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Journal of Neuro-Oncology

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01.02.2021 | Topic Review

Intraoperative MRI for Brain Tumors

verfasst von: Cara Marie Rogers, Pamela S. Jones, Jeffrey S. Weinberg

Erschienen in: Journal of Neuro-Oncology | Ausgabe 3/2021

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Abstract

Introduction

The use of intraoperative imaging has been a critical tool in the neurosurgeon’s armamentarium and is of particular benefit during tumor surgery. This article summarizes the history of its development, implementation, clinical experience and future directions.

Methods

We reviewed the literature focusing on the development and clinical experience with intraoperative MRI. Utilizing the authors’ personal experience as well as evidence from the literature, we present an overview of the utility of MRI during neurosurgery.

Results

In the 1990s, the first description of using a low field MRI in the operating room was published describing the additional benefit provided by improved resolution of MRI as compared to ultrasound. Since then, implementation has varied in magnetic field strength and in configuration from floor mounted to ceiling mounted units as well as those that are accessible to the operating room for use during surgery and via an outpatient entrance to use for diagnostic imaging. The experience shows utility of this technique for increasing extent of resection for low and high grade tumors as well as preventing injury to important structures while incorporating techniques such as intraoperative monitoring.

Conclusion

This article reviews the history of intraoperative MRI and presents a review of the literature revealing the successful implementation of this technology and benefits noted for the patient and the surgeon.

Black PM et al (1997) Development and implementation of intraoperative magnetic resonance imaging and its neurosurgical applications. Neurosurgery 41(4):831–842 discussion 842-5PubMedCrossRef

Mislow JM, Golby AJ, Black PM (2010) Origins of intraoperative MRI. Magn Reson Imaging Clin N Am 18(1):1–10PubMedPubMedCentralCrossRef

Schulder M, Catrambone J, Carmel PW (2005) Intraoperative magnetic resonance imaging at 0.12 T: is it enough? Neurosurg Clin N Am 16(1):143–154PubMedCrossRef

Fahlbusch R, Samii A (2016) Intraoperative MRI. Neurosurg Focus 40(3):E3PubMedCrossRef

Alexander E 3rd et al (1997) The present and future role of intraoperative MRI in neurosurgical procedures. Stereotact Funct Neurosurg 68(1–4 Pt 1):10–17PubMedCrossRef

Bisdas S et al (2015) Intraoperative MR imaging in neurosurgery. Clin Neuroradiol 25(Suppl 2):237–244PubMedCrossRef

Dietrich J et al (1999) Brain tumor resections in an open 0.5-T MRT. 2 years’ experiences from the neuroradiological viewpoint. Radiologe 39(11):988–994PubMedCrossRef

Hlavac M, Wirtz CR, Halatsch ME (2017) Intraoperative magnetic resonance imaging. HNO 65(1):25–29PubMedCrossRef

Nimsky C, Carl B (2017) Historical, current, and future intraoperative imaging modalities. Neurosurg Clin N Am 28(4):453–464PubMedCrossRef

10.

Hushek SG et al (2008) MR systems for MRI-guided interventions. J Magn Reson Imaging 27(2):253–266PubMedCrossRef

11.

Gerlach R et al (2008) Feasibility of Polestar N20, an ultra-low-field intraoperative magnetic resonance imaging system in resection control of pituitary macroadenomas: lessons learned from the first 40 cases. Neurosurgery 63(2):272–284 discussion 284-5PubMedCrossRef

12.

Kubben PL et al (2014) Intraoperative magnetic resonance imaging versus standard neuronavigation for the neurosurgical treatment of glioblastoma: a randomized controlled trial. Surg Neurol Int 5:70PubMedPubMedCentralCrossRef

13.

Mutchnick I, Moriarty TM (2014) Intraoperative MRI in pediatric neurosurgery-an update. Transl Pediatr 3(3):236–246PubMedPubMedCentral

14.

Fahlbusch R (2011) Development of intraoperative MRI: a personal journey. Acta Neurochir Suppl 109:9–16PubMedCrossRef

15.

Chicoine MR et al (2011) Implementation and preliminary clinical experience with the use of ceiling mounted mobile high field intraoperative magnetic resonance imaging between two operating rooms. Acta Neurochir Suppl 109:97–102PubMedCrossRef

16.

