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Current Cardiology Reports
Erschienen in: Current Cardiology Reports 4/2018

01.04.2018 | Ischemic Heart Disease (D Mukherjee, Section Editor)

Effect of Alcohol Consumption on Cardiovascular Health

verfasst von: Sunny Goel, Abhishek Sharma, Aakash Garg

Erschienen in: Current Cardiology Reports | Ausgabe 4/2018

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Abstract

Purpose of Review

This review aims to discuss the effect of alcohol consumption on various cardiovascular (CV) diseases and CV mortality.

Recent Findings

Alcohol intake has consistently shown a J- or U-shaped relationship with several cardiovascular diseases. Light to moderate alcohol intake has been associated with lower risk of coronary artery disease, heart failure (HF), as well as CV mortality. On the other hand, heavy consumption has been associated with deleterious CV outcomes including increased mortality. However, the evidence is based from observational and population-based studies where risk of confounding cannot be excluded even after meticulous methodological approaches. This is compounded by conflicting data such as higher risk of certain CV diseases like HF in former drinkers compared to abstainers. Further, Mendelian randomization studies using genetic polymorphisms in enzymes have recently questioned the beneficial association of low-moderate drinking with CV system.

Summary

There has been substantial and consistent evidence that light to moderate alcohol consumption have beneficial effect on overall cardiovascular profile and mortality. However, there are considerable limitations in the reported literature to determine a strong causality of a protective effect of moderate alcohol consumption by itself. Further robust studies or possibly a well-structured randomized controlled could bring an end to this debate.
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Metadaten
Titel
Effect of Alcohol Consumption on Cardiovascular Health
verfasst von
Sunny Goel
Abhishek Sharma
Aakash Garg
Publikationsdatum
01.04.2018
Verlag
Springer US
Erschienen in
Current Cardiology Reports / Ausgabe 4/2018
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-018-0962-2

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