Skip to main content
Erschienen in: Drug Safety 2/2013

01.02.2013 | Short Communication

A Comparison of the Reliability of Smartphone Apps for Opioid Conversion

verfasst von: Faye Haffey, Richard R. W. Brady, Simon Maxwell

Erschienen in: Drug Safety | Ausgabe 2/2013

Einloggen, um Zugang zu erhalten

Abstract

Background

Many medical professionals use smartphone applications (apps) on a daily basis to support clinical decision making. Opioid switching (conversion of one opioid to another at equianalgesic dose) is common in clinical practice and often challenging for doctors. Apps providing an opioid conversion tool can therefore be a useful resource. Despite rapid growth in the use of medical apps, the lack of robust regulation and peer review to ensure the accuracy and reliability of app content is currently an area of concern.

Method

We searched major online app stores for apps providing an opioid dose conversion tool. We assessed output variability between apps in the dose calculation of seven opioid switches, as well as assessing the level of professional medical involvement in the authorship, creation and design of the apps.

Results

Of 23 different apps identified, more than half (n = 12; 52 %) had no stated medical professional involvement and only 11 (48 %) apps provided direct references to primary sources for their opioid conversion ratios. Conversion of 1 mg of oral morphine to oral codeine demonstrated the largest conversion output range (median 6.67 mg, range 3.333–12 mg). Conversion of 1 mg of oral morphine to methadone ranged from 0.05–0.67 mg, with only 44 % of methadone-converting apps (n = 4) commenting that the conversion ratio changes with magnitude of methadone dose. Overall, 35 % of apps (n = 8) did not warn the user about the standard practice of dose reduction when opioid switching. There was a statistically significant difference in the mean conversion output for hydromorphone (oral) between apps with and without medical professional involvement (0.2256 vs 0.2536; p = 0.0377).