Choudhri AF et al (2015) Intraoperative MRI in pediatric brain tumors. Pediatr Radiol 45(Suppl 3):S397–S405PubMedCrossRef

17.

Bohinski RJ et al (2001) Glioma resection in a shared-resource magnetic resonance operating room after optimal image-guided frameless stereotactic resection. Neurosurgery 48(4):731–742 discussion 742-4PubMedCrossRef

18.

Jolesz FA (2011) Intraoperative imaging in neurosurgery: where will the future take us? Acta Neurochir Suppl 109:21–25PubMedPubMedCentralCrossRef

19.

Lippmann H, Kruggel F (2005) Quasi-real-time neurosurgery support by MRI processing via grid computing. Neurosurg Clin N Am 16(1):65–75PubMedCrossRef

20.

Elias WJ, Fu KM, Frysinger RC (2007) Cortical and subcortical brain shift during stereotactic procedures. J Neurosurg 107(5):983–988PubMedCrossRef

21.

Nimsky C et al (2000) Quantification of, visualization of, and compensation for brain shift using intraoperative magnetic resonance imaging. Neurosurgery 47(5):1070–1079 discussion 1079-80PubMedCrossRef

22.

Nabavi A et al (2001) Serial intraoperative magnetic resonance imaging of brain shift. Neurosurgery 48(4):787–797 discussion 797-8PubMed

23.

Shahar T et al (2014) Preoperative imaging to predict intraoperative changes in tumor-to-corticospinal tract distance: an analysis of 45 cases using high-field intraoperative magnetic resonance imaging. Neurosurgery 75(1):23–30PubMedCrossRef

24.

Gering DT et al (2001) An integrated visualization system for surgical planning and guidance using image fusion and an open MR. J Magn Reson Imaging 13(6):967–975PubMedCrossRef

25.

Nauta HJ (1994) Error assessment during “image guided” and “imaging interactive” stereotactic surgery. Comput Med Imaging Graph 18(4):279–287PubMedCrossRef

26.

Dho YS et al (2019) Positional effect of preoperative neuronavigational magnetic resonance image on accuracy of posterior fossa lesion localization. J Neurosurg:1–10

27.

Lacroix M et al (2001) A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. J Neurosurg 95(2):190–198PubMedCrossRef

28.

Sanai N et al (2011) An extent of resection threshold for newly diagnosed glioblastomas. J Neurosurg 115(1):3–8PubMedCrossRef

29.

Oppenlander ME et al (2014) An extent of resection threshold for recurrent glioblastoma and its risk for neurological morbidity. J Neurosurg 120(4):846–853CrossRefPubMed

30.

Scherer M et al (2019) Surgery for diffuse WHO grade II Gliomas: volumetric analysis of a Multicenter retrospective cohort from the German study Group for Intraoperative Magnetic Resonance Imaging. Neurosurgery

31.

Roelz R et al (2016) Residual tumor volume as best outcome predictor in low grade Glioma - a nine-years near-randomized survey of surgery vs. Biopsy Sci Rep 6:32286PubMedCrossRef

32.

Krivosheya D, Prabhu SS (2017) Combining functional studies with intraoperative MRI in Glioma surgery. Neurosurg Clin N Am 28(4):487–497PubMedCrossRef

33.

Rao G (2017) Intraoperative MRI and maximizing extent of resection. Neurosurg Clin N Am 28(4):477–485PubMedCrossRef

34.

Aghi MK et al (2015) The role of surgery in the management of patients with diffuse low grade glioma: a systematic review and evidence-based clinical practice guideline. J Neuro-Oncol 125(3):503–530CrossRef

35.

Hervey-Jumper SL, Berger MS (2016) Maximizing safe resection of low- and high-grade glioma. J Neuro-Oncol 130(2):269–282CrossRef

36.

Hatiboglu MA et al (2009) Impact of intraoperative high-field magnetic resonance imaging guidance on glioma surgery: a prospective volumetric analysis. Neurosurgery 64(6):1073–1081 discussion 1081PubMedCrossRef

37.

Coburger J et al (2015) Linear array ultrasound in low-grade glioma surgery: histology-based assessment of accuracy in comparison to conventional intraoperative ultrasound and intraoperative MRI. Acta Neurochir 157(2):195–206PubMedCrossRef

38.

