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Urinary and Sexual Function After Total Mesorectal Excision

  • Conference paper
Rectal Cancer Treatment

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 165))

Abstract

The autonomous pelvic nerves are in close contact to the visceral pelvic fascia that surrounds the mesorectum. The concept of total mesorectal excsion (TME) in rectal cancer treatment has led to a substantial improvement of autonomous pelvic nerve preservation. Consecutively, this highly precise and sharp dissection technique under direct vision reduces the problem of accidental bladder denervation from 50–60% with conventional rectal cancer surgery to less than 20% with TME and the problem of postoperative impotence from 70–100% to less than 30%. The learning curve in this technically demanding procedure plays a major role with regard to a satisfying nerve preservation. The laparoscopic approach for TME allows to obtain similarly favorable results with regard to postoperative urogenital function, at least for tumors situated in the middle and upper third of the rectum, compared with open surgery. The present paper describes and depictures in detail the anatomy and the pathophysiology of autonomic pelvic nerves, the surgical technique for nerve preservation and gives a short overview of the results in the literature including own data.

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References

  1. Baader B, Herrmann M (2003) Topography of the pelvic autonomic nervous system and its potential impact on surgical intervention in the pelvis. Clin Anat 16:119–130

    Article  PubMed  Google Scholar 

  2. Büchler MW, Heald RJ, Maurer CA, Ulrich B (eds) (1998) Rektumkarzinom: das Konzept der ttotalen mesorektalen Exzision, S. Karger, Basel

    Google Scholar 

  3. Cunsolo A, Bragaglia RB, Manara G, Poggioli G, Gozzetti G (1990) Urogenital dysfunction after abdominoperineal resection for carcinomaof the rectum. Dis Colon Rectum 33:918–922

    Article  PubMed  Google Scholar 

  4. Enker WE (1992) Potency, cure, and local control in the operative treatment of rectal cancer. Arch Surg 127:1396–1401; discussion 1402

    PubMed  Google Scholar 

  5. Hanna NN, Guillem J, Dosoretz A, Steckelman E, Minsky BD, Cohen AM (2002) Intraoperative parasympathetic nerve stimulation with tumescence monitoring during total mesorectal excision for rectal cancer. J Am Coll Surg 195:506–512

    Article  PubMed  Google Scholar 

  6. Havenga K, DeRuiter MC, Enker WE, Welvaart K (1996) Anatomical basis of autonomic nerve-preserving total mesorectal excision for rectal cancer. Br J Surg 83:384–388

    PubMed  Google Scholar 

  7. Havenga K, Enker WE, McDermott K, Cohen AM, Minsky BD, Guillem J (1996) Male and female sexual and urinary function after total mesorectal excision with autonomic nerve preservation for carcinoma of the rectum. J Am Coll Surg 182:495–502

    PubMed  Google Scholar 

  8. Heald RJ (1995) Totalmesorectal excision is optimal surgery for rectal cancer: a Scandinavian consensus. Br J Surg 82:1297–1299

    PubMed  Google Scholar 

  9. Heald RJ, Husband EM, Ryall RD (1982) The mesorectum in rectal cancer surgery-the clue to pelvic recurrence? Br J Surg 69:613–616

    PubMed  Google Scholar 

  10. Hojo K, Vernava AM 3rd, Sugihara K, Katumata K (1991) Preservation of urine voiding and sexual function after rectal cancer surgery. Dis Colon Rectum 34:532–539

    Article  PubMed  Google Scholar 

  11. Hollabaugh RS, Steiner MS, Dmochowski RR (2001) Neuroanatomy of the female continence complex: clinical implications. Urology 57:382–388

    Article  PubMed  Google Scholar 

  12. Junginger T, Kneist W, Heintz A (2003) Influence of identification and preservation of pelvic autonomic nerves in rectal cancer surgery on bladder dysfunction after total mesorectal excision. Dis Colon Rectum 46:621–628

    Article  PubMed  Google Scholar 

  13. Kim NK, Aahn TW, Park JK, Lee KY, Lee WH, Sohn SK, Min JS (2002) Assessment of sexual and voiding function after total mesorectal excision with pelvic autonomic nerve preservation in males with rectal cancer. Dis Colon Rectum 45:1178–1185

    Article  PubMed  Google Scholar 

  14. Kinn AC, Ohman U (1986) Bladder and sexual function after surgery for rectal cancer. Dis Colon Rectum 29:43–48

    PubMed  Google Scholar 

  15. Koukouras D, Spiliotis J, Scopa CD, Dragotis K, Kalfarentzos F, Tzoracoleftherakis E, Androulakis J (1991) Radical consequence in the sexuality of male patients operated for colorectal carcinoma. Eur J Surg Oncol 17:285–288

    PubMed  Google Scholar 

  16. Lacy AM, Garcia-Valdecasas JC, Delgado S, Castells A, Taura P, Pique JM, Visa J (2002) Laparoscopy-assisted colectomy versusopencolectomy for treatmentofnon-metastatic colon cancer: a randomised trial. Lancet 359:2224–2229

