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Clinical Autonomic Research
Erschienen in: Clinical Autonomic Research 1/2009

01.02.2009 | REVIEW ARTICLE

Sphincter EMG as a diagnostic tool in autonomic disorders

verfasst von: Ryuji Sakakibara, MD, PhD, Tomoyuki Uchiyama, Tomonori Yamanishi, Masahiko Kishi

Erschienen in: Clinical Autonomic Research | Ausgabe 1/2009

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Abstract

Multiple system atrophy (MSA) is a neurodegenerative disease presenting with a combination of parkinsonian, cerebellar, and autonomic (including cardiovascular, urinary, and anorectal) dysfunction. It is pathologically defined, but at present lacks a definitive clinical diagnostic test. The majority of patients with probable MSA have an abnormal sphincter EMG. Patients with idiopathic Parkinson’s disease do not show marked sphincter EMG abnormalities. Therefore, these abnormalities can be used to distinguish MSA from idiopathic Parkinson’s disease in the first 5 years after disease onset. In contrast, similar sphincter EMG abnormalities are found in some, though not many, patients with dementia with Lewy bodies, pure autonomic failure, progressive supranuclear palsy, and spinocerebellar ataxia type 3. Thus, the limitations of the sphincter EMG test should also be kept in mind. Sphincter EMG and relevant sacral autonomic tests are diagnostic tools for autonomic disorders, reflecting the common and significant involvement of the sacral cord in MSA.
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Metadaten
Titel
Sphincter EMG as a diagnostic tool in autonomic disorders
verfasst von
Ryuji Sakakibara, MD, PhD
Tomoyuki Uchiyama
Tomonori Yamanishi
Masahiko Kishi
Publikationsdatum
01.02.2009
Erschienen in
Clinical Autonomic Research / Ausgabe 1/2009
Print ISSN: 0959-9851
Elektronische ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-008-0489-5

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