Giordano M et al (2017) Intraoperative magnetic resonance imaging in pediatric neurosurgery: safety and utility. J Neurosurg Pediatr 19(1):77–84PubMedCrossRef

39.

Napolitano M et al (2014) Glioblastoma surgery with and without intraoperative MRI at 3.0T. Neurochirurgie 60(4):143–150PubMedCrossRef

40.

Knauth M et al (1999) Intraoperative MR imaging increases the extent of tumor resection in patients with high-grade gliomas. AJNR Am J Neuroradiol 20(9):1642–1646PubMedPubMedCentral

41.

Senft C et al (2011) Intraoperative MRI guidance and extent of resection in glioma surgery: a randomised, controlled trial. Lancet Oncol 12(11):997–1003PubMedCrossRef

42.

Senft C et al (2010) Low field intraoperative MRI-guided surgery of gliomas: a single center experience. Clin Neurol Neurosurg 112(3):237–243PubMedCrossRef

43.

Zhang Z et al (2019) High-field intraoperative magnetic resonance imaging increases extent of resection and progression-free survival for nonfunctioning pituitary adenomas. World Neurosurg 127:e925–e931PubMedCrossRef

44.

Golub D et al (2020) Intraoperative MRI versus 5-ALA in high-grade glioma resection: a network meta-analysis. J Neurosurg:1–15

45.

Masuda Y et al (2018) Evaluation of the extent of resection and detection of ischemic lesions with intraoperative MRI in glioma surgery: is intraoperative MRI superior to early postoperative MRI? J Neurosurg:1–8

46.

Sakurada K et al (2010) Detection of acute subdural hemorrhage using intraoperative MR imaging during glioma surgery: a case report. No Shinkei Geka 38(12):1115–1120PubMed

47.

Cui Z et al (2019) Early detection of cerebral ischemic events on intraoperative magnetic resonance imaging during surgical procedures for deep brain stimulation. Acta Neurochir 161(8):1545–1558PubMedCrossRef

48.

Keles GE (2004) Intracranial neuronavigation with intraoperative magnetic resonance imaging. Curr Opin Neurol 17(4):497–500PubMedCrossRef

49.

Lewin JS, Metzger A, Selman WR (2000) Intraoperative magnetic resonance image guidance in neurosurgery. J Magn Reson Imaging 12(4):512–524PubMedCrossRef

50.

Yahanda AT et al (2020) A multi-institutional analysis of factors influencing surgical outcomes for patients with newly diagnosed grade I Gliomas. World Neurosurg 135:e754–e764PubMedCrossRef

51.

Li YM et al (2016) The influence of maximum safe resection of glioblastoma on survival in 1229 patients: can we do better than gross-total resection? J Neurosurg 124(4):977–988PubMedCrossRef

52.

Coburger J et al (2016) Low-grade Glioma surgery in intraoperative magnetic resonance imaging: results of a Multicenter retrospective assessment of the German study Group for Intraoperative Magnetic Resonance Imaging. Neurosurgery 78(6):775–786PubMedCrossRef

53.

Rahman M et al (2017) The effects of new or worsened postoperative neurological deficits on survival of patients with glioblastoma. J Neurosurg 127(1):123–131PubMedCrossRef

54.

McGirt MJ et al (2009) Association of surgically acquired motor and language deficits on overall survival after resection of glioblastoma multiforme. Neurosurgery 65(3):463–469 discussion 469-70PubMedCrossRef

55.

Hall WA et al (2003) Costs and benefits of intraoperative MR-guided brain tumor resection. Acta Neurochir Suppl 85:137–142PubMedCrossRef

56.

Pichierri A, Bradley M, Iyer V (2019) Intraoperative magnetic resonance imaging-guided Glioma resections in awake or asleep settings and feasibility in the context of a public health system. World Neurosurg X 3:100022PubMedPubMedCentralCrossRef

57.

Pollack IF, Agnihotri S, Broniscer A (2019) Childhood brain tumors: current management, biological insights, and future directions. J Neurosurg Pediatr 23(3):261–273PubMedPubMedCentralCrossRef

58.

Day EL, Scott RM (2019) The utility of intraoperative MRI during pediatric brain tumor surgery: a single-surgeon case series. J Neurosurg Pediatr:1–7

59.