Conclusions

There are significant concerns with regard to the reliability of information provided by apps offering opioid dose conversion, with lack of information regarding evidence-based content and peer review in many cases. It is crucial that better regulation of medical apps is instigated in order to ensure that patient safety is maintained.
Literatur
1.
Zurück zum Zitat World Health Organisation. Cancer pain relief and palliative care. Geneva: World Health Organisation; 1996. World Health Organisation. Cancer pain relief and palliative care. Geneva: World Health Organisation; 1996.
2.
Zurück zum Zitat Knotkova H, Fine PG, Portenoy R. Opioid rotation: the science and the limitations of the equianalgesic dose table. J Pain Symptom Manage. 2009;38(3):426–39.PubMedCrossRef Knotkova H, Fine PG, Portenoy R. Opioid rotation: the science and the limitations of the equianalgesic dose table. J Pain Symptom Manage. 2009;38(3):426–39.PubMedCrossRef
4.
Zurück zum Zitat Quigley C. Opioid switching to improve pain relief and drug tolerability. Cochrane Database Syst Rev 2004;(3):CD004847. Quigley C. Opioid switching to improve pain relief and drug tolerability. Cochrane Database Syst Rev 2004;(3):CD004847.
5.
Zurück zum Zitat Shaheen PE, Walsh D, Lasheen W, et al. Opioid equianalgesic tables: are they all equally dangerous? J Pain Symptom Manage. 2009;38(3):409–17.PubMedCrossRef Shaheen PE, Walsh D, Lasheen W, et al. Opioid equianalgesic tables: are they all equally dangerous? J Pain Symptom Manage. 2009;38(3):409–17.PubMedCrossRef
6.
Zurück zum Zitat Pereira J, Lawlor P, Vigano A, et al. Equianalgesic dose ratios for opioids: a critical review and proposals for long-term dosing. J Pain Symptom Manage. 2001;22(2):672–87.PubMedCrossRef Pereira J, Lawlor P, Vigano A, et al. Equianalgesic dose ratios for opioids: a critical review and proposals for long-term dosing. J Pain Symptom Manage. 2001;22(2):672–87.PubMedCrossRef
7.
Zurück zum Zitat Visvanathan A, Hamilton A, Brady RRW. Smartphone apps in microbiology: is better regulation required? Clin Microbiol Infect. 2012;18(7):e218–20.PubMedCrossRef Visvanathan A, Hamilton A, Brady RRW. Smartphone apps in microbiology: is better regulation required? Clin Microbiol Infect. 2012;18(7):e218–20.PubMedCrossRef
8.
Zurück zum Zitat Franko OI, Tirrell TF. Smartphone app use among medical providers in ACGME training programs. J Med Syst. Epub 2011 Nov 4. Franko OI, Tirrell TF. Smartphone app use among medical providers in ACGME training programs. J Med Syst. Epub 2011 Nov 4.
9.
Zurück zum Zitat Heaton A, Webb DJ, Maxwell SRJ. Undergraduate preparation for prescribing: the views of 2314 UK medical students and recent graduates. Br J Clin Pharmacol. 2008;66(1):128–34.PubMedCrossRef Heaton A, Webb DJ, Maxwell SRJ. Undergraduate preparation for prescribing: the views of 2314 UK medical students and recent graduates. Br J Clin Pharmacol. 2008;66(1):128–34.PubMedCrossRef
10.
Zurück zum Zitat Dornan T, Ashcroft D, Heathfield H, et al. An in depth investigation into causes of prescribing errors by foundation trainees in relation to their medical education—EQUIP study. London: General Medical Council; 2009. Dornan T, Ashcroft D, Heathfield H, et al. An in depth investigation into causes of prescribing errors by foundation trainees in relation to their medical education—EQUIP study. London: General Medical Council; 2009.
11.
Zurück zum Zitat Rothwell C, Burford B, Morrison J, et al. Junior doctors prescribing: enhancing their learning in practice. Br J Clin Pharmacol. 2012;73(2):194–202.PubMedCrossRef Rothwell C, Burford B, Morrison J, et al. Junior doctors prescribing: enhancing their learning in practice. Br J Clin Pharmacol. 2012;73(2):194–202.PubMedCrossRef
14.
Zurück zum Zitat Shaheen PE, Legrand SB, Walsh D, et al. Errors in opioid prescribing: a prospective survey in cancer pain. J Pain Symptom Manage. 2010;39(4):702–11.PubMedCrossRef Shaheen PE, Legrand SB, Walsh D, et al. Errors in opioid prescribing: a prospective survey in cancer pain. J Pain Symptom Manage. 2010;39(4):702–11.PubMedCrossRef
15.
Zurück zum Zitat Rich BA, Webster LR. A review of forensic implications of opioid prescribing with examples from malpractice cases involving opioid-related overdose. Pain Med. 2011;12(Suppl. 2):59–65.CrossRef Rich BA, Webster LR. A review of forensic implications of opioid prescribing with examples from malpractice cases involving opioid-related overdose. Pain Med. 2011;12(Suppl. 2):59–65.CrossRef
16.
Zurück zum Zitat National Institute for Health and Clinical Excellence. Opioids in palliative care: safe and effective prescribing of strong opioids for pain in palliative care of adults (CG140). London: National Institute for Health and Clinical Excellence; 2012. National Institute for Health and Clinical Excellence. Opioids in palliative care: safe and effective prescribing of strong opioids for pain in palliative care of adults (CG140). London: National Institute for Health and Clinical Excellence; 2012.
17.
Zurück zum Zitat Plagge H, Ruppen W, Ott N, et al. Dose calculation in opioid rotation: electronic calculator vs manual calculation. Int J Clin Pharm. 2011;33:25–32.PubMedCrossRef Plagge H, Ruppen W, Ott N, et al. Dose calculation in opioid rotation: electronic calculator vs manual calculation. Int J Clin Pharm. 2011;33:25–32.PubMedCrossRef
18.
Zurück zum Zitat Kho A, Henderson E, Dressler DD, et al. Use of handheld computers in medical education. J Gen Intern Med. 2006;21:531–7.PubMedCrossRef Kho A, Henderson E, Dressler DD, et al. Use of handheld computers in medical education. J Gen Intern Med. 2006;21:531–7.PubMedCrossRef
19.
Zurück zum Zitat Maxwell S, Mucklow J. e-Learning initiatives to support prescribing. Br J Clin Pharmacol. Epub 2012 Apr 18. Maxwell S, Mucklow J. e-Learning initiatives to support prescribing. Br J Clin Pharmacol. Epub 2012 Apr 18.
20.
Zurück zum Zitat Davies BS, Rafique J, Vincent TR, et al. Mobile Medical Education (MoMEd). How mobile information resources contribute to learning for undergraduate clinical students: a mixed methods study. BMC Med Educ. 2012;12(12):1.PubMedCrossRef Davies BS, Rafique J, Vincent TR, et al. Mobile Medical Education (MoMEd). How mobile information resources contribute to learning for undergraduate clinical students: a mixed methods study. BMC Med Educ. 2012;12(12):1.PubMedCrossRef
21.
Zurück zum Zitat Flannigan C, McAloon J. Students prescribing emergency drug infusions utilising smartphones outperformed consultants using the BNFCs. Resuscitation. 2011;82(11):1424–7.PubMedCrossRef Flannigan C, McAloon J. Students prescribing emergency drug infusions utilising smartphones outperformed consultants using the BNFCs. Resuscitation. 2011;82(11):1424–7.PubMedCrossRef
22.
Zurück zum Zitat McQueen DS, Begg MJ, Maxwell SR. eDrugCalc: an online self-assessment package to enhance medical students’ drug dose calculation skills. Br J Clin Pharmacol. 2010;70(4):492–9.PubMedCrossRef McQueen DS, Begg MJ, Maxwell SR. eDrugCalc: an online self-assessment package to enhance medical students’ drug dose calculation skills. Br J Clin Pharmacol. 2010;70(4):492–9.PubMedCrossRef
23.
Zurück zum Zitat Hamilton AD, Brady RR. Medical professional involvement in smartphone apps in dermatology. Br J Dermatol. Epub 2012 Jan 27. Hamilton AD, Brady RR. Medical professional involvement in smartphone apps in dermatology. Br J Dermatol. Epub 2012 Jan 27.
24.
Zurück zum Zitat O’Neill S, Brady RRW. Colorectal apps; opportunities and risks. Colorectal Dis. 2012;14(9):1043–170.CrossRef O’Neill S, Brady RRW. Colorectal apps; opportunities and risks. Colorectal Dis. 2012;14(9):1043–170.CrossRef
25.
Zurück zum Zitat Rosser BA, Eccleston C. Smartphone applications for pain management. J Telemed Telecare. 2011;17(6):308–12.PubMedCrossRef Rosser BA, Eccleston C. Smartphone applications for pain management. J Telemed Telecare. 2011;17(6):308–12.PubMedCrossRef
Metadaten
Titel
A Comparison of the Reliability of Smartphone Apps for Opioid Conversion
verfasst von
Faye Haffey
Richard R. W. Brady
Simon Maxwell
Publikationsdatum
01.02.2013
Verlag
Springer International Publishing AG
Erschienen in
Drug Safety / Ausgabe 2/2013
Print ISSN: 0114-5916
Elektronische ISSN: 1179-1942
DOI
https://doi.org/10.1007/s40264-013-0015-0

Weitere Artikel der Ausgabe 2/2013

Drug Safety 2/2013 Zur Ausgabe