    Article  PubMed  Google Scholar 

  17. Leveckis J, Boucher NR, Parys BT, Reed MW, Shorthouse AJ, Anderson JB (1995) Bladder and erectile dysfunction before and after rectal surgery for cancer. Br J Urol 76:752–756

    PubMed  Google Scholar 

  18. Lindsey I, Guy RJ, Warren BF, Mortensen NJ (2000) Anatomy of Denonvilliers' fascia and ppelvic nerves, impotence, and implications for the colorectal surgeon. Br J Surg 87:1288–1299

    Article  PubMed  Google Scholar 

  19. Maas CP, Moriya Y, Steup WH, Kiebert GM, Kranenbarg WM, van de Velde CJ (1998) Radical and nerve-preserving surgery for rectal cancer in The Netherlands: a prospective study on morbidity and functional outcome. Br J Surg 85:92–97

    Article  PubMed  Google Scholar 

  20. Maurer CA, Renzulli P, Meyer JD, Buchler MW (1999) Rectal carcinoma. Optimizing therapy by partial or total mesorectum removal. Zentralbl Chir 124:428–435

    PubMed  Google Scholar 

  21. Maurer CA, Z'Graggen K, Renzulli P, Schilling MK, Netzer P, Buchler MW (2001) Total mmesorectal excision preserves male genital function compared with conventional rectal cancer surgery. Br J Surg 88:1501–1505

    Article  PubMed  Google Scholar 

  22. McCall JL (1997) Total mesorectal excision: evaluating the evidence. Aust N Z J Surg 67:599–602

    PubMed  Google Scholar 

  23. Morino M, Parini U, Giraudo G, Salval M, Brachet Contul R, Garrone C (2003) Laparoscopic total mesorectal excision: a consecutive series of 100 patients. Ann Surg 237:335–342

    Article  PubMed  Google Scholar 

  24. Nagawa H, Muto T, Sunouchi K, Higuchi Y, Tsurita G, Watanabe T, Sawada T (2001) Randomized, controlled trial of lateral node dissection vs. nerve-preserving resection in patients with rectal cancer after preoperative radiotherapy. Dis Colon Rectum 44:1274–1280

    Google Scholar 

  25. Nesbakken A, Nygaard K, Bull-Njaa T, Carlsen E, Eri LM (2000) Bladder and sexual dysfunction after mesorectal excision for rectal cancer. Br J Surg 87:206–210

    Article  PubMed  Google Scholar 

  26. Parker SL, Tong T, Bolden S, Wingo PA (1997) Cancer statistics. CA Cancer J Clin. 47:5–27

    PubMed  Google Scholar 

  27. Pocard M, Zinzindohoue F, Haab F, Caplin S, Parc R, Tiret E (2002) A prospective study of sexual and urinary function before and after totalmesorectal excision with autonomic nerve preservation for rectal cancer. Surgery 131:368–372

    Article  PubMed  Google Scholar 

  28. Quah HM, Jayne DG, Eu KW, Seow-Choen F (2002) Bladder and sexual dysfunction following laparoscopically assisted and conventional open mesorectal resection for cancer. Br J Surg 89:1551–1556

    Article  PubMed  Google Scholar 

  29. Rullier E, Sa Cunha A, Couderc P, Rullier A, Gontier R, Saric J (2003) Laparoscopic intersphincteric resectionwith coloplasty and coloanal anastomosis formid and lowrectal cancer. Br J Surg 90:445–451

    Article  PubMed  Google Scholar 

  30. Saito N, Sarashina H, Nunomura M, Koda K, Takiguchi N, Nakajima N (1998) Clinical evaluation of nerve-sparing surgery combined with preoperative radiotherapy in advanced rectal cancer patients. Am J Surg 175:277–282

    Article  PubMed  Google Scholar 

  31. Taguchi K, Tsukamoto T, Murakami G (1999) Anatomical studies of the autonomic nervous system in the human pelvis by the whole-mount staining method: left-right communicating nerves between bilateral pelvic plexuses. J Urol 161:320–325

    Article  PubMed  Google Scholar 

  32. Winawer SJ, Fletcher RH, Miller L, Godlee F, Stolar MH, Mulrow CD, Woolf SH, Glick SN, Ganiats TG, Bond JH, Rosen L, Zapka JG, Olsen SJ, Giardiello FM, Sisk JE, Van Antwerp R, Brown-Davis C, Marciniak DA, Mayer RJ (1997) Colorectal cancer screening: clinical guidelines and rationale. Gastroenterology 112:594–642

    Article  PubMed  Google Scholar 

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Maurer, C.A. (2005). Urinary and Sexual Function After Total Mesorectal Excision. In: Büchler, M.W., Weitz, J., Ulrich, B., Heald, R.J. (eds) Rectal Cancer Treatment. Recent Results in Cancer Research, vol 165. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27449-9_21

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  • DOI: https://doi.org/10.1007/3-540-27449-9_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-23341-1

  • Online ISBN: 978-3-540-27449-0

  • eBook Packages: MedicineMedicine (R0)

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