Karsy M et al (2019) Evaluation of pediatric glioma outcomes using intraoperative MRI: a multicenter cohort study. J Neuro-Oncol 143(2):271–280CrossRef

60.

Giordano M et al (2016) Neurosurgical tools to extend tumor resection in pediatric hemispheric low-grade gliomas: iMRI. Childs Nerv Syst 32(10):1915–1922PubMedCrossRef

61.

Shah MN et al (2012) Intraoperative magnetic resonance imaging to reduce the rate of early reoperation for lesion resection in pediatric neurosurgery. J Neurosurg Pediatr 9(3):259–264PubMedCrossRef

62.

Lara-Almunia M, Hernandez-Vicente J (2019) Frame-based stereotactic biopsy: description and Association of Anatomical, radiologic, and surgical variables with diagnostic yield in a series of 407 cases. J Neurol Surg A Cent Eur Neurosurg 80(3):149–161PubMedCrossRef

63.

Chen CC et al (2009) Stereotactic brain biopsy: single center retrospective analysis of complications. Clin Neurol Neurosurg 111(10):835–839PubMedCrossRef

64.

Silva EU et al (2009) Stereotactic biopsy for intracranial lesions: clinical-pathological compatibility in 60 patients. Arq Neuropsiquiatr 67(4):1062–1065PubMedCrossRef

65.

Ersahin M et al (2011) The safety and diagnostic value of frame-based and CT-guided stereotactic brain biopsy technique. Turk Neurosurg 21(4):582–590PubMed

66.

Bernays RL et al (2002) Histological yield, complications, and technological considerations in 114 consecutive frameless stereotactic biopsy procedures aided by open intraoperative magnetic resonance imaging. J Neurosurg 97(2):354–362PubMedCrossRef

67.

Kucharczyk J et al (2001) Cost-efficacy of MR-guided neurointerventions. Neuroimaging Clin N Am 11(4):767–772 xiiPubMed

68.

Chakraborty S et al (2017) Intraoperative MRI for resection of intracranial meningiomas. J Exp Ther Oncol 12(2):157–162PubMed

69.

Zaidi HA et al (2016) The utility of high-resolution intraoperative MRI in endoscopic transsphenoidal surgery for pituitary macroadenomas: early experience in the advanced multimodality image guided operating suite. Neurosurg Focus 40(3):E18PubMedPubMedCentralCrossRef

70.

Coburger J et al (2014) Determining the utility of intraoperative magnetic resonance imaging for transsphenoidal surgery: a retrospective study. J Neurosurg 120(2):346–356PubMedCrossRef

71.

Hlavac M et al (2019) Intraoperative MRI in transsphenoidal resection of invasive pituitary macroadenomas. Neurosurg Rev 42(3):737–743PubMedCrossRef

72.

Sylvester PT et al (2015) Combined high-field intraoperative magnetic resonance imaging and endoscopy increase extent of resection and progression-free survival for pituitary adenomas. Pituitary 18(1):72–85PubMedPubMedCentralCrossRef

73.

Thomas JG et al (2016) Laser interstitial thermal therapy for newly diagnosed and recurrent glioblastoma. Neurosurg Focus 41(4):E12PubMedCrossRef

74.

Swartz LK et al (2019) Outcomes in patients treated with laser interstitial thermal therapy for primary brain Cancer and brain metastases. Oncologist

75.

Ali FS et al (2019) Cerebral radiation necrosis: incidence, pathogenesis, diagnostic challenges, and future opportunities. Curr Oncol Rep 21(8):66PubMedCrossRef

76.

Mohyeldin A, Elder JB (2017) Stereotactic biopsy platforms with intraoperative imaging guidance. Neurosurg Clin N Am 28(4):465–475PubMedCrossRef

77.

Bartek J Jr et al (2019) Biopsy and ablation of H3K27 Glioma using skull-mounted Smartframe device: technical case report. World Neurosurg 127:436–441PubMedCrossRef

78.

Pruitt R et al (2017) Complication avoidance in laser interstitial thermal therapy: lessons learned. J Neurosurg 126(4):1238–1245PubMedCrossRef

79.

Salem U et al (2019) Neurosurgical applications of MRI guided laser interstitial thermal therapy (LITT). Cancer Imaging 19(1):65PubMedPubMedCentralCrossRef

80.

