antonio Pesenti
Publikationsdatum
01.04.2009
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 4/2009
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-008-1354-7

Weitere Artikel der Ausgabe 4/2009

Intensive Care Medicine 4/2009 Zur Ausgabe

Mit dem Seitenschneider gegen das Reißverschluss-Malheur

03.06.2024 Urologische Notfallmedizin Nachrichten

Wer ihn je erlebt hat, wird ihn nicht vergessen: den Schmerz, den die beim Öffnen oder Schließen des Reißverschlusses am Hosenschlitz eingeklemmte Haut am Penis oder Skrotum verursacht. Eine neue Methode für rasche Abhilfe hat ein US-Team getestet.

Schlaganfall: frühzeitige Blutdrucksenkung im Krankenwagen ohne Nutzen

31.05.2024 Apoplex Nachrichten

Der optimale Ansatz für die Blutdruckkontrolle bei Patientinnen und Patienten mit akutem Schlaganfall ist noch nicht gefunden. Ob sich eine frühzeitige Therapie der Hypertonie noch während des Transports in die Klinik lohnt, hat jetzt eine Studie aus China untersucht.

Reanimation bei Kindern – besser vor Ort oder während Transport?

29.05.2024 Reanimation im Kindesalter Nachrichten

Zwar scheint es laut einer Studie aus den USA und Kanada bei der Reanimation von Kindern außerhalb einer Klinik keinen Unterschied für das Überleben zu machen, ob die Wiederbelebungsmaßnahmen während des Transports in die Klinik stattfinden oder vor Ort ausgeführt werden. Jedoch gibt es dabei einige Einschränkungen und eine wichtige Ausnahme.

Nicht Creutzfeldt Jakob, sondern Abführtee-Vergiftung

29.05.2024 Hyponatriämie Nachrichten

Eine ältere Frau trinkt regelmäßig Sennesblättertee gegen ihre Verstopfung. Der scheint plötzlich gut zu wirken. Auf Durchfall und Erbrechen folgt allerdings eine Hyponatriämie. Nach deren Korrektur kommt es plötzlich zu progredienten Kognitions- und Verhaltensstörungen.

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.