Hatiboglu MA et al (2010) Utilization of intraoperative motor mapping in glioma surgery with high-field intraoperative magnetic resonance imaging. Stereotact Funct Neurosurg 88(6):345–352PubMedCrossRef

81.

Maldaun MV et al (2014) Awake craniotomy for gliomas in a high-field intraoperative magnetic resonance imaging suite: analysis of 42 cases. J Neurosurg 121(4):810–817PubMedCrossRef

82.

Leuthardt EC et al (2011) Use of movable high-field-strength intraoperative magnetic resonance imaging with awake craniotomies for resection of gliomas: preliminary experience. Neurosurgery 69(1):194–205 discussion 205-6PubMedCrossRef

83.

Coburger J et al (2015) Surgery for Glioblastoma: impact of the combined use of 5-Aminolevulinic acid and intraoperative MRI on extent of resection and survival. PLoS One 10(6):e0131872PubMedPubMedCentralCrossRef

84.

Coburger J, Wirtz CR (2019) Fluorescence guided surgery by 5-ALA and intraoperative MRI in high grade glioma: a systematic review. J Neuro-Oncol 141(3):533–546CrossRef

85.

Barone DG, Lawrie TA, Hart MG (2014) Image guided surgery for the resection of brain tumours. Cochrane Database Syst Rev 1:CD009685

86.

Berkow LC (2016) Anesthetic management and human factors in the intraoperative MRI environment. Curr Opin Anaesthesiol 29(5):563–567PubMedCrossRef

87.

Lu CY et al (2018) Clinical application of 3.0 T intraoperative magnetic resonance combined with multimodal neuronavigation in resection of cerebral eloquent area glioma. Medicine (Baltimore) 97(34):e11702CrossRef

88.

89.

Makary M et al (2011) Clinical and economic outcomes of low-field intraoperative MRI-guided tumor resection neurosurgery. J Magn Reson Imaging 34(5):1022–1030PubMedCrossRef

90.

Kubben PL et al (2012) Correlation between contrast enhancement on intraoperative magnetic resonance imaging and histopathology in glioblastoma. Surg Neurol Int 3:158PubMedPubMedCentralCrossRef

91.

Cherkashin MA et al (2016) Surgical safety cheklist at the management of the hybrid operating room. Angiol Sosud Khir 22(2):54–59PubMed

92.

Iturri-Clavero F et al (2016) “Low-field” intraoperative MRI: a new scenario, a new adaptation. Clin Radiol 71(11):1193–1198PubMedCrossRef

93.

Henrichs B, Walsh RP (2014) Intraoperative MRI for neurosurgical and general surgical interventions. Curr Opin Anaesthesiol 27(4):448–452PubMedCrossRef

94.

Board, A. WSJ: Intraoperative imaging gaining traction. February 19, 2015 18, 2020]; Available from: https://www.advisory.com/daily-briefing/2015/02/19/intraoperative%20imaging

95.

RL, B (2010) Intraoperative Imaging: Current Trends, Technology, and Future Directions, in Transsphenoidal Surgery, G.L. ER Laws, (Ed). p. 56–69

96.

Database, A.A.S. (2016) Percentage of Hospitals with Access to Intraoperative Magnetic Resonance Imaging. 2016 September 18. 2020]; Available from: https://www.neimanhpi.org/data_series/percentage-of-hospitals-with-access-to-intraoperative-magnetic-resonance-imaging/#/map/2016

97.

PubMed. 2020 9/22/2020]; Available from: https://pubmed.ncbi.nlm.nih.gov/?term=intraoperative+mri+and+brain+tumors

98.

Jenkinson MD et al (2018) Intraoperative imaging technology to maximise extent of resection for glioma. Cochrane Database Syst Rev 1:CD012788PubMed

Titel: Intraoperative MRI for Brain Tumors
verfasst von: Cara Marie Rogers
Pamela S. Jones
Jeffrey S. Weinberg
Publikationsdatum: 01.02.2021
Verlag: Springer US
Erschienen in: Journal of Neuro-Oncology / Ausgabe 3/2021
Print ISSN: 0167-594X
Elektronische ISSN: 1573-7373
DOI: https://doi.org/10.1007/s11060-020-03667-6

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